Hiace (1.25mg) 28 Tablets

Ramipril 25MG Tablet, a potent angiotensin-converting enzyme (ACE) inhibitor, primarily exerts its therapeutic effects by inhibiting the ACE enzyme. This inhibition prevents the conversion of angiotensin I to angiotensin II, a potent vasoconstrictor. Consequently, the reduced levels of angiotensin II lead to decreased vasoconstriction and aldosterone secretion, resulting in lowered blood pressure. Additionally, the suppression of ACE enhances the levels of bradykinin, a vasodilator, further contributing to the overall vasodilation and improved blood flow. This mechanism of action makes Ramipril effective in treating hypertension and other cardiovascular conditions.

ACE inhibitor.

Tablet

The following are the uses of Ramipril 25MG Tablet:

• Used for treating high blood pressure, helping to prevent heart attacks and strokes.
• Used to improve survival rates after a heart attack.
• Used to manage heart failure by reducing strain on the heart.
• Used to slow down the progression of kidney damage in certain conditions.
• Used to reduce protein loss in urine for those with diabetes and kidney issues.
• Used to prevent diabetic retinopathy, a diabetes-related eye condition.
• Used to lower the risk of cardiovascular events like heart attacks or strokes in high-risk individuals.
• Used to improve overall cardiovascular health and manage associated conditions.

In the case of an overdose of Ramipril 25MG tablets, the patient may experience symptoms such as severe dizziness, fainting, and a significant drop in blood pressure. This can lead to potential kidney failure, electrolyte imbalances, and even cardiac events. It is crucial to seek medical assistance promptly if an overdose is suspected. The healthcare provider may recommend immediate actions such as inducing vomiting or administering activated charcoal to prevent further absorption of the medication.

In the case of a missed dose of Ramipril 25MG Tablet, it is important to take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one, as this may increase the risk of side effects. If you frequently miss doses, consider setting reminders or using a pill organizer to help you stay on track with your medication regimen. Consult your healthcare provider if you have any concerns or questions about managing missed doses.

To take Ramipril 25MG Tablet, swallow the tablet whole with a glass of water, preferably at the same time each day, as directed by your healthcare professional, who will determine the appropriate dosage based on your medical condition.

Following are the conditions or situations when Ramipril 25MG Tablet should not be taken:

• Should not be used in individuals with a known allergy to Ramipril or any ACE (angiotensin-converting enzyme) inhibitors.
• Contraindicated in pregnant women, especially during the second and third trimesters.
• Not recommended for breastfeeding mothers as it can pass into breast milk.
• Should be avoided in individuals with a history of angioedema, whether it is related to previous ACE inhibitor therapy or not.
• Do not use if you have a condition called aortic stenosis (narrowing of the aortic heart valve).
• Not suitable for individuals with bilateral renal artery stenosis (narrowing of the arteries supplying the kidneys).
• Should not be used immediately after a kidney transplant.
• Avoid if you have severe liver disease or liver problems.
• Contraindicated in patients undergoing desensitization therapy to reduce an allergic response to bee or wasp stings.

The side effects of Ramipril 25MG Tablet may include:

• Dizziness or lightheadedness
• Fatigue or weakness
• Dry cough
• Headache
• Nausea and vomiting
• Diarrhea or abdominal pain
• Skin rash or itching
• Changes in taste sense

Following are the precautions and warnings for Ramipril 25MG Tablet:

• Patients with a known allergy to Ramipril or other ACE inhibitors should not take this medication.
• Close monitoring of kidney function is necessary, especially in patients with existing kidney disease or those at risk of renal impairment.
• Caution is advised for patients with a history of liver problems, as Ramipril may affect liver function.
• It may cause dizziness or lightheadedness, particularly when standing up suddenly; patients should exercise caution to avoid falls.
• Diabetic patients should be aware that Ramipril may cause an increase in blood sugar levels.
• Patients undergoing surgery or anesthesia should inform their healthcare provider about Ramipril use.
• Pregnant or breastfeeding women should consult their doctor as Ramipril may cause harm to the fetus or infant.

Following are the drug interactions for Ramipril 25MG Tablet:

• Concurrent use with diuretics (e.g., thiazide diuretics) may increase the risk of hypotension and renal impairment, requiring close monitoring of blood pressure and kidney function.
• The combination of Ramipril with other angiotensin-converting enzyme (ACE) inhibitors or angiotensin receptor blockers (ARBs) can lead to excessive blood pressure reduction and increased risk of renal dysfunction.
• Taking Ramipril with potassium-sparing diuretics or potassium supplements may result in hyperkalemia, a condition of elevated potassium levels in the blood.
• Nonsteroidal anti-inflammatory drugs (NSAIDs) may reduce the antihypertensive effect of Ramipril and increase the risk of renal toxicity.
• Lithium levels can be increased when used with Ramipril, requiring close monitoring to prevent lithium toxicity.
• Antidiabetic medications, such as insulin or oral hypoglycemic agents, may have their effects enhanced by Ramipril, potentially leading to hypoglycemia.
• The combination of Ramipril with other medications that affect the renin-angiotensin-aldosterone system (RAAS), such as aliskiren, can lead to serious complications and should be avoided in certain patient populations.

Following are the food interactions for Ramipril 25MG Tablet:

• Avoid excessive potassium-rich foods like bananas, oranges, and spinach, as Ramipril can increase potassium levels in the body.
• Restrict the use of salt substitutes or low-sodium milk products, as these may contain potassium chloride, which can lead to high potassium levels.
• Limit alcohol consumption as it can lower blood pressure further and increase the risk of dizziness or lightheadedness.
• Grapefruit and grapefruit juice should be avoided, as they can increase the concentration of Ramipril in the blood, leading to potential side effects.
• Maintain a consistent intake of fluids and avoid sudden changes in fluid intake to prevent dehydration or electrolyte imbalances.
• Follow a balanced diet as directed by your doctor, focusing on fruits, vegetables, and whole grains, to support overall health while taking Ramipril.
• Consult your healthcare provider for personalized dietary recommendations based on your medical history and medication regimen.

Ramipril 25MG Tablets should be stored in a cool and dry place, preferably at room temperature (below 25°C). It is crucial to keep the tablets in their original container, tightly sealed, to maintain their integrity and prevent exposure to moisture. Avoid storing them in the bathroom or kitchen cabinets as these areas may have high humidity and temperature fluctuations. Never dispose of the medication by throwing it into the trash or flushing it down the toilet; instead, follow local guidelines for pharmaceutical waste disposal or consult your pharmacist for proper disposal methods. Keep the tablets out of the sight and reach of children and pets to prevent accidental ingestion.

Following are the quick tips for Ramipril 25MG Tablet:

• Consult your doctor before starting this medication and provide your complete medical history.
• Inform your doctor if you are pregnant, breastfeeding, or planning a pregnancy.
• Avoid driving or operating machinery until you know how this medicine affects you as it may cause dizziness.
• Limit alcohol consumption as it may further lower your blood pressure and increase side effects.
• Follow a healthy lifestyle with regular exercise and a balanced diet to enhance the medicine's effectiveness.
• Store the tablets in a cool, dry place, away from direct sunlight and moisture.
• Do not stop taking the medication without consulting your doctor to prevent health complications.