INOFOLIC COMBI CAP (30S)

INOFOLIC COMBI CAP (30S)

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  • Manufacturer GALAXY PHARMACEUTICALS (PVT.) LTD.
  • Generic Name

    Folic Acid

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Product Information

  • Description
  • Ingredients
  • Drug Class
  • Dosage Form
  • Uses
  • Dosage
  • In case of Overdose
  • Missed Dose
  • How To Use
  • When Not to Use
  • Side Effects
  • Precautions & Warnings
  • Drug Interactions
  • Food Interactions
  • Storage/Disposal
  • Control Drug
  • Quick Tips, if any
  • Description

    Folic acid, also known as vitamin B9, primarily acts as a cofactor in various enzymatic reactions involved in the synthesis of DNA, RNA, and certain amino acids. Its mechanism of action revolves around its role in one-carbon metabolism, where it is converted to its active forms, such as tetrahydrofolate (THF) and its derivatives. These active forms participate in the transfer of one-carbon units, such as methyl, formyl, and methylene groups, which are essential for the synthesis of nucleic acids. THF facilitates the conversion of homocysteine to methionine, which is required for the synthesis of S-adenosylmethionine (SAM), a universal methyl donor involved in numerous biochemical reactions. By providing these one-carbon units, folic acid supports DNA replication, cell division, and the maintenance of healthy cells, particularly during periods of rapid cell growth and development, such as in pregnancy and fetal development.

  • Ingredients

    Folic Acid

  • Drug Class

    Vitamin B9 supplement

  • Dosage Form

    Capsule

  • Uses

    The following are the uses of Folic Acid Capsule:

    • Used for preventing and treating low blood levels of folic acid.
    • Used to support healthy fetal development during pregnancy, reducing the risk of neural tube defects.
    • Used to enhance the effectiveness of certain medications, such as methotrexate.
    • Used to manage certain types of anemia caused by folic acid deficiency.
    • Used for improving overall health and well-being, particularly in individuals with poor diets.
    • Used to support cardiovascular health and reduce the risk of heart-related issues.
    • Used in the treatment of certain types of depression, as it can enhance the effectiveness of antidepressant medications.
    • Used to promote healthy cell growth and function, particularly in tissues with rapid cell turnover.
  • Dosage

    This capsule is usually recommended to be taken once a day. Follow your doctor's prescription and directions to use any supplement.

  • In case of Overdose

    In the case of an overdose of Folic Acid Capsules, it is important to remain calm and seek medical advice promptly. While folic acid is generally considered safe, excessive intake may lead to symptoms such as nausea, abdominal discomfort, and diarrhea. If you suspect an overdose, contact a healthcare professional or poison control center for guidance. They will provide specific instructions based on the amount ingested and individual factors, ensuring appropriate care and treatment.

  • Missed Dose

    In the case of a missed dose of Folic Acid Capsule, it is generally recommended to take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, it is best to skip the missed dose and continue with your regular dosing schedule. Avoid taking a double dose to make up for a missed one, as this may increase the risk of side effects. If you frequently miss doses, consider setting reminders or asking someone to help you remember to take your medication as prescribed. Consult your healthcare provider if you have any concerns or questions regarding missed doses.

  • How To Use

    To take the Folic Acid Capsule, simply swallow the capsule whole with a glass of water, preferably at the same time each day, following the dosage instructions provided by your healthcare professional.

  • When Not to Use

    Following are the conditions/situations when Folic Acid Capsule should not be used:

    • Should not be used in individuals with a known allergy to folic acid or any of the excipients in the capsule formulation.
    • Not suitable for individuals with pernicious anemia, as folic acid does not treat the underlying vitamin B12 deficiency.
    • Contraindicated in patients with untreated or undiagnosed anemia, as it may mask the symptoms and delay proper diagnosis.
    • Should not be used as a sole treatment for anemia without investigating the underlying cause.
    • Not recommended for individuals with a history of seizures, as high doses of folic acid may lower the seizure threshold.
    • Contraindicated in patients with a rare genetic condition called untreated folic acid metabolism disorders, such as methylenetetrahydrofolate reductase (MTHFR) deficiency.
    • Should not be used to prevent or treat heart disease without consulting a healthcare professional, as high doses may be required and should be monitored.
  • Side Effects

    The side effects of Folic Acid Capsule may include:

    • Nausea and upset stomach.
    • Diarrhea.
    • Skin reactions such as rashes, itching, or redness.
    • Loss of appetite.
    • Sleep disturbances, including insomnia.
    • A feeling of nervousness or irritability.
    • Changes in taste, including a metallic taste in the mouth.
    • Allergic reactions, including swelling of the face, lips, or tongue.
  • Precautions & Warnings

    Following are the precautions and warnings for Folic Acid Capsule:

    • Do not exceed the recommended dosage, as high doses of folic acid may mask a vitamin B12 deficiency, which is a serious condition.
    • If you have a history of allergies or are currently taking any medications, inform your healthcare provider before starting Folic Acid.
    • Patients with pernicious anemia, a condition caused by vitamin B12 deficiency, should not solely rely on Folic Acid and must seek proper medical treatment.
    • Folic Acid may cause allergic reactions in some individuals; seek medical attention if you experience any symptoms such as rash, itching, or difficulty breathing.
    • This medication may cause gastrointestinal side effects; if you have a history of digestive issues, monitor your symptoms closely.
    • If you have a history of seizures or epilepsy, use Folic Acid with caution as it may influence seizure control.
    • Always store Folic Acid capsules in a cool, dry place, away from direct sunlight and moisture, to maintain their potency.
  • Drug Interactions

    Following are the drug interactions for Folic Acid Capsule:

    • Phenytoin, phenobarbital, primidone, and methotrexate may reduce the effectiveness of folic acid.
    • Folic acid may interfere with the absorption of the anti-seizure medication, phenytoin.
    • Sulfasalazine and triamterene can decrease folate levels, requiring higher doses of folic acid.
    • Methotrexate, when used for cancer treatment, may be less effective with high doses of folic acid.
    • Folic acid supplementation might decrease the effectiveness of pyrimethamine in treating toxoplasmosis.
    • Antacids containing calcium carbonate may reduce folic acid absorption.
    • Folic acid may increase the toxicity of 5-fluorouracil, a chemotherapy drug.
  • Food Interactions

    Following are the food interactions for Folic Acid Capsule:

    • Folic acid absorption can be hindered by coffee, tea, or carbonated beverages, so avoid consuming these around the time you take the capsule.
    • Alcohol should be limited or avoided as it can interfere with folic acid metabolism and reduce its effectiveness.
    • Consuming foods rich in folate, such as leafy green vegetables, beans, and citrus fruits, can complement the effects of the capsule and ensure adequate folate levels.
    • Folic acid absorption can be enhanced by consuming it with food, especially foods containing healthy fats, which aid in its uptake.
    • Avoid excessive intake of vitamin C supplements, as very high doses may interfere with folic acid's function in the body.
    • Certain medications, like antacids, can affect folic acid absorption, so consult your healthcare provider about potential interactions.
    • Avoid consuming raw eggs, as a protein in raw eggs called avidin can bind to folic acid and reduce its absorption.
    • A balanced diet is essential to ensure the effectiveness of the capsule, as a healthy gut environment supports optimal folic acid utilization.
  • Storage/Disposal

    Storage and disposal of Folic Acid Capsules should be done with care. Store the capsules in a cool, dry place, preferably at room temperature, away from sunlight and moisture. Keep the bottle tightly sealed to maintain its integrity. Do not expose the capsules to extreme temperatures or store them in the bathroom, as heat and humidity can degrade the medication. Always check the expiration date, and if the capsules are past their prime, do not use them and dispose of them properly. For disposal, do not flush the capsules down the toilet; instead, consult your pharmacist for guidance on safe disposal methods. Keep all medications out of children's reach to prevent accidental consumption.

  • Control Drug

    No

  • Quick Tips, if any

    Following are the quick tips for Folic Acid Capsule:

    • Swallow the capsule whole with a glass of water, do not chew or crush it.
    • Take as directed by your doctor or healthcare provider.
    • Folic acid is best absorbed on an empty stomach, consider taking it 30 minutes before meals.
    • Maintain a consistent daily dose timing for better results.
    • Do not take double doses to make up for a missed one.
    • Inform your doctor if you are pregnant or breastfeeding before taking this medication.
    • Store in a cool, dry place, away from direct sunlight and moisture.

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