Gvia-M XR (100/1000mg) 14 Tablets

Sitagliptin works by inhibiting the breakdown of incretins, hormones that regulate blood sugar levels. By keeping these hormones in the bloodstream longer, insulin production is stimulated only when blood sugar levels are elevated, effectively reducing blood sugar levels in patients with type 2 diabetes mellitus. Metformin is a drug that belongs to the biguanide class, and it works by reducing glucose production in the liver and increasing glucose absorption by skeletal muscles. Unlike other drugs for managing type 2 diabetes, Metformin does not increase insulin secretion from the pancreas. This feature helps reduce the excessive workload on the pancreas, which is particularly beneficial for those whose pancreas is producing less insulin or whose bodies are resistant to insulin effects.

Metformin:

Unveiling its multifaceted uses and transformative applications as follows:

• Sitagliptin 100mg is used alongside diet and exercise in adults with type 2 diabetes to help lower blood sugar.
• Metformin Hydrochloride 1000mg is also used alongside diet and exercise in adults with type 2 diabetes to help lower blood sugar.

Tailoring Treatment for Optimal Health, Prescribed Medication Dosage is:

• For Sitagliptin 100mg-
• Take one tablet with food as a single daily dose.
• Full effect of Sitagliptin may not be seen during the first few weeks of treatment
• Continue using it as directed by your physician
• For Metformin Hydrochloride 1000mg-
• Take with a meal to reduce the risk of stomach upset
• Dosage depends on your medical condition, response to treatment, and age
• This medication is to be taken orally, swallowed whole with water or liquid. Do not crush or chew the tablet.

An overdose of sitagliptin and metformin can lead to various severe symptoms. It is crucial to seek immediate medical attention if you suspect an overdose of these medications. The appropriate treatment varies depending on the individual's symptoms and liver and kidney function, which is why medical attention is essential.The treatment may involve the use of medications such as activated charcoal, to help absorb the drugs and prevent their absorption into the bloodstream. However, in more severe cases, dialysis or a liver flush may be required to remove the drugs from the body. The specific treatment approach will depend on the individual's symptoms, the severity of the overdose, and their medical history. It is important to consult with a medical professional for appropriate treatment guidance.

It is important to take your medication as soon as possible if you miss a dose, unless it is nearly time for your next scheduled dose. If you miss a dose by only a small amount of time, it is typically best to skip that dose and return to your regular dosing schedule. It is advised that you do not double up on medication doses unless you have consulted with your healthcare provider and they have advised you to do so. For optimal guidance regarding missed doses, it is recommended that you consult with a healthcare professional, who can provide you with personalized advice.

When taking Sitagliptin 100mg and Metformin Hydrochloride 1000mg, it's essential to follow your doctor's instructions specifically as they may vary depending on your needs. Here are some general guidelines:

Discerning instances where this medication may not be appropriate:

• Metformin is a biguanide drug that works by reducing glucose production in the liver and increasing glucose uptake in skeletal muscle, while Sitagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor that enhances insulin secretion and decreases glucagon secretion. Using both drugs together may lead to overlapping effects and complicate the management of diabetes forAchieving Desired Glucose Control.
• Combining multiple medications can make it more difficult to achieve the desired glucose control and can also make it harder to identify the cause of adverse effects or changes in glucose levels. It is important to discuss your concerns with your regular provider, pharmacist, or diabetes educator to get personalized advice.

Unraveling the side effects lurking behind this medications are as follows:

• Nausea, vomiting, stomach pain, diarrhea, and loss of appetite

• Metallic taste in the mouth

• Thirst and frequent urination

• Weakness and dizziness
• Tiredness
• Dry mouth
• Chronic indigestion, or heartburn
• Intestinal yeast infection (such as thrush)
• Skin reactions, such as rash, itching, redness, and swelling
• Gulf War syndrome (tendons and other connective tissues swelling)
• Lactic Acidosis

Both Sitagliptin 100mg and Metformin Hydrochloride 1000mg are prescribed to patients with Type 2 diabetes to help regulate blood sugar levels. They each work differently in managing blood sugar levels:

When taking Sitagliptin and Metformin Hydrochloride, it is likely that you will need regular laboratory monitoring to check for any negative side effects and to ensure the medication is working properly. Firstly, blood sugar levels will be monitored to ensure that your body is responding well to the medications, avoiding hypoglycemia (low blood sugar) or hyperglycemia (high blood sugar). Secondly, kidney function tests will be completed regularly to monitor for any kidney damage or decreased kidney function as Metformin is excreted by the kidneys. Thirdly, due to the chance of hyperlipidemia occurring, it is crucial to monitor your cholesterol and triglyceride levels to assess whether there is a need for concurrent lipid-lowering therapy. Lastly, the Hemoglobin A1C test provides an average of your blood sugar levels over the past few months, allowing your doctor to assess how well your body is processing the medication and controlling your diabetes. Your doctor will advise on how often you should be undergoing these tests, ranging from monthly to semi-annually, depending on the outcome of the tests and the stability of your condition. It is important to disclose any adverse effects or changes to your health as this may impact your lab testing schedule and potential medication adjustments.