Imol Plus 30s TAb

Paracetamol, Caffeine, and Ibuprofen tablet have distinct mechanisms of action. Paracetamol primarily acts by inhibiting the synthesis of prostaglandins in the central nervous system, reducing pain signaling and decreasing body temperature. Caffeine, a central nervous system stimulant, enhances the analgesic effect of paracetamol by blocking adenosine receptors, leading to increased alertness and reduced perception of pain. Ibuprofen, a non-steroidal anti-inflammatory drug (NSAID), exerts its action by inhibiting cyclooxygenase (COX) enzymes, particularly COX-1 and COX-2, which are involved in the production of prostaglandins. This inhibition reduces inflammation, pain, and fever by decreasing the production of inflammatory mediators.

Analgesic, Stimulant, NSAID.

Tablet

The following are the uses of Paracetamol, Caffeine, ibuprofen Tablet:

• Used for relieving mild to moderate pain such as headaches, toothaches, and menstrual cramps.
• Used to reduce fever and ease discomfort associated with colds and flu.
• Used for temporary relief of minor aches and pains from muscle strains or sprains.
• Helps to alleviate symptoms of tension headaches and migraines.
• Can be used to reduce inflammation and ease pain in conditions like arthritis.
• Provides alertness and boosts energy levels, especially when combined with paracetamol.
• Effective in reducing discomfort and inflammation from minor injuries.
• Offers short-term relief from various aches and pains, providing comfort and support during recovery.

In the case of an overdose of Paracetamol, Caffeine, and ibuprofen tablets, individuals may experience symptoms such as nausea, vomiting, abdominal pain, and in severe cases, liver damage or kidney injury. Caffeine overdose can lead to restlessness, rapid heartbeat, and insomnia. Ibuprofen overdose can cause gastrointestinal bleeding and kidney problems. Prompt medical intervention is necessary, as early treatment can help prevent potential organ damage and reduce the severity of symptoms.

In the case of a missed dose of Paracetamol, it is generally recommended to take the missed dose as soon as you remember, but if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. For Caffeine, if you miss a dose, you may take it as soon as you remember, but avoid taking it near your bedtime as it may interfere with sleep. With Ibuprofen, if a dose is missed, take it as soon as you remember, but if it's close to the time for your next dose, skip the missed dose and resume your regular dosing schedule. It is important to follow the prescribed dosage and consult a healthcare professional if you have any concerns.

To take the Paracetamol, Caffeine, and Ibuprofen tablet, swallow the tablet whole with a full glass of water, preferably with or after a meal, following the dosage instructions provided by your healthcare professional, which may include the frequency and duration of use based on your specific medical condition and response to treatment.

Following are the conditions/situations when Paracetamol, Caffeine, Ibuprofen Tablet should not be used:

• Not recommended for individuals with a known allergy to any of the ingredients, including paracetamol, caffeine, or ibuprofen.
• Contraindicated in patients with a history of gastrointestinal bleeding or perforation.
• Should not be used in individuals with severe heart-related conditions or a history of heart attack.
• Not suitable for people with severe liver or kidney impairment.
• Avoid using this medication if you have a history of asthma or other respiratory conditions triggered by ibuprofen or other NSAIDs.
• Contraindicated in patients with bleeding disorders or those taking anticoagulant medications.
• Should not be used during the last trimester of pregnancy.
• Not recommended for individuals with a history of peptic ulcers or gastrointestinal disorders.

The side effects of Paracetamol, Caffeine, Ibuprofen Tablet may include:

• Nausea and vomiting
• Stomach pain or discomfort
• Diarrhea
• Headache or dizziness
• Increased heart rate or palpitations (due to caffeine)
• Insomnia or restlessness
• Skin rash or itching
• Gastrointestinal bleeding (in rare cases)

Following are the precautions and warnings for Paracetamol, Caffeine, and Ibuprofen Tablet:

• Avoid in patients with known hypersensitivity or allergy to any of the components, including other NSAIDs or acetaminophen.
• This medication should be used with caution in patients with a history of gastrointestinal problems, as it may cause irritation or bleeding.
• Patients with liver or kidney impairment should be closely monitored, as these conditions may affect the metabolism and elimination of the drug.
• Caffeine may increase the effects of ibuprofen, so monitor for increased side effects.
• Do not exceed the recommended dosage, as it may lead to severe liver damage or other adverse effects.
• Avoid alcohol consumption while taking this medication, as it may enhance the risk of gastrointestinal bleeding and liver toxicity.
• This medication is not recommended for long-term use, and should only be used for short-term relief of pain and fever.

Following are the drug interactions for Paracetamol, Caffeine, and Ibuprofen Tablet:

• Paracetamol may prolong the effects of anticoagulants like warfarin, requiring close monitoring of INR (International Normalized Ratio).
• Ibuprofen can increase the risk of bleeding when taken with other non-steroidal anti-inflammatory drugs (NSAIDs) or antiplatelet medications.
• Caffeine may reduce the sedative effects of certain medications, such as benzodiazepines and opioids.
• Antacids containing aluminum or magnesium may decrease the absorption of ibuprofen and paracetamol.
• Ibuprofen may reduce the effectiveness of antihypertensive drugs, including ACE inhibitors and diuretics.
• Paracetamol can increase the risk of hepatotoxicity when taken with other potentially hepatotoxic drugs.
• Probenecid, a uricosuric medication, may increase the plasma concentrations of paracetamol and ibuprofen.

Following are the food interactions for Paracetamol, Caffeine, and Ibuprofen Tablet:

• Grapefruit and grapefruit juice consumption should be limited as they can inhibit the metabolism of Caffeine, leading to increased caffeine levels and potential side effects like jitteriness and insomnia.
• Alcohol intake should be avoided as it can increase the risk of liver damage when combined with Paracetamol, and may also enhance the stomach irritation effects of Ibuprofen.
• Caffeinated beverages like coffee and tea can interact with Caffeine, potentially causing excessive caffeine-related side effects.
• Fatty foods can delay the absorption of Ibuprofen, potentially reducing its effectiveness.
• Spicy foods should be consumed in moderation as they may exacerbate the stomach-related side effects of Ibuprofen.
• Avoid high-protein meals when taking Paracetamol, as they can reduce its absorption rate.
• Antioxidant-rich foods like berries and green leafy vegetables may enhance the anti-inflammatory effects of Ibuprofen.
• Dairy products might slightly reduce the absorption of Ibuprofen, but this effect is generally not significant.

Paracetamol, Caffeine, and Ibuprofen Tablets should be stored in a cool, dry place, preferably at room temperature, away from direct exposure to sunlight, heat, and moisture. The original packaging should be tightly sealed to maintain its integrity and protect it from environmental factors. It is crucial to adhere to the expiration date on the package, and if the tablets are no longer needed or have expired, they should be disposed of safely. Proper disposal methods should be followed, avoiding flushing or pouring them down the drain. Consult your pharmacist or local waste management guidelines for appropriate disposal instructions. Keep these medications out of children's reach to prevent accidental consumption.

Following are the quick tips for Paracetamol, Caffeine, and Ibuprofen Tablets:

• Consult a doctor before use, especially if you have underlying health conditions.
• Swallow the tablet whole with water, do not crush or chew.
• Take as directed, do not exceed the recommended dosage.
• Avoid caffeine-containing beverages while taking these tablets.
• Store in a cool, dry place, away from direct sunlight.
• Inform your doctor if you are pregnant or breastfeeding.
• Do not take with other painkillers without medical advice.
• Always read the patient information leaflet before use.