Inocef (250mg) 1 Vial Injection (IM)

Ceftriaxone 250mg injection is an antibiotic medication used to treat a wide range of bacterial infections. It belongs to the class of cephalosporin antibiotics and works by inhibiting the growth of bacteria, making it effective against various infections caused by susceptible organisms. This medication is commonly used to treat infections such as respiratory tract infections, urinary tract infections, skin and soft tissue infections, and gonorrhea. It is also used in the treatment of more severe infections like bacterial meningitis, sepsis, and bone or joint infections. Ceftriaxone is typically administered via injection, either intramuscularly or intravenously, and should be given under the supervision of a healthcare provider. It is important to follow the prescribed dosage and complete the full course of treatment to ensure the infection is fully resolved and to prevent antibiotic resistance.

Ceftriaxone 250mg

third-generation cephalosporin

injection

Following are the uses of Ceftriaxone 250mg Injection:

• Treats respiratory tract infections, including pneumonia and bronchitis
• Addresses urinary tract infections caused by susceptible bacteria
• Effective against skin and soft tissue infections such as cellulitis and abscesses
• Used in the treatment of gonorrhea, a sexually transmitted infection
• Helps manage bacterial meningitis by targeting the causative pathogens
• Treats septicemia (bloodstream infections) caused by susceptible bacteria
• Administered for bone and joint infections, including osteomyelitis
• Treats abdominal infections like peritonitis and intra-abdominal abscesses
• Used for prophylaxis in surgical procedures to prevent infections
• Helps manage infections in individuals with weakened immune systems

Dosage of Ceftriaxone 250mg Injection:

• For respiratory tract infections

• For urinary tract infections

• For skin and soft tissue infections

• For gonorrhea

• For bacterial meningitis

• For septicemia

• For bone and joint infections

• For abdominal infections

• For surgical infection prophylaxis

In case of an overdose of Ceftriaxone 250mg Injection, it is important to seek immediate medical attention. Symptoms of an overdose may include nausea, vomiting, diarrhea, and changes in liver or kidney function. Overdose can also lead to severe allergic reactions, such as swelling, difficulty breathing, or skin rashes. If an overdose is suspected, contact a healthcare provider or poison control center immediately. Treatment for an overdose typically involves supportive care, such as hydration and monitoring of vital signs. In some cases, adjustments to the dosage or discontinuation of the medication may be necessary. It is crucial to follow the prescribed dosage regimen and not exceed the recommended dose to prevent potential complications.

In case of a missed dose of Ceftriaxone 250mg Injection, contact your healthcare provider for guidance. Since this medication is typically administered in a clinical setting by a healthcare professional, missed doses are rare. If you were scheduled for an injection and missed it, your healthcare provider will determine the best course of action, which may involve rescheduling the injection or adjusting the treatment plan. Never attempt to administer the injection yourself. Always follow your healthcare provider's instructions and complete the full course of treatment to ensure the infection is fully treated.

Ceftriaxone 250mg Injection should be administered by a healthcare professional, either intramuscularly or intravenously, depending on the severity and location of the infection being treated. It is important to follow the prescribed dosage and administration schedule as directed by your healthcare provider. The injection is typically given in a medical setting, such as a hospital or clinic, under sterile conditions to reduce the risk of infection. If you are receiving the injection as part of an outpatient treatment plan, ensure you attend all scheduled appointments to receive the proper dosage. Always consult your healthcare provider if you have any concerns or questions regarding the administration of the medication.

When not to use Ceftriaxone 250mg Injection:

• If allergic to ceftriaxone, cephalosporins, or any of its components.
• In patients with a history of severe hypersensitivity reactions to penicillin or other beta-lactam antibiotics.
• In newborns with hyperbilirubinemia (jaundice) or those requiring calcium-containing intravenous solutions, as it may cause precipitates in the lungs and kidneys.
• In patients with severe liver or kidney impairment, unless dose adjustments and close monitoring are carried out by a healthcare provider.
• If you are taking calcium-containing intravenous solutions concurrently, due to the risk of fatal precipitate formation.
• For treating infections caused by organisms resistant to ceftriaxone.
• In premature infants or neonates under 41 weeks postmenstrual age (gestational + chronological age).

Side effects of Ceftriaxone 250mg Injection include:

• Rash
• Diarrhea
• Nausea
• Vomiting
• Fever
• Headache
• Dizziness
• Pain
• Inflammation
• Allergies
• Anemia
• Thrombocytopenia
• Nephrotoxicity
• Hepatotoxicity

Precautions and Warnings for Ceftriaxone 250mg Injection include:

• Use with caution if you have a history of allergic reactions to ceftriaxone, cephalosporins, or any other ingredients in the injection.
• Use cautiously in individuals with a history of gastrointestinal disorders, such as colitis or gastrointestinal bleeding.
• Consult a doctor before use during pregnancy or breastfeeding to assess potential risks and benefits.
• Inform your doctor of any medications you are taking, especially those that may interact with ceftriaxone (e.g., warfarin, aminoglycosides, or calcium-containing intravenous solutions).
• Do not use in newborns with hyperbilirubinemia, as it may cause severe complications.
• Long-term use of ceftriaxone may increase the risk of gallbladder issues, so monitor for signs of gallstones or biliary sludge.
• Avoid sudden discontinuation without consulting a doctor, as it may lead to worsened infection.
• Store properly, keep out of reach of children, and prevent accidental injection.

Drug interactions of Ceftriaxone 250mg Injection include:

• May interact with warfarin, as ceftriaxone can increase the risk of bleeding by affecting blood clotting factors.
• Can interact with aminoglycoside antibiotics (e.g., gentamicin), increasing the risk of nephrotoxicity and ototoxicity.
• Use with caution when combined with diuretics like furosemide, as it may increase the risk of renal dysfunction.
• Can interact with calcium-containing intravenous solutions, potentially leading to precipitation in the lungs and kidneys, especially in neonates.
• May increase the effects of oral anticoagulants, such as warfarin, requiring close monitoring of coagulation parameters.
• Ceftriaxone may affect the pharmacokinetics of other drugs metabolized by the liver, so dose adjustments might be needed.
• Ceftriaxone may reduce the effectiveness of certain vaccines, such as the typhoid vaccine, when taken together.

Food interactions of Ceftriaxone 250mg Injection include:

• Ceftriaxone does not have direct food interactions, but it may affect the absorption of certain nutrients or interact with foods when given in combination with specific medications.
• It may reduce the absorption of fat-soluble vitamins like vitamin K, which could potentially affect blood clotting, particularly in patients with prolonged use.
• Taking ceftriaxone with high-fat meals may potentially impact the absorption or efficacy of the medication in some patients, though the effect is generally minimal.
• It is advisable to avoid consuming alcohol during treatment with ceftriaxone, as it could increase the risk of adverse reactions such as nausea, vomiting, and gastrointestinal discomfort.

Ceftriaxone 250mg Injection should be stored in a cool, dry place, away from direct light and moisture. It should be kept at a temperature between 2°C and 8°C (36°F and 46°F), typically in a refrigerator. Do not freeze the injection. Ensure that the medication is stored in its original packaging to protect it from contamination and accidental exposure. Keep the injection out of the reach of children to prevent accidental ingestion or misuse. If the vial has been opened or the medication has expired, it should be disposed of properly, following local disposal guidelines or as advised by a healthcare provider. Never dispose of medication in household trash or sewage unless instructed to do so. Always consult a healthcare provider for appropriate disposal recommendations.

Quick Tips for using Ceftriaxone 250mg Injection:

• Always use ceftriaxone as prescribed by your healthcare provider and ensure it is administered by a healthcare professional.
• Inform your doctor of any allergies, especially to cephalosporins, penicillins, or other antibiotics, before using ceftriaxone.
• If using ceftriaxone for a prolonged period, monitor liver and kidney function as advised by your healthcare provider.
• Avoid alcohol during treatment, as it may increase the risk of side effects like nausea and vomiting.
• Make sure to complete the full course of treatment, even if you feel better, to avoid the development of antibiotic resistance.
• Keep the injection in a cool, dry place and ensure it is not exposed to excessive heat or moisture.
• Do not administer the injection yourself unless trained by a healthcare provider.
• If you miss a dose, contact your healthcare provider for guidance on how to proceed.
• Regularly monitor for signs of allergic reactions, such as rash or difficulty breathing, and report them to your healthcare provider.