Imazole (200mg) 1 Tablets

Clotrimazole 200mg tablets primarily exert their antifungal activity by disrupting the integrity of fungal cell membranes. The active ingredient, clotrimazole, belongs to the azole class of antifungals. It specifically inhibits the enzyme lanosterol 14-alpha-demethylase, which plays a critical role in the synthesis of ergosterol, a vital component of fungal cell membranes. By blocking this enzyme, clotrimazole impairs the production of ergosterol, leading to defects in the fungal cell membrane structure and function. This disruption in membrane integrity results in the leakage of essential intracellular components, ultimately causing fungal cell death. The mechanism of action selectively targets fungal cells, as it interferes with a process unique to fungal membrane synthesis, making it an effective treatment for various fungal infections.

Clotrimazole 200mg

Antifungal

Tablet

The following are the uses of Clotrimazole 200mg Tablet:

• Used for treating vaginal yeast infections, providing quick relief from itching and discomfort.
• Used to combat fungal infections on the skin, including athlete's foot, jock itch, and ringworm.
• Effective in managing fungal nail infections, promoting healthy nail growth.
• Can be used to alleviate symptoms of oral thrush, restoring oral comfort.
• Suitable for treating diaper rash caused by yeast infections in infants.
• Helps prevent and manage fungal infections in individuals with compromised immune systems.
• Provides relief from itching and irritation associated with fungal skin infections.
• Offers a convenient and direct approach to targeting and eliminating fungal infections.

In the case of an overdose of Clotrimazole 200mg Tablets, it is important to recognize the potential symptoms. These may include nausea, vomiting, and in severe cases, liver damage or even failure. If an overdose is suspected, prompt medical advice should be sought. Treatment for an overdose may involve supportive care and monitoring of liver function, as well as managing any symptoms that arise. It is crucial to act quickly and seek professional guidance to ensure the best possible outcome.

In the case of a missed dose of Clotrimazole 200mg Tablet, it is important to take the medication as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you miss several doses, contact your healthcare provider for guidance, as they may recommend adjusting your dosing schedule or provide specific instructions to ensure the treatment remains effective. It is essential to adhere to the prescribed treatment plan for the best results.

To take Clotrimazole 200mg Tablet, place the tablet in your mouth and swallow it whole with a glass of water, preferably at the same time each day, as directed by your healthcare professional.

Following are the conditions or circumstances when Clotrimazole 200mg Tablet should not be taken:

• Do not use Clotrimazole 200mg Tablet if you have a known allergy or sensitivity to azole antifungals or any of the other ingredients in the medication.
• Avoid using this tablet if you have liver problems or a history of liver disease.
• It is not recommended for individuals with a history of hypersensitivity or severe reactions to similar medications.
• Should not be used if you are breastfeeding, as it may pass into breast milk and harm the nursing infant.
• Do not use this medication if you have a skin condition that is not diagnosed as a fungal infection.
• Clotrimazole tablet is not intended for use in children, and should not be given to them.

The side effects of Clotrimazole 200mg Tablet may include:

• Skin irritation or redness at the application site
• Mild burning or stinging sensation
• Itching or rash
• Dryness or peeling of the skin
• Allergic reactions (such as hives, swelling, or difficulty breathing)
• Headache
• Nausea and vomiting
• Diarrhea

Following are the precautions and warnings for Clotrimazole 200mg Tablet:

• Not suitable for individuals with a known allergy to Clotrimazole or related azole antifungal medications.
• Prolonged use should be avoided without medical supervision as it may lead to fungal or bacterial resistance.
• This medication may cause liver problems, so patients with a history of liver disease should use it with caution and under medical supervision.
• Patients with kidney disease should exercise caution and inform their doctor, as dosage adjustments might be necessary.
• Elderly individuals may be more susceptible to side effects, and regular monitoring is advised.
• Not recommended for use during pregnancy, especially in the first trimester, unless clearly needed and under medical supervision.
• Breastfeeding women should consult their doctor, as Clotrimazole may pass into breast milk and potentially cause harm to the nursing infant.

Following are the drug interactions for Clotrimazole 200mg Tablet:

• When taken with oral hypoglycemic agents, it may increase the risk of hypoglycemia.
• Concomitant use with oral anticoagulants like warfarin can potentiate the anticoagulant effect, requiring close monitoring of prothrombin time.
• It may inhibit the metabolism of HMG-CoA reductase inhibitors (statins), increasing the risk of myopathy and rhabdomyolysis.
• Cytochrome P450 inhibitors like ritonavir and ketoconazole can increase the plasma concentration of Clotrimazole.
• CYP3A4 inducers such as rifampicin, carbamazepine, and phenytoin may decrease Clotrimazole levels.
• Alcohol consumption can increase the risk of liver toxicity when using Clotrimazole.
• The effectiveness of oral contraceptives may be reduced, so alternative contraceptive methods are recommended.

Following are the food interactions for Clotrimazole 200mg Tablet:

• Avoid excessive alcohol consumption while taking this medication as it may increase the risk of liver problems and affect the metabolism of the drug.
• Grapefruit and grapefruit juice should be consumed with caution as they can inhibit CYP3A4 enzyme, potentially leading to increased Clotrimazole levels in the body.
• Avoid high-fat meals as they may decrease the absorption of Clotrimazole, reducing its effectiveness.
• Caffeine intake should be monitored as Clotrimazole can inhibit its metabolism, potentially increasing caffeine-related side effects.
• Limit the consumption of foods rich in vitamin A, such as liver, as Clotrimazole may increase vitamin A levels in the body, leading to potential toxicity.
• Be cautious with spicy foods as Clotrimazole may cause gastrointestinal irritation, and spicy foods can exacerbate this effect.
• Avoid dairy products like milk and yogurt, as they can bind with Clotrimazole, reducing its absorption and effectiveness.

Clotrimazole 200mg Tablets should be stored in a cool and dry place, preferably at room temperature, away from direct exposure to sunlight, heat, and moisture. The tablets should be kept in their original packaging, ensuring the container is tightly sealed to maintain their integrity. It is crucial to store medications out of the reach of children and pets to prevent accidental ingestion. When disposing of unused or expired tablets, do not throw them in the trash or flush them down the toilet. Instead, consult your pharmacist or healthcare provider for appropriate disposal methods to minimize environmental impact and ensure safety. Regularly check the expiration date on the packaging, and do not use the medication if it has passed its expiry.

Following are the quick tips for Clotrimazole 200mg Tablet:

• Consult your doctor before starting this medication to ensure it's suitable for your condition.
• Take the tablet orally, as directed by your healthcare professional.
• Swallow the tablet whole with a full glass of water; do not crush or chew it.
• Maintain a consistent dosing schedule; take it at the same time each day.
• Complete the full course of treatment, even if symptoms improve, to ensure the infection is fully treated.
• Store the medication at room temperature, away from moisture and sunlight.
• Inform your doctor about any other medications you are taking to avoid potential interactions.