D3 HD 200 (200IU) 5ml Oral Drops

Cholecalciferol, also known as vitamin D3, primarily works by playing a crucial role in maintaining calcium homeostasis in the body. Its mechanism of action involves multiple steps. Firstly, cholecalciferol is converted in the liver to 25-hydroxycholecalciferol (calcidiol), which is further metabolized in the kidneys to its active form, 1,25-dihydroxycholecalciferol (calcitriol). Calcitriol acts as a hormone, binding to vitamin D receptors (VDRs) found in various tissues, including the intestines, bones, and kidneys. This binding activates specific genes, leading to increased intestinal absorption of calcium and phosphorus, promoting bone mineralization, and regulating parathyroid hormone (PTH) secretion, which in turn influences calcium and phosphate levels in the blood. By enhancing calcium absorption and utilization, cholecalciferol contributes to the development and maintenance of healthy bones and teeth.

Cholecalciferol 200iu

Vitamin D3.

Drop

The following are the uses of Cholecalciferol 200iu Drop:

• Used for treating and preventing Vitamin D deficiency
• Used to maintain healthy bones and teeth
• Used in the absorption of calcium and phosphorus
• Used for individuals with limited sun exposure
• Used to support immune system health
• Used to reduce the risk of respiratory infections
• Used in the elderly to improve muscle strength and balance
• Used to support overall well-being and bone health

In the case of an overdose of Cholecalciferol 200iu Drops, it is important to seek medical advice promptly. Symptoms of overdose may include nausea, vomiting, constipation, and in severe cases, kidney damage. The effects can vary depending on the individual's age, weight, and overall health. Prompt medical intervention is necessary to manage and treat any adverse effects, ensuring the best possible outcome for the patient.

In the case of a missed dose of Cholecalciferol 200iu Drops, it is important to administer the medication as soon as you remember. However, if it is almost time for the next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one. If you miss multiple doses, consult your healthcare professional for advice on how to adjust your dosing schedule and ensure you maintain the recommended vitamin D levels.

To administer Cholecalciferol 200iu Drops, gently squeeze the desired number of drops (as prescribed) under the tongue and hold for a brief moment to allow for absorption, following the instructions provided by your healthcare professional or as directed on the product packaging.

Here are the situations when Cholecalciferol 200iu Drop should not be used:

• Do not use if you have a known allergy to Cholecalciferol or any of its ingredients.
• Avoid using this medication if you have high levels of calcium or vitamin D in your blood.
• Not suitable for individuals with kidney stones or a history of kidney disease.
• Should not be used in patients with hypervitaminosis D (vitamin D toxicity).
• Contraindicated in individuals with conditions that cause calcium buildup in tissues (e.g., hypercalcemia, metastatic calcification).
• Not recommended for those with sarcoidosis, as it can increase calcium levels.
• Do not use if you have Williams syndrome, a genetic disorder affecting calcium regulation.

The side effects of Cholecalciferol 200iu Drop may include:

• Nausea and vomiting.
• Constipation or diarrhea.
• Dry mouth.
• Metallic taste in the mouth.
• Fatigue and muscle weakness.
• Bone and joint pain.
• Increased calcium levels in the blood (hypercalcemia), which can lead to kidney problems.
• Allergic reactions, such as rash, itching, or difficulty breathing.

Following are the precautions and warnings for Cholecalciferol 200iu Drops:

• Avoid if allergic to any ingredients in the drops or if you have a known hypersensitivity to vitamin D.
• Individuals with kidney disease, high blood calcium levels, or conditions causing high vitamin D levels should use with caution and under medical supervision.
• Regular monitoring of calcium levels is recommended during long-term use.
• Do not exceed the recommended dosage as it may lead to vitamin D toxicity.
• If you are taking other vitamin D supplements or medications, consult a healthcare professional to avoid potential interactions.
• Keep out of reach of children. Accidental ingestion may cause serious side effects.
• Store in a cool, dry place, away from direct sunlight.

Following are the drug interactions for Cholecalciferol 200iu Drop:

• Anticonvulsants like phenobarbital, phenytoin, and carbamazepine may reduce the effectiveness of Cholecalciferol by increasing its metabolism.
• Cholestyramine and colestipol can decrease the absorption of vitamin D, leading to reduced effectiveness.
• Thiazide diuretics can increase the risk of hypercalcemia when used with Cholecalciferol, especially in patients with renal impairment.
• Calcium channel blockers, such as verapamil and diltiazem, may increase vitamin D levels and should be used cautiously.
• Orlistat, a weight-loss medication, can reduce the absorption of fat-soluble vitamins, including vitamin D.
• Corticosteroids like prednisone can increase vitamin D metabolism and decrease calcium absorption, potentially requiring higher doses of Cholecalciferol.
• Ketoconazole, a potent CYP3A4 inhibitor, may increase vitamin D levels by reducing its metabolism.
• Concurrent use with other vitamin D supplements or calcium-containing products should be monitored to avoid excessive vitamin D intake.

Following are the food interactions for Cholecalciferol 200iu Drop:

• Consuming foods rich in Vitamin D like fatty fish (salmon, mackerel), egg yolks, and fortified dairy products can enhance the effects of Cholecalciferol, but excessive intake may lead to Vitamin D toxicity.
• Grapefruit juice can interfere with the absorption of Vitamin D, leading to reduced effectiveness of Cholecalciferol.
• High-fiber foods like whole grains, legumes, and certain vegetables can affect the absorption of fat-soluble vitamins like Vitamin D, potentially reducing its bioavailability.
• Avoid excessive alcohol consumption as it may interfere with Vitamin D metabolism and impair calcium absorption, potentially reducing the benefits of Cholecalciferol.
• Calcium-rich foods like dairy products, leafy greens, and fortified foods should be consumed in moderation as excessive calcium intake may interact with Vitamin D metabolism.
• Vitamin K-rich foods such as leafy green vegetables, broccoli, and Brussels sprouts can be beneficial as they support bone health and work synergistically with Vitamin D.
• Maintain a balanced diet with a variety of foods to ensure optimal absorption and utilization of Cholecalciferol and other essential nutrients.

Cholecalciferol 200iu Drop should be stored in a cool and dry place, preferably at room temperature (around 25°C), away from direct sunlight and moisture. Keep the dropper bottle tightly sealed in its original packaging to maintain its integrity and prevent contamination. Avoid storing it in the bathroom cabinet or near any heat-emitting appliances, as extreme temperatures can degrade the medication. Pay attention to the expiration date, and discard any unused or expired drops safely. Improper disposal methods like flushing or pouring down the drain should be avoided; instead, consult a pharmacist or healthcare professional for guidance on appropriate disposal practices. Additionally, ensure the medication is kept out of children's reach to prevent accidental consumption.

Following are the quick tips for Cholecalciferol 200iu Drop:

• Consult your doctor or pharmacist for dosage instructions specific to your health needs.
• Administer the drops as directed by your healthcare provider, usually once daily or as prescribed.
• Ensure the drops are placed directly into the mouth or mixed with food as advised.
• For infants, the drops can be placed on the tongue or mixed with breast milk or formula.
• For children and adults, the drops can be taken orally or mixed with food or drinks as recommended.
• Store the drops in a cool, dry place, away from direct sunlight and moisture.
• Keep the medication out of reach of children to prevent accidental ingestion.