Hifen-X (300mg) 30 Tablets

Dexibuprofen 300mg tablets primarily exert their analgesic, anti-inflammatory, and antipyretic effects through their action as a non-steroidal anti-inflammatory drug (NSAID). The active ingredient, dexibuprofen, is a propionic acid derivative that inhibits the enzyme cyclooxygenase (COX). By blocking COX, dexibuprofen reduces the formation of prostaglandins, which are key mediators of inflammation and pain. This inhibition occurs at the site of inflammation, where dexibuprofen interferes with the arachidonic acid cascade, leading to decreased production of prostaglandin precursors and subsequent reduction in prostaglandin synthesis. As a result, dexibuprofen effectively diminishes pain, inflammation, and fever associated with various conditions, targeting the underlying mechanisms responsible for these symptoms.

Dexibuprofen 300mg

NSAID (Non-steroidal anti-inflammatory drug)

Tablet

The following are the uses of Dexibuprofen 300mg Tablet:

• Used for relieving mild to moderate pain, such as headaches, toothaches, and menstrual cramps.
• Used for reducing inflammation and managing symptoms of rheumatoid arthritis and osteoarthritis.
• Used to lower fever and alleviate discomfort in conditions like flu or post-vaccination reactions.
• Used for treating migraine headaches to reduce pain and associated symptoms.
• Used in managing post-operative pain and inflammation after minor surgical procedures.
• Used for reducing swelling and pain caused by minor injuries or sprains.
• Used for providing temporary relief from discomfort associated with backaches and muscle aches.

In the case of an overdose of Dexibuprofen 300mg Tablets, it is important to recognize the potential symptoms, which may include severe stomach pain, nausea, and vomiting. Other signs of an overdose could be dizziness, ringing in the ears, and blurred vision. If an overdose is suspected, seeking medical advice is essential. Quick action may involve contacting a poison control center or a healthcare professional for guidance on managing the situation effectively.

In the case of a missed dose of Dexibuprofen 300mg Tablet, it is generally recommended to take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one, as this may increase the risk of side effects. If you miss multiple doses, consult your healthcare provider for advice on how to safely resume your medication and adjust your dosing schedule. It is important to adhere to the prescribed dosage and not exceed the recommended amount.

To take Dexibuprofen 300mg Tablets, swallow the tablet whole with a full glass of water, preferably with or after a meal, following the dosage instructions provided by your healthcare professional, typically taken once or twice a day.

Following are the conditions or situations when Dexibuprofen 300mg Tablet should not be used:

• Avoid in patients with a known allergy or hypersensitivity to Dexibuprofen or other non-steroidal anti-inflammatory drugs (NSAIDs).
• Do not use if there is a history of asthma attacks or severe allergic reactions triggered by aspirin or other NSAIDs.
• Contraindicated in individuals with active or recent gastrointestinal bleeding or perforation.
• Not suitable for patients with severe heart failure or severe kidney disease.
• Avoid in patients with a history of heart attack, stroke, or blood clots.
• Should not be used during the last 3 months of pregnancy.
• Do not use in individuals with severe uncontrolled hypertension (high blood pressure).
• Contraindicated in patients with a history of peptic ulcer disease or gastrointestinal bleeding.
• Avoid in cases of severe liver impairment.

The side effects of Dexibuprofen 300mg Tablet may include:

• Stomach pain or upset
• Nausea and vomiting
• Diarrhea
• Dizziness or vertigo
• Headache
• Drowsiness or fatigue
• Skin rash or itching
• Increased blood pressure

Following are the precautions and warnings for Dexibuprofen 300mg Tablet:

• Do not take this medication if you have a known allergy to Dexibuprofen or other NSAIDs (Non-Steroidal Anti-Inflammatory Drugs).
• Individuals with a history of gastrointestinal bleeding or ulcers should use with caution and under medical supervision.
• This medication may increase the risk of cardiovascular events; those with a history of heart disease should exercise caution and consult a doctor.
• Patients with hypertension (high blood pressure) should monitor their blood pressure regularly during treatment.
• Avoid using Dexibuprofen if you have severe liver or kidney impairment without consulting a healthcare professional.
• Do not take this medication during the last trimester of pregnancy as it may cause complications.
• Consult a doctor before using Dexibuprofen if you are trying to conceive, as it may affect fertility.

Following are the drug interactions for Dexibuprofen 300mg Tablet:

• Dexibuprofen may increase the risk of bleeding when combined with anticoagulants (e.g., warfarin, heparin) and antiplatelet drugs (e.g., aspirin, clopidogrel).
• Nonsteroidal anti-inflammatory drugs (NSAIDs) like ibuprofen, naproxen, or diclofenac may compete for the same metabolic pathway, leading to increased levels of Dexibuprofen and potential toxicity.
• When used with diuretics (e.g., furosemide, hydrochlorothiazide), Dexibuprofen can reduce their effectiveness and increase the risk of kidney damage.
• Dexibuprofen can decrease the antihypertensive effect of beta-blockers (e.g., metoprolol, propranolol) and ACE inhibitors (e.g., lisinopril, enalapril).
• Lithium levels may be increased when used with Dexibuprofen, leading to potential lithium toxicity.
• The effectiveness of antihypertensive medications like losartan or amlodipine may be reduced when combined with Dexibuprofen.
• Dexibuprofen may increase the risk of gastrointestinal bleeding when used with corticosteroids (e.g., prednisone, dexamethasone).

Following are the food interactions to be aware of with Dexibuprofen 300mg Tablet:

• Alcohol consumption should be avoided as it can increase the risk of gastrointestinal bleeding and liver toxicity.
• Grapefruit and grapefruit juice should be consumed with caution as they may interfere with the metabolism of Dexibuprofen, potentially increasing its levels in the body and prolonging its effects.
• Fatty foods can delay the absorption of Dexibuprofen, potentially reducing its effectiveness. It is best to take the medication on an empty stomach.
• Avoid caffeine-rich foods and beverages as they can increase the risk of nervousness, insomnia, and increased heart rate when combined with Dexibuprofen.
• Salt substitutes containing potassium should be used with caution as Dexibuprofen may increase potassium levels in the body, potentially leading to hyperkalemia.
• Limit the consumption of spicy foods as they can irritate the stomach and potentially worsen gastrointestinal side effects associated with Dexibuprofen.
• Avoid foods rich in tyramine (aged cheeses, cured meats) as Dexibuprofen may interact with tyramine, leading to increased blood pressure.
• Antacids containing magnesium or aluminum can reduce the absorption of Dexibuprofen if taken together. Maintain a gap of at least 2 hours between their consumption.

Dexibuprofen 300mg Tablets should be stored in a secure and dry location, preferably at room temperature, ensuring protection from direct sunlight and moisture. Keep the medication in its original container, tightly sealed to maintain its integrity. It is crucial to avoid placing the tablets in areas prone to extreme temperatures, such as bathrooms, near stoves, or on radiators, as this can compromise their effectiveness. Regularly check the expiration date, and if the medication is no longer needed or has expired, proper disposal is essential. Avoid flushing or pouring the tablets down the drain; instead, consult a pharmacist or healthcare professional for guidance on safe disposal methods. Always keep medications out of children's reach to prevent accidental consumption.

Following are the quick tips for Dexibuprofen 300mg Tablet:

• Consult your doctor before use, especially if you have a medical history or are taking other medications.
• Take the tablet with or after food to minimize stomach irritation.
• Swallow the tablet whole with a full glass of water, do not crush or chew.
• Avoid alcohol consumption while taking this medication as it may increase the risk of stomach bleeding.
• Do not drive or operate machinery if you experience dizziness or sleepiness after taking the tablet.
• Inform your doctor if you have a history of kidney or liver disease before starting this medication.
• Store the tablets in a cool, dry place, away from direct sunlight and moisture.