GLYCERIN SUPPOS (INFANT)

Glycerin suppositories primarily work by drawing water into the stool through osmosis, which softens the stool and promotes bowel movements. When inserted rectally, glycerin, the active ingredient, comes into contact with the rectal mucosa. Glycerin is a hygroscopic agent, meaning it has the ability to attract and retain moisture from the surrounding environment. This action increases the water content within the stool, making it softer and easier to pass. The softened stool then stimulates the rectal walls, triggering the defecation reflex and facilitating the evacuation of the bowels. The mechanism of action is rapid and typically leads to a bowel movement within 15 to 60 minutes after insertion.

Rectal emollient.

Suppository

The following are the uses of Glycerine Suppository:

• Used for relieving occasional constipation and irregular bowel movements.
• Used for softening stool and easing the passing of stool, especially in cases of hemorrhoids or post-surgical conditions.
• Used for stimulating bowel movement in individuals with certain medical conditions or during travel.
• Used for providing a gentle and effective way to promote bowel evacuation in patients with limited mobility or after childbirth.
• Used for aiding in the management of chronic constipation when other treatments have not been successful.
• Used for preparing the bowel for medical procedures such as colonoscopy or surgery.
• Used for short-term relief of constipation-related symptoms like bloating and discomfort.
• Used for helping restore bowel function after prolonged periods of constipation.

In the case of an overdose of Glycerine Suppositories, it is important to recognize the signs and take appropriate action. Symptoms may include severe diarrhea, abdominal pain, and dehydration. If an overdose is suspected, promptly remove any remaining suppository and seek medical advice. Treatment focuses on managing symptoms, rehydration, and addressing any electrolyte imbalances that may occur due to excessive diarrhea. Timely intervention can help prevent further complications.

In the case of a missed dose of Glycerine Suppository, it is generally recommended to administer the suppository as soon as you remember. However, if it's almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. It is important not to double the dose to make up for a missed one. If you miss multiple doses, contact your healthcare provider for guidance, especially if you are experiencing persistent constipation or other related symptoms. They will advise you on the appropriate course of action to ensure the effectiveness of the treatment.

To use a Glycerine Suppository, remove the wrapper, moisten the tip with water, gently insert the tapered end into the rectum, pushing it slightly inward with your finger, and ensure it is comfortable; the suppository will dissolve and provide relief.

Here are the situations or conditions when Glycerin Suppositories should not be used:

• Not suitable for individuals with a known allergy or sensitivity to glycerin or any other ingredients in the suppository.
• Contraindicated in patients with an anal or rectal obstruction, inflammation, or recent surgery.
• Should not be used in cases of severe dehydration or electrolyte imbalance.
• Not recommended for individuals with a recent history of rectal bleeding or hemorrhoids.
• Avoid using in patients with severe abdominal pain, nausea, or vomiting.
• Contraindicated during rectal or anal conditions like fissures, fistulas, or recent rectal surgery.
• Not suitable for infants or children with a low body weight or those who are dehydrated.
• Should not be used if the suppository is damaged, melted, or discolored.

The side effects of Glycerine Suppository may include:

• Rectal irritation or burning sensation
• Diarrhea
• Rectal bleeding or pain during bowel movements
• Itching or discomfort around the anus
• Cramping or discomfort in the lower abdomen
• Skin rash or redness at the site of insertion
• Allergic reactions (such as hives, itching, or difficulty breathing)

Following are the precautions and warnings for Glycerine Suppository:

• Not recommended for individuals with a history of allergy or hypersensitivity to glycerin or any other ingredients in the suppository.
• Use with caution in elderly patients, as they may be more susceptible to rectal irritation or damage.
• Avoid using if you have rectal bleeding, inflammation, or any other rectal issues. Seek medical advice if you have these conditions.
• Do not exceed the recommended dosage, as excessive use may lead to rectal irritation or damage.
• If symptoms persist or worsen after using the suppository, discontinue use and consult a healthcare professional.
• Keep out of reach of children. Store in a cool, dry place away from direct sunlight.
• Consult a doctor or pharmacist if you are pregnant, planning to become pregnant, or breastfeeding before using this product.

Following are the drug interactions for Glycerine Suppository:

• No significant drug interactions have been reported with glycerine suppositories, as they are not significantly absorbed into the systemic circulation.
• However, it is still advisable to consult a healthcare professional if you are using any other medications concurrently.
• Glycerine suppositories can interact with other rectal medications, such as corticosteroids or local anesthetics, potentially affecting their absorption and efficacy.
• The use of other laxatives or stool softeners in conjunction with glycerine suppositories may increase the risk of dehydration and electrolyte imbalances.
• Antidiarrheal medications, when used simultaneously with glycerine suppositories, may reduce the effectiveness of both treatments.
• There is a potential interaction with oral medications, as glycerine suppositories may stimulate bowel movements and affect the absorption of orally administered drugs.
• Caution should be exercised when using glycerine suppositories in patients with conditions affecting the rectum or colon, as it may interact with medications used to treat these conditions.
• Always inform your doctor or pharmacist about all the medications and supplements you are taking to ensure safe and effective use.

Following are the food interactions for Glycerine Suppositories:

• As Glycerine Suppositories are rectal suppositories, there is minimal direct interaction with food.
• Generally, it is safe to consume food and beverages as usual while using these suppositories.
• Avoid consuming excessive amounts of alcohol as it may cause dehydration, potentially reducing the effectiveness of the suppositories.
• There is no need to adjust your diet or avoid specific foods when using Glycerine Suppositories.
• They are designed to act locally in the rectum and do not require systemic absorption, so food intake is not a significant factor.
• Ensure adequate hydration by drinking enough water, as this can aid in constipation relief and support the action of the suppositories.
• If you have any specific dietary concerns or conditions, consult your healthcare provider for personalized advice.
• No known food restrictions are associated with Glycerine Suppositories, allowing for flexibility in meal planning during use.

Glycerine Suppository should be stored in a cool and dry place, preferably at room temperature, ensuring it is not exposed to direct sunlight or moisture. It is crucial to keep the suppositories in their original packaging, tightly sealed, to maintain their integrity and prevent contamination. Avoid storing them in hot or humid environments like bathrooms or kitchens, as temperature fluctuations can impact their effectiveness. Always check the expiration date before use and never use expired suppositories. When disposing of unused or expired glycerine suppositories, do not flush them or throw them into the garbage; instead, consult your pharmacist or local waste management guidelines for safe disposal methods. Keep the medication away from children to prevent accidental use.

Following are the quick tips for Glycerine Suppository:

• Wash your hands thoroughly before and after inserting the suppository.
• Moisten the tip of the suppository with lukewarm water to ease insertion.
• Lie in a comfortable position and gently insert the suppository into the rectum.
• Hold the buttocks together for a few moments to prevent the suppository from slipping out.
• Stay in a lying position for about 15-20 minutes to allow the suppository to dissolve.
• If using for constipation, ensure you drink plenty of fluids to help soften stools.
• Consult your healthcare provider if symptoms persist or worsen after using the suppository.