HEPATOCARE CAP 20S (NUTRA WAY)

Calcium Citrate Malate is a calcium salt composed of calcium ions and citrate and malate anions. When ingested, it dissociates into its constituent ions in the digestive tract. Calcium ions are absorbed in the small intestine, primarily in the duodenum and jejunum, through two main mechanisms active transcellular absorption and passive paracellular absorption. Active absorption involves the binding of calcium ions to a calcium-binding protein called calbindin, which is facilitated by vitamin D. This complex is then transported across the intestinal epithelial cells into the bloodstream. Passive absorption occurs through the tight junctions between cells, driven by the concentration gradient. Citrate and malate anions enhance calcium absorption by forming soluble complexes with calcium ions, increasing solubility and facilitating its transport across the intestinal barrier. Once absorbed, calcium is primarily utilized for bone mineralization, muscle function, nerve transmission, and various enzymatic processes throughout the body.

Calcium Citrate Malate

Calcium Salts.

Capsule

The following are the uses of Calcium Citrate Malate Capsule:

• Used for preventing and treating calcium deficiencies.
• Used to support bone health and strength, particularly in individuals with conditions like osteoporosis.
• Used for promoting proper muscle function and nerve signaling.
• Used to enhance calcium absorption, as it is a highly bioavailable form of calcium.
• Used for maintaining healthy teeth and gums.
• Used to alleviate symptoms of conditions like rickets or osteomalacia.
• Used as a dietary supplement for individuals with calcium-deficient diets.

In the case of an overdose of Calcium Citrate Malate Capsule, it is important to recognize the signs, which may include nausea, vomiting, and extreme thirst. If you suspect an overdose, contact a healthcare professional immediately. They can provide guidance on the necessary steps, which may include inducing vomiting or administering specific treatments to counteract the effects of the overdose. Prompt action can help mitigate potential health risks associated with excessive calcium intake.

In the case of a missed dose of Calcium Citrate Malate Capsule, it is generally advised to take the missed dose as soon as you remember. However, if it's almost time for your next scheduled dose, it's best to skip the missed dose and continue with your regular dosing schedule. Avoid taking a double dose to make up for a missed one, as this may increase the risk of side effects. If you frequently miss doses, consider setting reminders or using a pill organizer to help you stay on track with your medication regimen. Always consult your healthcare provider if you have any concerns or questions about missed doses.

To take Calcium Citrate Malate Capsule, swallow the capsule whole with a full glass of water, preferably during a meal or as directed by your healthcare provider, ensuring that you follow the prescribed dosage and schedule provided.

Following are the conditions or circumstances when Calcium Citrate Malate Capsule should not be taken:

• Do not take if you have a known allergy or hypersensitivity to calcium citrate, calcium malate, or any of the inactive ingredients in the capsule.
• Avoid using this supplement if you have high levels of calcium in your blood (hypercalcemia) or severe kidney disease.
• Not suitable for individuals with a history of kidney stones.
• Should not be used in individuals with conditions that impair calcium absorption or those with conditions requiring low calcium intake.
• Contraindicated for patients with parathyroid gland disorders or conditions affecting bone metabolism.
• Do not take this supplement if you are bedridden or unable to move around freely, as this can increase the risk of calcium-related complications.
• Not recommended for individuals with sarcoidosis, as it can affect calcium metabolism.
• Avoid using this supplement if you are taking other calcium-containing medications or supplements without consulting a healthcare professional.

The side effects of Calcium Citrate Malate Capsule may include:

• Constipation
• Stomach pain or upset
• Nausea and vomiting
• Dry mouth
• Increased thirst
• Frequent urination
• Fatigue and muscle weakness
• Bone and joint pain

Following are the precautions and warnings for Calcium Citrate Malate Capsule:

• Avoid using this supplement if you have a known allergy or sensitivity to calcium citrate malate or any of its ingredients.
• Consult your doctor if you have a history of kidney stones, as calcium supplements may increase the risk of stone formation.
• Individuals with gastrointestinal disorders should use with caution, as high doses of calcium can cause constipation or other digestive issues.
• If you are taking other medications, inform your healthcare provider, as calcium can interact with certain drugs, affecting their absorption.
• Do not exceed the recommended dosage, as excessive calcium intake can lead to hypercalcemia and other health complications.
• Keep out of reach of children. Store in a cool, dry place, away from direct sunlight.
• Pregnant and breastfeeding women should consult their healthcare professional before taking this or any other supplement.

Following are the drug interactions for Calcium Citrate Malate Capsule:

• May reduce the absorption of tetracycline antibiotics, such as doxycycline, when taken simultaneously.
• Bisphosphonates like alendronate may have decreased absorption when used with calcium supplements.
• Thiazide diuretics, including hydrochlorothiazide, can increase calcium retention, leading to potential hypercalcemia.
• Calcium can decrease the absorption of levothyroxine, requiring a 4-hour interval between the two medications.
• Calcium supplements may reduce the effectiveness of phenytoin, an anticonvulsant, by decreasing its absorption.
• Can reduce the absorption of certain iron supplements, especially when taken simultaneously.
• May interfere with the absorption of zinc supplements, particularly when taken together.

Following are the food interactions for Calcium Citrate Malate Capsule:

• Calcium-rich foods like dairy products (milk, cheese, yogurt), leafy greens, and fortified foods can enhance calcium absorption and improve bone health when taken with the capsule.
• Consuming foods high in oxalic acid (spinach, rhubarb, sweet potatoes) or phytic acid (whole grains, legumes) can hinder calcium absorption, so it's best to eat them separately from calcium supplements.
• Vitamin D-rich foods such as fatty fish, egg yolks, and fortified dairy products can aid in calcium absorption and utilization, promoting better bone health.
• Avoid excessive intake of high-fiber foods like whole grains and legumes immediately before or after taking the capsule, as fiber can interfere with mineral absorption.
• Caffeine-rich beverages like coffee and tea may decrease calcium absorption, so it's advisable to limit their consumption around the time of taking the supplement.
• Alcohol should be consumed in moderation as it can impair calcium absorption and negatively impact bone health over time.
• Maintaining a balanced diet with a variety of fruits, vegetables, lean proteins, and healthy fats can optimize the benefits of calcium supplementation and overall health.

Calcium Citrate Malate Capsules should be stored in a cool and dry environment, preferably at room temperature, ensuring protection from direct sunlight and moisture. The original packaging should be tightly sealed to maintain its integrity and prevent contamination. It is crucial to store the capsules away from heat-emitting appliances or radiators to preserve their effectiveness. Regularly check the expiration date, and if the product has passed its expiry, dispose of it carefully, avoiding methods like flushing or pouring into drains. Consult your pharmacist for appropriate disposal practices to minimize environmental impact. Keep the capsules out of children's reach to prevent accidental consumption.

Following are the quick tips for Calcium Citrate Malate Capsule:

• Swallow the capsule whole with a full glass of water to aid in swallowing and absorption.
• Take it with food for better absorption and to prevent stomach upset.
• Maintain a consistent daily routine for optimal calcium absorption.
• Consider splitting the dose if recommended by your doctor for better tolerance.
• Avoid taking other medications or supplements within 2 hours of taking this capsule.
• Do not chew or crush the capsule, as it may affect the effectiveness.
• Regularly monitor your calcium levels if taking this supplement long-term.
• Store the capsules in a cool, dry place, away from direct sunlight.