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Product Information
Hydroxyurea, the active ingredient in the 500mg capsule, primarily exerts its effects by inhibiting the enzyme ribonucleotide reductase. This enzyme is crucial for the production of deoxyribonucleotides, which are essential building blocks for DNA synthesis. By inhibiting ribonucleotide reductase, hydroxyurea disrupts DNA replication and repair processes in cells. Specifically, it interferes with the S-phase of the cell cycle, leading to cell cycle arrest and reduced proliferation of rapidly dividing cells, such as cancer cells and certain blood cells. This mechanism makes hydroxyurea particularly effective in managing conditions like certain types of leukemia and sickle cell disease, where controlling cell growth and promoting better blood flow are important therapeutic goals.
Antimetabolite/Antineoplastic Agent
Capsule
The following are the uses of Hydroxyurea 500mg Capsule:
In the case of an overdose of Hydroxyurea 500mg Capsules, it is important to recognize the potential severity of the situation. Symptoms may include severe bone marrow suppression, leading to anemia, thrombocytopenia, and leukopenia. Nausea, vomiting, and diarrhea may also occur. In such instances, prompt medical intervention is necessary. Seek emergency medical care and provide healthcare professionals with information about the medication, the amount ingested, and the time of overdose to facilitate appropriate treatment.
In the case of a missed dose of Hydroxyurea 500mg Capsule, it is important to take the medication as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you miss multiple doses, contact your healthcare provider for guidance, as they may advise you to restart the medication or adjust the dosage accordingly. It is recommended to maintain a consistent dosing routine to ensure the effectiveness of the treatment.
To take Hydroxyurea 500mg Capsules, swallow the capsule whole with a full glass of water, as directed by your healthcare provider, usually once or twice daily, and it can be taken with or without food.
Here are the circumstances where Hydroxyurea 500mg Capsule should not be administered:
The side effects of Hydroxyurea 500mg Capsule may include:
Following are the precautions and warnings for Hydroxyurea 500mg Capsule:
Following are the drug interactions for Hydroxyurea 500mg Capsule:
Following are the food interactions for Hydroxyurea 500mg Capsule:
Hydroxyurea 500mg Capsules should be stored in a secure and dry location, preferably in a medicine cabinet, at room temperature (below 25°C/77°F). Keep the capsules in their original container, tightly sealed, to protect them from moisture and light. It is crucial to maintain a consistent storage environment as temperature fluctuations can impact the medication's effectiveness. Ensure the medication is stored away from children and pets to prevent accidental ingestion. When disposing of unused or expired capsules, do not throw them in the trash or flush them down the toilet. Contact your pharmacist or healthcare provider for guidance on proper disposal methods to minimize environmental impact. Regularly check the expiration date on the packaging, and do not use the medication if it is past its expiry.
Following are the quick tips for Hydroxyurea 500mg Capsule:
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