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Glygol 120ml Syp

Glygol 120ml Syp

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  • Generic Name

    Glyceryl Guaiacolate, Theophylline

Healthwire Pharmacy Ratings & Reviews (1500+)

4.9/ 5
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Product Information

  • Description
  • Ingredients
  • Drug Class
  • Dosage Form
  • Uses
  • In case of Overdose
  • Missed Dose
  • How To Use
  • When Not to Use
  • Side Effects
  • Precautions & Warnings
  • Drug Interactions
  • Food Interactions
  • Storage/Disposal
  • Quick Tips, if any
  • Description

    The mechanism of action of Glyceryl Guaiacolate, also known as guaifenesin, and Theophylline Syrup/Suspension is primarily focused on their expectorant and bronchodilator properties. Guaifenesin works by stimulating the respiratory tract's mucous membranes, reducing the viscosity and stickiness of mucus, and promoting its elimination through coughing. This action helps to clear airways and improve breathing. Theophylline, on the other hand, is a methylxanthine bronchodilator. It relaxes the smooth muscles in the airways, leading to bronchodilation. Theophylline also has mild diuretic and cardiac stimulant effects, but these are not its primary mechanisms of action in respiratory therapy. Together, the combination of guaifenesin and theophylline helps to loosen and clear mucus from the airways, making it easier to breathe, particularly in conditions where excessive mucus production or congestion is a concern.

  • Ingredients

    Glyceryl Guaiacolate, Theophylline

  • Drug Class

    Expectorant, Xanthine derivative.

  • Dosage Form

    Suspension

  • Uses

    The following are the uses of Glyceryl Guaiacolate, Theophylline Syrup/Suspension:

    • Used for treating respiratory conditions like asthma, chronic bronchitis, and emphysema to relax the airways and improve breathing.
    • Used for loosening and thinning mucus in the lungs, making it easier to cough up and clear the airways.
    • Used for reducing inflammation in the respiratory tract, easing breathing difficulties.
    • Used for managing acute exacerbations of chronic obstructive pulmonary disease (COPD) to provide immediate relief.
    • Used for providing short-term relief from symptoms like coughing, wheezing, and shortness of breath.
    • Used for helping patients with respiratory issues to recover from infections or flare-ups.
    • Used for improving exercise tolerance and overall quality of life in individuals with respiratory conditions.
    • Used for aiding in the management of nighttime symptoms, allowing for better sleep.
  • In case of Overdose

    In the case of an overdose of Glyceryl Guaiacolate, Theophylline Syrup/Suspension, prompt medical attention is necessary. Symptoms may include nausea, vomiting, rapid heartbeat, seizures, and in severe cases, respiratory distress. Treatment involves managing these symptoms, providing respiratory support, and potentially administering activated charcoal to prevent further absorption. Medical professionals should be contacted immediately to ensure appropriate care and prevent potential complications.

  • Missed Dose

    In the case of a missed dose of Glyceryl Guaiacolate, Theophylline Syrup/Suspension, it is generally recommended to take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one, as this may increase the risk of side effects. If you frequently miss doses, inform your healthcare provider to discuss alternative dosing options.

  • How To Use

    To administer Glyceryl Guaiacolate, Theophylline Syrup/Suspension, shake the bottle well, measure the prescribed dose with an accurate measuring device, and take it orally, following the dosage instructions provided by your healthcare professional, with or without food, ensuring you adhere to the recommended frequency and amount for your specific needs.

  • When Not to Use

    Here are the conditions and situations when Glyceryl Guaiacolate, Theophylline Syrup/Suspension should not be used:

    • Not suitable for individuals with a known allergy or hypersensitivity to Glyceryl Guaiacolate, Theophylline, or any of the excipients in the syrup or suspension.
    • Contraindicated in patients with a history of seizures or epilepsy, as it may lower the seizure threshold.
    • Should not be used in individuals with stomach ulcers or gastrointestinal bleeding.
    • Not recommended for patients with severe heart conditions, such as recent heart attack or unstable angina.
    • Contraindicated in patients with narrow-angle glaucoma.
    • Not suitable for individuals with liver impairment or severe kidney disease.
    • Should be avoided in patients with hyperthyroidism (overactive thyroid).
    • Not recommended for use in patients with a history of peptic ulcer disease.
    • Contraindicated during breastfeeding, as Theophylline can pass into breast milk and may cause adverse effects in nursing infants.
  • Side Effects

    The side effects of Glyceryl Guaiacolate, Theophylline Syrup/Suspension may include:

    • Nausea and vomiting
    • Stomach pain or discomfort
    • Diarrhea
    • Headache
    • Nervousness or restlessness
    • Rapid or irregular heartbeat (palpitations)
    • Trouble sleeping (insomnia)
    • Skin rash or hives
  • Precautions & Warnings

    Following are the precautions and warnings for Glyceryl Guaiacolate, Theophylline Syrup/Suspension:

    • Do not use in patients with known hypersensitivity or allergy to any of the ingredients in the medication.
    • This medication should be used with caution in patients with a history of stomach ulcers, as it may worsen the condition.
    • It is important to monitor blood theophylline levels regularly, especially in children and elderly patients, to ensure the dose is appropriate and to avoid toxicity.
    • Patients with heart conditions, liver or kidney disease should use this medication with caution and under medical supervision.
    • Avoid excessive alcohol consumption while taking this medication as it may increase the risk of side effects.
    • Do not exceed the recommended dose, as it may lead to serious side effects and toxicity.
    • Pregnant and breastfeeding women should consult their doctor before using this medication, as it may have potential risks to the fetus or infant.
    • Keep out of reach of children and store in a cool, dry place.
  • Drug Interactions

    Following are the drug interactions for Glyceryl Guaiacolate, Theophylline Syrup/Suspension:

    • Theophylline metabolism may be affected by CYP1A2 inhibitors like fluvoxamine, enoxacin, and ciprofloxacin, leading to increased theophylline levels.
    • CYP1A2 inducers such as rifampin, carbamazepine, and smoking can decrease theophylline levels.
    • Theophylline may increase the adverse effects of sympathomimetic agents like epinephrine and ephedrine.
    • It can also enhance the effects of central nervous system stimulants like caffeine.
    • Glyceryl guaiacolate can reduce the absorption of other medications, particularly tetracyclines, digoxin, and phenytoin.
    • Antacids may decrease the absorption of theophylline.
    • Concomitant use of other bronchodilators, such as beta-agonists, may potentiate cardiovascular effects and increase the risk of arrhythmias.
  • Food Interactions

    Following are the food interactions for Glyceryl Guaiacolate, Theophylline Syrup/Suspension:

    • Avoid consuming large amounts of caffeine-containing foods and beverages (like coffee, tea, cocoa, chocolate, energy drinks) as they can increase the side effects of theophylline, leading to potential issues like nausea, vomiting, and insomnia.
    • Grapefruit and grapefruit juice should be consumed with caution as they may increase the levels of theophylline in the blood, possibly causing an irregular heartbeat or other side effects.
    • High-fat meals can delay the absorption of theophylline, potentially affecting its effectiveness. It is best to take the medication on an empty stomach or as directed by your healthcare provider.
    • Avoid excessive consumption of spicy foods, as theophylline may increase stomach acid production and exacerbate the effects of spicy foods, causing heartburn or stomach discomfort.
    • Limit the intake of dairy products, especially milk, as calcium-rich foods can potentially decrease the absorption of theophylline, affecting its effectiveness.
    • Alcohol may increase the risk of side effects and should be consumed in moderation or avoided, especially if you experience dizziness, nausea, or other adverse reactions.
    • Avoid consuming large amounts of sugary foods and drinks, as theophylline can increase blood sugar levels, particularly in individuals with diabetes or pre-existing blood sugar issues.
    • Always follow the instructions provided by your healthcare professional regarding food and medication interactions.
  • Storage/Disposal

    Glyceryl Guaiacolate and Theophylline Syrup/Suspension should be stored in a controlled environment, maintaining a cool temperature between 15-25°C (59-77°F) and protected from direct sunlight and moisture. Ensure the medication is tightly sealed in its original container to maintain its integrity and prevent contamination. Avoid storing it in bathrooms or kitchens, as humidity and temperature fluctuations can impact its effectiveness. Regularly check the expiration date, and when disposing of the medication, do not pour it down the drain or flush it; instead, follow local guidelines for pharmaceutical waste disposal or consult a healthcare professional for guidance on safe disposal practices. Keep the medication securely stored, inaccessible to children, to prevent accidental consumption.

  • Quick Tips, if any

    Following are the quick tips for Glyceryl Guaiacolate and Theophylline Syrup/Suspension:

    • Always follow the dosage instructions provided by your healthcare professional.
    • Shake the bottle vigorously to ensure a homogeneous mixture before each use.
    • Administer the syrup with water; avoid tea, coffee, or dairy for better absorption.
    • Maintain a consistent dosing schedule for optimal therapeutic effect.
    • If stomach irritation occurs, consider taking the syrup with food or after meals.
    • Store the medication safely, away from children, to prevent accidental ingestion.
    • Contact your doctor if you experience any unusual symptoms or side effects.

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