Hi-Salz 75g Toothpaste

Sodium chloride in the toothpaste formulation functions as an osmotic agent, creating an environment that helps to draw out excess fluid from inflamed or swollen oral tissues. This action can aid in reducing gum swelling and promoting healing. Tranexamic acid, on the other hand, is a potent antifibrinolytic agent that works by inhibiting the activation of plasminogen to plasmin, thereby stabilizing fibrin clots and reducing bleeding. By incorporating a small concentration of tranexamic acid (0.05% w/w), the toothpaste can help control minor bleeding from gums or minor oral injuries, contributing to improved oral health and comfort.

Antifibrinolytic, Osmotic agent

Toothpaste

The following are the uses of Sodium chloride, Tranexamic Acid B.P. 0.05% w/w Toothpaste:

• Used for preventing bleeding from small blood vessels in the mouth.
• Used for reducing gum inflammation and promoting healing after oral surgery or dental procedures.
• Used for controlling minor bleeding from tooth extraction sites.
• Used for maintaining oral hygiene and reducing plaque formation.
• Used for freshening breath and providing a clean mouth feel.
• Used for gentle cleansing and soothing irritated gums.
• Used for long-lasting protection against tooth decay and enamel erosion.

In the case of an overdose of Sodium Chloride, symptoms may include excessive thirst, swelling, and in severe cases, seizures. For Tranexamic Acid B.P. 0.05% w/w Toothpaste, overdose can lead to gastrointestinal disturbances, nausea, and vomiting. If either of these overdoses is suspected, seek medical advice promptly. Timely intervention can help manage symptoms and prevent potential complications.

In the case of a missed dose of Sodium Chloride, apply the toothpaste as soon as you remember, but if it's almost time for your next dose, skip the missed dose and continue with your regular schedule. For Tranexamic Acid B.P. 0.05% w/w Toothpaste, if you miss a dose, use it as soon as you can. However, if it's almost time for your next application, skip the missed dose and continue with your regular application schedule. Do not use extra toothpaste to make up for a missed dose.

To use Sodium Chloride, Tranexamic Acid B.P. 0.05% w/w Toothpaste, apply a pea-sized amount onto a soft-bristled toothbrush, brush your teeth gently for at least 2 minutes, and rinse thoroughly with water.

Following are the conditions or situations when Sodium Chloride, Tranexamic Acid B.P. 0.05% w/w Toothpaste should not be used:

• Allergy or hypersensitivity to sodium chloride, tranexamic acid, or any of the toothpaste's ingredients.
• Patients with active bleeding disorders or those taking anticoagulant medications.
• Individuals with uncontrolled high blood pressure (hypertension).
• Not suitable for individuals with a history of thromboembolic events or conditions such as deep vein thrombosis or pulmonary embolism.
• Should not be used in patients with kidney disease or impaired kidney function.
• Contraindicated during active dental or gum infections until the infection is treated.
• Not recommended for use in children without medical supervision.
• Avoid if you have a history of blood clots or stroke.

The side effects of Sodium Chloride, Tranexamic Acid B.P. 0.05% w/w Toothpaste may include:

• Gum irritation or inflammation
• Tooth sensitivity
• Mouth sores or ulcers
• Altered taste perception
• Dry mouth
• Increased bleeding tendency (in rare cases)
• Allergic reactions,rash, itching, swelling of the lips or tongue

Following are the precautions and warnings for Sodium Chloride, Tranexamic Acid B.P. 0.05% w/w Toothpaste:

• Avoid contact with eyes; in case of accidental contact, rinse thoroughly with water.
• Do not swallow the toothpaste; it is for external oral use only.
• Keep out of reach of children; supervise children while brushing to prevent ingestion.
• Not suitable for individuals with a known allergy to tranexamic acid or any other ingredients in the toothpaste.
• Consult a dentist if you have any oral health concerns or conditions before using this toothpaste.
• Discontinue use if irritation, redness, or any adverse reaction occurs and consult a healthcare professional.
• Store in a cool, dry place, away from direct sunlight and extreme temperatures.

Following are the drug interactions for Sodium chloride, Tranexamic Acid B.P. 0.05% w/w Toothpaste:

• No significant interactions have been reported with sodium chloride when used topically in toothpaste.
• Tranexamic acid may interact with anticoagulants, increasing the risk of thromboembolic events. Close monitoring is advised.
• Concomitant use of procoagulant medications should be avoided as it may enhance the risk of clot formation.
• Antifibrinolytic agents like aminocaproic acid can have additive effects when used with tranexamic acid.
• Drugs affecting renal function may influence the clearance of tranexamic acid, requiring dosage adjustments.
• It may reduce the effectiveness of hormonal contraceptives, requiring additional contraceptive measures.
• Use with caution in patients taking antihypertensive medications, as tranexamic acid may increase blood pressure.
• Some antibiotics, such as tetracyclines, may have their absorption reduced when taken with tranexamic acid.

Following are the food interactions for Sodium chloride, Tranexamic Acid B.P. 0.05% w/w Toothpaste:

• Avoid consuming excessive salty foods as Sodium Chloride is a salt compound, and high salt intake can lead to increased blood pressure and water retention.
• Acidic foods like citrus fruits and tomatoes might cause a slight stinging sensation when used with Tranexamic Acid toothpaste.
• It is best to avoid foods or drinks with high sugar content, as sugar can promote bacterial growth in the mouth.
• Toothpaste should be used after meals, especially if consuming staining foods like coffee, tea, or colored beverages.
• Avoid eating or drinking for at least 30 minutes after brushing to prevent washing away the protective fluoride and Tranexamic Acid.
• Dairy products like milk and cheese can help neutralize the acid in the mouth, which can be beneficial after using the toothpaste.
• Green leafy vegetables, rich in Vitamin K, should be consumed as part of a balanced diet, as Tranexamic Acid can interfere with Vitamin K absorption.

Sodium Chloride and Tranexamic Acid B.P. 0.05% w/w Toothpaste should be stored in a cool, dry area, preferably at room temperature, ensuring protection from direct sunlight and moisture. The toothpaste tube should be securely sealed after each use to maintain its integrity and prevent contamination. Avoid exposing the toothpaste to extreme temperatures, including heat sources like ovens or radiators, as this may impact its effectiveness. Dispose of the toothpaste responsibly by consulting a pharmacist or local waste management guidelines for appropriate methods, and never pour it down the drain or flush it. Keep the toothpaste securely stored, out of the reach of children, to prevent accidental ingestion.

Following are the quick tips for Sodium Chloride and Tranexamic Acid B.P. 0.05% w/w Toothpaste:

• Brush your teeth as directed by your dentist or healthcare professional for optimal oral care.
• Use a pea-sized amount of toothpaste on your toothbrush for effective cleaning.
• Brush your teeth twice daily for at least 2 minutes each time.
• Ensure you brush all surfaces of your teeth, including the front, back, and chewing surfaces.
• Spit out the toothpaste after brushing, and avoid swallowing it.
• Store the toothpaste at room temperature, away from direct sunlight.
• Keep the toothpaste out of reach of children to prevent misuse.