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Somatropin, also known as human growth hormone (hGH), acts by binding to growth hormone receptors on various cells and tissues throughout the body. Once bound, it stimulates cellular processes involved in growth and development. The mechanism of action involves the activation of intracellular signaling pathways, primarily the JAK-STAT pathway, which leads to increased protein synthesis, cell proliferation, and the expression of genes related to growth. Somatropin promotes linear growth in children by stimulating the growth of cartilage and bone, and it also enhances protein production, leading to increased muscle mass and tissue repair. Additionally, it influences metabolism by regulating fat utilization and promoting lipolysis, thereby reducing fat accumulation.
Growth hormone
Injection
The following are the uses of Somatropin injection:
In the case of an overdose of Somatropin injection, it is important to recognize the potential signs and symptoms, which may include swelling, joint and muscle pain, and elevated blood sugar levels. Promptly seek medical advice if you suspect an overdose, as timely intervention can help manage the adverse effects. Treatment for overdose may involve supportive care and monitoring of vital signs, as well as addressing any specific symptoms that arise. It is crucial to act quickly to minimize the impact of an overdose.
In the case of a missed dose of Somatropin injection, it is important to follow the guidelines provided by your healthcare professional. If you realize you've missed a dose, administer it as soon as possible on the same day. However, if it's almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not administer a double dose to make up for a missed one. Consult your doctor or pharmacist if you have any concerns or questions about missed doses.
To administer the Somatropin injection, clean the injection site with an alcohol wipe, insert the needle at a 45-degree angle, inject the medication slowly as directed, and then gently withdraw the needle while applying pressure with a sterile cotton ball if needed to prevent bleeding.
Following are the conditions or circumstances when Somatropin injection should not be administered:
The side effects of Somatropin injection may include:
Following are the precautions and warnings:
Following are the drug interactions for Somatropin injection:
Following are the food interactions with Somatropin injection:
Somatropin injection should be stored in a refrigerator at a temperature between 2°C and 8°C (36°F and 46°F). It is crucial to keep the injection in its original carton to protect it from light and moisture. Do not freeze the medication as it may affect its potency. Once the vial or cartridge is opened, it should be used immediately, and any unused portion should be discarded properly. For disposal, do not throw away Somatropin injection in regular household trash; instead, follow local guidelines for the safe disposal of medications, or consult a pharmacist for guidance on returning unused or expired medication to a take-back program or healthcare facility. Keep the medication out of the sight and reach of children to prevent accidental use.
Following are the quick tips for Somatropin injection:
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