INACEF 500MG CAP

Cefuroxime capsules work by interfering with the synthesis of the bacterial cell wall, leading to its weakening and eventual rupture. The active ingredient, cefuroxime, is a second-generation cephalosporin antibiotic that specifically targets the final stage of peptidoglycan synthesis in bacterial cell walls. It achieves this by binding to and inhibiting the activity of penicillin-binding proteins (PBPs), which are essential enzymes responsible for cross-linking the peptidoglycan chains. By disrupting this crucial step in cell wall formation, cefuroxime prevents the bacteria from maintaining their structural integrity, ultimately leading to cell lysis and bacterial death.

Cefuroxime

Cephalosporin antibiotic.

Capsule

The following are the uses of Cefuroxime Capsule:

• Used for treating bacterial infections such as pneumonia, bronchitis, and tonsillitis.
• Used for managing skin and soft tissue infections like cellulitis and impetigo.
• Used for treating urinary tract infections, including bladder and kidney infections.
• Used for addressing bone and joint infections, particularly in children.
• Used for the prevention of infections during surgical procedures.
• Used for managing certain types of stomach and intestinal infections.
• Used for treating bacterial meningitis, an infection of the brain and spinal cord membranes.

In the case of an overdose of Cefuroxime capsules, individuals may experience symptoms such as nausea, vomiting, diarrhea, and abdominal pain. These symptoms can be more severe and may include kidney issues, seizures, and in extreme cases, a life-threatening allergic reaction. Prompt medical intervention is necessary, and individuals should seek emergency care if they suspect an overdose. Medical professionals will provide the necessary treatment to manage the overdose and its associated symptoms effectively.

In the case of a missed dose of Cefuroxime Capsule, it is important to take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one. If you miss multiple doses, contact your healthcare provider for guidance on how to proceed, as they may recommend adjusting your dosage or provide specific instructions for catching up on missed doses safely.

To take Cefuroxime Capsule, swallow the capsule whole with a full glass of water, ensuring you do not break, crush, or chew the capsule, and follow the prescribed dosage instructions provided by your healthcare professional for the duration of the treatment period.

Following are the conditions when Cefuroxime Capsule should not be used:

• Avoid using if you have a known allergy to Cefuroxime or any other cephalosporin antibiotics.
• Do not take if you have a history of severe allergic reactions to penicillin.
• Contraindicated in patients with a history of severe gastrointestinal problems, especially colitis.
• Not recommended for individuals with kidney disease or impaired kidney function.
• Should not be used if you have a history of seizures or conditions that increase the risk of seizures.
• Avoid using Cefuroxime if you have a history of severe or life-threatening allergic reactions to any medication.
• Not suitable for patients with a history of severe diarrhea caused by antibiotics.

The side effects of Cefuroxime Capsule may include:

• Diarrhea
• Nausea and vomiting
• Abdominal pain
• Skin rash or itching
• Headache
• Dizziness
• Vaginal itching or discharge
• Joint pain

Following are the precautions and warnings for Cefuroxime Capsule:

• Do not take Cefuroxime if you have a known allergy to cephalosporin antibiotics or any other allergies; inform your doctor about any previous allergic reactions.
• Patients with kidney disease or liver impairment should use this medication with caution, as dosage adjustments may be necessary.
• Cefuroxime may cause diarrhea; if it becomes severe or persistent, contact your doctor as it could be a sign of a more serious condition.
• This medication may reduce the effectiveness of certain contraceptive methods, so alternative birth control methods are recommended.
• Elderly patients may be more susceptible to side effects; regular monitoring is advised.
• Cefuroxime should be used with caution in patients with a history of gastrointestinal diseases as it may exacerbate these conditions.
• Always complete the full course of treatment as prescribed by your healthcare provider to ensure the infection is properly treated.

Following are the drug interactions for Cefuroxime Capsule:

• Probenecid can decrease the renal tubular secretion of cefuroxime, potentially leading to increased plasma concentrations.
• High doses of Cefuroxime may reduce the effectiveness of combined oral contraceptives, increasing the risk of unintended pregnancy.
• Concurrent use of Cefuroxime with nephrotoxic drugs (e.g., aminoglycosides, loop diuretics) may increase the risk of kidney damage.
• Cefuroxime can decrease the absorption of iron supplements when taken together, reducing the effectiveness of iron therapy.
• Alcohol may increase the risk of gastrointestinal side effects when used with Cefuroxime.
• Cefuroxime may decrease the efficacy of live typhoid vaccine and live cholera vaccine.
• Antacids containing magnesium or aluminum may reduce the absorption of Cefuroxime when taken simultaneously.

Following are the food interactions for Cefuroxime Capsule:

• Avoid consuming large amounts of dairy products, calcium supplements, or antacids containing calcium as they may reduce the absorption of Cefuroxime.
• Grapefruit and grapefruit juice should be consumed with caution as they can affect the liver enzymes responsible for metabolizing Cefuroxime, leading to higher drug levels in the body.
• Alcohol intake is generally not recommended during treatment with Cefuroxime as it may increase the risk of gastrointestinal side effects and potential liver toxicity.
• Avoid high-fat meals as they may delay the absorption of Cefuroxime, potentially affecting its effectiveness.
• Probiotics and fermented foods may help restore healthy gut bacteria that may be disrupted by Cefuroxime, but consult your doctor for specific recommendations.
• Vitamin K-rich foods like leafy greens may be beneficial as Cefuroxime can interfere with vitamin K absorption, affecting blood clotting.
• Avoid excessive salt and sugar intake to maintain a balanced diet and support overall health during the medication period.
• Stay hydrated by drinking plenty of water to support kidney function and aid in the elimination of Cefuroxime from the body.

Cefuroxime capsules should be stored in a cool and dry place, preferably at room temperature (around 20-25°C), ensuring protection from light and moisture. It is crucial to keep the medication in its original container, tightly sealed, to maintain its integrity and prevent contamination. Do not store cefuroxime in the bathroom or kitchen, as these areas are prone to temperature fluctuations and moisture. Always check the expiration date, and if the medication is expired or no longer needed, dispose of it carefully. Proper disposal methods are essential, so consult a pharmacist or healthcare professional for guidance on how to safely discard cefuroxime capsules without causing harm to the environment. Keep the medication out of children's reach to prevent accidental consumption.

Following are the quick tips for Cefuroxime Capsule:

• Swallow the capsule whole with a full glass of water; do not crush, chew, or break it.
• Take the capsule as directed by your doctor, typically every 12 hours or as prescribed.
• Ensure you complete the full prescribed course, even if you feel better before finishing all capsules.
• Avoid taking antacids or iron supplements within 2 hours of taking the medicine.
• Store the capsules at room temperature, away from moisture and light.
• Inform your doctor if you have kidney disease, as the dose may need adjustment.
• Contact a healthcare professional if you experience severe diarrhea during or after treatment.