GRAVIDA SOFT GEL CAP

DHA and L-Methylfolate, along with Vitamin B12, work synergistically to support various physiological processes. DHA (Docosahexaenoic Acid), an omega-3 fatty acid, is crucial for brain and eye health, reducing inflammation, and supporting overall cognitive function. L-Methylfolate, the biologically active form of folate (vitamin B9), plays a vital role in DNA synthesis, neurotransmitter production, and homocysteine metabolism, which is essential for cardiovascular and neurological health. Vitamin B12, in its biologically active form, is essential for red blood cell formation, nerve function, and DNA synthesis. Together, these components enhance the bioavailability and effectiveness of each other, promoting optimal cellular function, particularly in the brain and nervous system.

DHA with L-methylofolate 12, vitamin B 12

Methylfolate and B12 supplement.

Capsule

The following are the uses of DHA with L-methylofolate 12, vitamin B 12 Capsule:

• Used for maintaining brain function and cognitive health
• Used for supporting heart health and reducing the risk of cardiovascular diseases
• Used for managing symptoms of depression and mood disorders
• Used for enhancing eye health and preventing age-related macular degeneration
• Used for promoting skin health and reducing inflammation
• Used for supporting fetal brain development during pregnancy
• Used for improving energy levels and reducing fatigue

In the case of an overdose of DHA with L-methylfolate and vitamin B12 capsules, it is important to remain calm and take immediate action. Contact a healthcare professional or poison control center for guidance. They will provide specific instructions based on the severity of the overdose. Common symptoms may include nausea, dizziness, or an increased heart rate. Prompt medical assessment and treatment are essential to ensure the best possible outcome and to prevent any potential long-term effects.

In the case of a missed dose of DHA with L-methylfolate and vitamin B12, it is important to take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one, as this may increase the risk of side effects. It is advisable to set a reminder or use a pill organizer to help you remember to take your medication at the same time each day.

To take the DHA with L-Methylfolate 12, Vitamin B12 capsule, swallow the capsule whole with a glass of water, preferably at the same time each day, following the dosage instructions provided by your healthcare professional, ensuring you do not skip or exceed the recommended dose.

Here are the conditions or situations when DHA with L-Methylfolate 12, Vitamin B12 Capsule should not be taken:

• Not suitable for individuals with a known allergy to DHA (docosahexaenoic acid), L-methylfolate, or vitamin B12 (cyanocobalamin).
• Should not be used in patients with a history of allergic reactions to fish or fish oil products, as DHA is often derived from fish sources.
• Contraindicated in individuals with pernicious anemia, as vitamin B12 deficiency in this condition is due to a lack of intrinsic factor, and oral supplements may not be effective.
• Not recommended for patients with Leber's disease, as they are at risk of optic nerve damage with high doses of vitamin B12.
• Should be used with caution in individuals with kidney disease, as high doses of methylfolate may accumulate and potentially cause adverse effects.
• Not suitable for patients with hyperhomocysteinemia who also have a history of cardiovascular disease, as high doses of vitamin B12 and folate may increase the risk of cardiovascular events.
• Should not be used in patients with untreated folic acid or B12 deficiency anemia, as the combination may mask the underlying deficiency and delay proper diagnosis and treatment.

The possible side effects of DHA with L-Methylfolate and Vitamin B12 Capsule may include:

• Nausea or upset stomach
• Diarrhea or loose stools
• Stomach cramps
• Headache or dizziness
• Skin rash or itching
• Nervousness or anxiety
• Sleep disturbances
• Mild allergic reactions such as itching or hives.

Following are the precautions and warnings for DHA with L-methylfolate and Vitamin B12 Capsule:

• This medication should not be taken if you have a known allergy to any of its components, including fish, as some formulations may contain fish oil.
• Patients with a history of bleeding disorders or those taking blood-thinning medications should exercise caution, as DHA can affect blood clotting.
• Those with a history of gastrointestinal disorders should be monitored, as high doses of DHA may cause gastrointestinal side effects.
• Caution is advised for individuals with diabetes, as L-methylfolate may impact blood sugar levels.
• Vitamin B12 may mask symptoms of polycythemia vera, a blood disorder, so regular monitoring is necessary.
• Do not exceed the recommended dosage, as high doses of B vitamins may lead to adverse effects.
• Consult a healthcare professional if you are pregnant, breastfeeding, or planning to become pregnant, as these supplements may require specific adjustments during these periods.

Following are the drug interactions for DHA with L-Methylfolate and Vitamin B12:

• No significant interactions have been reported between DHA and L-methylfolate, but concurrent use may require additional monitoring due to their potential effects on homocysteine metabolism.
• DHA can increase the anticoagulant effect of Vitamin B12, leading to a higher risk of bleeding. Regular blood tests are advised.
• L-Methylfolate might decrease the effectiveness of certain medications, including methotrexate, phenobarbital, phenytoin, and primidone, requiring dosage adjustments.
• Vitamin B12 supplementation may reduce the efficacy of medications for bacterial infections, such as chloramphenicol and tetracyclines.
• Antacids containing aluminum or calcium can decrease the absorption of DHA and Vitamin B12, reducing their effectiveness.
• Drugs that affect the absorption of fats, like orlistat, may lower the absorption of DHA, requiring dosage adjustments.
• Caution is advised when combining DHA with blood thinners, as it may further increase the risk of bleeding.

Following are the food interactions for DHA with L-Methylfolate and Vitamin B12:

• Fatty fish like salmon, mackerel, and sardines can enhance the effects of DHA as they are rich in omega-3 fatty acids, providing a complementary effect.
• Leafy green vegetables and legumes, which are rich in folate, can support the action of L-Methylfolate by ensuring adequate folate levels in the body.
• Fortified cereals and grains, often enriched with Vitamin B12, can work synergistically with the supplement, especially for individuals with dietary restrictions.
• Eggs, a good source of choline, can interact positively with DHA, supporting overall brain health.
• Avoid excessive alcohol consumption as it may interfere with the absorption of Vitamin B12 and DHA, potentially reducing their effectiveness.
• Processed foods high in trans fats may counteract the benefits of DHA and should be limited.
• Consuming a balanced diet with a variety of whole foods can optimize the benefits of these supplements, ensuring better absorption and utilization of nutrients.

Storage and disposal of DHA with L-Methylfolate 12, Vitamin B12 Capsules should be done with careful consideration. Store the capsules in a cool and dry place, away from direct sunlight and moisture, preferably at room temperature. Keep the medication in its original container, tightly sealed, to maintain its integrity. Avoid exposing the capsules to extreme temperatures by not storing them near heat sources. Regularly check the expiration date, and dispose of any unused or expired medication responsibly. Do not dispose of the capsules via household waste or drainage systems; consult a pharmacist for guidance on appropriate disposal methods. Ensure the medication is kept securely away from children to prevent accidental consumption.

Following are the quick tips for DHA with L-Methylfolate 12, Vitamin B12 Capsule:

• Consult your doctor before taking this supplement to ensure it's suitable for your health needs.
• Swallow the capsule whole with a full glass of water for easy consumption.
• Maintain a consistent daily routine by taking the capsule at the same time each day.
• Consider taking the capsule with a meal to enhance absorption and reduce the risk of stomach upset.
• Store the capsules in a cool, dry place, away from direct sunlight and moisture.
• Do not crush or chew the capsule; it is designed to be swallowed whole.
• Keep a record of your daily intake to ensure you're following the recommended dosage.
• Inform your healthcare provider if you are taking any other medications to ensure compatibility.