Insuget R (100IU/ml) 10ml Injection

Insuget R (100IU/ml) 10ml Injection

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  • Manufacturer Getz Pharma (Pvt.) Ltd.
  • Generic Name Regular human insulin

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Product Information

  • Description
  • Ingredients
  • Drug Class
  • Dosage Form
  • Uses
  • Dosage
  • In case of Overdose
  • Missed Dose
  • How To Use
  • When Not to Use
  • Side Effects
  • Precautions & Warnings
  • Drug Interactions
  • Storage/Disposal
  • Description

    The hormone insulin is produced in the pancreas, and its primary function is to regulate blood sugar levels in the body. When we consume food, it is broken down into glucose molecules, which are absorbed into the bloodstream and used by the body as an energy source. In people with diabetes, however, the body either doesn't produce enough insulin or can't use it as effectively as it should. This leads to a condition known as insulin resistance, where glucose remains in the bloodstream instead of reaching the body's cells, resulting in high blood sugar levels. To address this, Human Insulin, a laboratory-made insulin (recombinant DNA origin), is used to improve blood sugar levels in people with diabetes mellitus. This insulin is engineered to be identical to the insulin produced by the human pancreas. When introduced into the body, Human Insulin binds to receptors on cells, marking them for absorption and facilitating the use of glucose from the blood. By introducing Human Insulin, it mimics the action of naturally produced insulin and promotes the uptake of glucose into cells, thereby lowering blood sugar levels and preventing complications arising from high blood sugar.

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  • Ingredients

    Regular human insulin
  • Drug Class

    Insulin

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  • Dosage Form

    injection

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  • Uses

    Unveiling its multifaceted uses and transformative applications as follows:

    • Treats insulin deficiency or forms of diabetes mellitus that are unresponsive to dietary management.
    • Certifications are granted originally in Canada and shipped to other countries.
    • Used for the management of type 2 diabetes and type 1 diabetes mellitus.
    • Responsible for regulating blood glucose levels in the body and is very important for metabolism.
    • Prescription only drug composed of biosynthetic human insulin, synthesized in a laboratory.
    • Helps people with diabetes lead a normal and healthy life when used properly by preventing complications stemming from the disease.

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  • Dosage

    Tailoring Treatment for Optimal Health, Prescribed Medication Dosage is:

    • Human Insulin rDNA 100IU/ml is used to treat adults and children with type 1 diabetes and adults with type 2 diabetes.
    • The usual starting dose is usually 0.2 to 0.4 units per kg of body weight, injected subcutaneously, per day, or 100 to 200 units per day for a person weighing 70 kg (154 pounds).
    • Dosage is individualized based on glucose monitoring results, and can be adjusted upward or downward depending on blood glucose levels.
    • Hypoglycemia may occur in case of overdose, and glucagon injection may be required if the patient cannot take in any source of sugar.
    • Hypoglycemia can also occur due to too frequent injections or incorrect dosage, particularly in young children, renal failure, or elderly patients.

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  • In case of Overdose

    An overdose of human insulin RDNA 100IU/ml can lead to hypoglycemia and requires immediate medical attention. If a patient is suspected of experiencing this, they should be monitored closely for symptoms such as sweating, tremors, confusion, dizziness, or unconsciousness. Should any symptoms arise, it is essential to treat them immediately with oral glucose, or if they're unable to swallow, intravenous glucose is an option. Subcutaneous insulin administration should be temporarily halted, and other hypoglycemia treatments may be prescribed by a medical professional. The patient's family and friends should be educated on the signs of hypoglycemia and warned to seek immediate medical attention if such symptoms occur. Furthermore, it is crucial to understand that an overdose of insulin can lead to too low blood sugar levels (hypoglycemia) and require immediate medical attention. Symptoms of low blood sugar may occur even with regular use of insulin. It is essential to have a source of sugar or candy accessible at all times to help prevent hypoglycemia and always consult a medical professional for guidance on proper management of diabetes and insulin intake. If emergency symptoms occur, it is advised to call 911 or immediately go to the nearest emergency room. Please note, immediate medical attention is necessary for severe hypoglycemia.

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  • Missed Dose

    If you have missed a dose of human insulin RDNA 100IU/ml, it is important to take the missed dose as soon as possible. However, if it is close to the time for your next dose, it is best to skip the missed dose and resume your normal schedule. This is to avoid doubling up on insulin doses, as it can lead to adverse reactions. If you are unsure about how to proceed, it is recommended to consult with your physician or nurse practitioner for appropriate advice and guidance on when and how much to take.

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  • How To Use

    Prior to using Human Insulin rDNA 100IU/ml, it is crucial to understand the product information and proper injection techniques to ensure its safe and effective use. This involves reading the Patient Information Leaflet and following the instructions for proper use, paying attention to the safety information and correct injection techniques.In preparation for the injection, you should first examine the insulin bottle carefully for any particles or discoloration. If anything appears wrong, dispose of the insulin properly. You should also ensure the needle is not bent and is the correct size for the injection. It is essential to never use a reused or incorrect needle. The dosage of insulin depends on individual requirements, which are usually determined by a healthcare provider. These dosage guidelines are often based on factors such as glucose levels, age, weight, and meal patterns. Selecting a suitable injection site is also important, which should be rotated regularly between the thigh, stomach, buttocks, or the back of the upper arm. Each subsequent injection site should be at least one inch away from the previous spot. If using a prefilled insulin pen, it should be refrigerated before use, and caution should be taken to avoid excessive heat. The needle cover should be removed using the needle remover tool or by firmly holding the pen. It is never recommended to reuse or share needles. Finally, when administering the insulin injection, stabilize the insulin bottle or pen by tucking it into your palm. Pinch the skin at the injection site, swiftly insert the needle at a 90-degree angle, and then remove the needle. Applying gentle pressure to the injection site with sterile gauze or tissue prevents leakage and bruising.

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  • When Not to Use

    Discerning instances where this medication may not be appropriate:

    • You are allergic to human insulin or any of its ingredients. It is important to always read the patient information leaflet and inform your doctor of any allergy symptoms.
    • Your blood sugar levels are too low or you are experiencing severe hypoglycemia. It is advised to consume a fast-acting source of glucose, such as glucose tablets, candy, or fruit juice. If your blood sugar level is below 70 mg/dL or you experience severe symptoms such as unconsciousness, it is important to seek medical attention immediately.
    • You have an acute illness or an acute infection that causes high fever or hypoglycemia. It is advised to consult with a healthcare professional before adjusting your insulin dose. They may provide guidance on adjusting your dosing schedule or provide alternative treatment options.
    • You are experiencing severe liver or kidney disease or impairment. It is important to inform your doctor of any impairments or changes, so they can advise you on whether any dosage adjustments are needed and provide further guidance.
    • You are pregnant, planning to become pregnant, or breastfeeding. It is important to consult with a healthcare professional who can assess and discuss the potential benefits and risks associated with using insulin during pregnancy, based on your individual medical history and condition.
    • Your blood sugar levels are high and you are experiencing ketoacidosis. If your blood sugar levels have been rising, it is crucial to seek medical attention as untreated ketoacidosis can be severe and even life-threatening.

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  • Side Effects

    Unraveling the side effects lurking behind this medications are as follows:

    • Weight gain
    • Injection site reactions (redness, swelling, or itching)
    • Allergic reactions (rarely)
    • Lipodystrophy (fat tissue changes at injection sites)
    • Hypokalemia (low potassium levels)
    • Headache
    • Nausea

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  • Precautions & Warnings

    When using regular insulin, it's important to consider the following warnings and precautions:

    • Drug interactions can occur with various medications, potentially affecting insulin efficacy or increasing the risk of side effects.
    • Hypoglycemia, or low blood sugar, may happen, leading to dangerously low blood glucose levels.
    • Sharing needles should be avoided to minimize the risk of infection.
    • Allergic reactions to regular insulin can affect the entire body and require immediate medical attention.
    • Alcohol consumption can significantly lower blood sugar levels, making it unsafe for those using regular insulin.
    • Careful management of carbohydrate intake is essential, as consuming too many or too few can cause blood sugar fluctuations; skipping meals should be avoided.
    • It is crucial to discuss any other ongoing health conditions with a doctor before starting regular insulin to ensure proper management and prevent complications.

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  • Drug Interactions

    Drug interactions with regular human insulin include:

    • Oral hypoglycemics (e.g., metformin, sulfonylureas) (may require adjustment of insulin dosage)
    • Beta-blockers (e.g., propranolol) (may mask hypoglycemic symptoms)
    • ACE inhibitors (e.g., lisinopril) (may enhance the hypoglycemic effect of insulin)
    • Diuretics (e.g., furosemide) (may affect blood glucose control)
    • Corticosteroids (e.g., prednisone) (may increase insulin requirements)
    • Alcohol (may increase the risk of hypoglycemia)

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  • Storage/Disposal

    Human Insulin rDNA 100IU/ml should be stored in a refrigerator at a temperature of 2-8°C (36-46°F). The insulin should be kept in its original container and tightly sealed to keep it safe from moisture and out of the freezer compartment. Prior to use, the vial should be gently rotated to mix the insulin, as the substance may separate during storage. It is recommended to consult a healthcare professional for guidance on storage practices and expiration dates because these vary depending on the specific product and conditions. It is also suggested that the insulin not be stored near the refrigerator door, as the temperature near the door is not consistently cold enough. A healthcare provider can offer guidance on proper storage practices and expiration dates.

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