Intig (830mg) 30 Tablets

Intig (830mg) 30 Tablets

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  • Manufacturer SAMI Pharmaceuticals (Pvt.) Ltd.
  • Generic Name

    Calcitriol, Ossein Mineral complex

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Product Information

  • Description
  • Ingredients
  • Drug Class
  • Dosage Form
  • Uses
  • In case of Overdose
  • Missed Dose
  • How To Use
  • When Not to Use
  • Side Effects
  • Precautions & Warnings
  • Drug Interactions
  • Food Interactions
  • Storage/Disposal
  • Quick Tips, if any
  • Description

    Calcitriol, a synthetic form of vitamin D, and Ossein Mineral Complex Tablet work synergistically to support bone health. Calcitriol primarily acts by binding to the vitamin D receptors in the body, which are present in various tissues, including the intestines, bones, and kidneys. This binding activates specific genes that regulate calcium and phosphate metabolism. One of its key actions is enhancing the absorption of calcium and phosphate in the intestines, allowing for increased calcium uptake into the bloodstream. The Ossein Mineral Complex, derived from ossein (a protein matrix found in bones), provides a rich source of essential minerals, including calcium and phosphorus. When combined with calcitriol, these minerals are more efficiently absorbed and utilized by the body, promoting bone mineralization and overall bone strength. This dual mechanism of action helps maintain optimal bone density and reduces the risk of osteoporosis.

  • Ingredients

    Calcitriol, Ossein Mineral complex

  • Drug Class

    Vitamin D analog and Mineral supplement

  • Dosage Form

    Tablet

  • Uses

    The following are the uses of Calcitriol, Ossein Mineral complex Tablet:

    • Used for treating and preventing osteoporosis, ensuring strong and healthy bones.
    • Used for managing postmenopausal osteoporosis, addressing calcium deficiencies.
    • Used to regulate calcium and phosphate levels, promoting bone health.
    • Used in cases of vitamin D deficiency, ensuring proper bone mineralization.
    • Used to support bone growth and development, especially in children.
    • Used for preventing fractures and improving bone density.
    • Used as a supplement for individuals with malabsorption issues.
    • Used to enhance calcium absorption, contributing to overall bone strength.
  • In case of Overdose

    In the case of an overdose of Calcitriol and Ossein Mineral Complex Tablet, individuals may experience symptoms such as nausea, vomiting, constipation, and increased thirst. Additionally, severe cases of overdose can lead to elevated calcium levels in the blood, resulting in potential complications like kidney damage, bone pain, and fatigue. Prompt medical intervention is necessary to manage these symptoms and prevent further health risks associated with the overdose.

  • Missed Dose

    In the case of a missed dose of Calcitriol, it is recommended to take the medication as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. For Ossein Mineral Complex Tablet, if you miss a dose, take it as soon as you remember, but if it is closer to your next dose, skip the missed dose and continue with your regular dosing. Do not take extra tablets to compensate for the missed dose.

  • How To Use

    To take the Calcitriol, Ossein Mineral Complex Tablet, swallow the tablet whole with a full glass of water, preferably with a meal or as directed by your healthcare professional, following the prescribed dosage and schedule provided by your doctor.

  • When Not to Use

    Following are the conditions/situations when Calcitriol, Ossein Mineral Complex Tablet should not be used:

    • Must not be used in individuals with a known hypersensitivity or allergy to Calcitriol, Vitamin D analogs, or any of the excipients in the tablet.
    • Contraindicated in patients with hypercalcemia (high levels of calcium in the blood) or conditions causing hypercalcemia such as primary hyperparathyroidism.
    • Should not be used in patients with evidence of vitamin D toxicity.
    • Not suitable for individuals with elevated calcium levels in urine (hypercalciuria) and a history of kidney stones.
    • Contraindicated in patients with impaired kidney function or those on dialysis.
    • Should be avoided in conditions where calcium levels are not properly regulated, such as sarcoidosis, histoplasmosis, and overactive parathyroid glands.
    • Not recommended for individuals with conditions causing excessive bone resorption, such as hyperparathyroidism or Paget's disease.
  • Side Effects

    The side effects of Calcitriol, Ossein Mineral Complex Tablet may include:

    • Nausea and vomiting
    • Constipation or diarrhea
    • Weakness or fatigue
    • Dry mouth
    • Increased thirst
    • Muscle or joint pain
    • Elevated calcium levels in the blood (hypercalcemia), which may lead to symptoms like confusion, loss of appetite, and frequent urination
    • Allergic reactions such as rash, itching, or difficulty breathing
  • Precautions & Warnings

    Following are the precautions and warnings for Calcitriol, Ossein Mineral Complex Tablet:

    • This medication should be used with caution in patients with kidney disease, as it can cause a rise in calcium levels, potentially leading to serious complications.
    • Regular monitoring of calcium levels in the blood is essential during treatment, and dosage adjustments may be necessary.
    • Not recommended for individuals with hypercalcemia (high calcium levels) or those with a history of hypercalcemia.
    • Patients with a history of kidney stones or calcium-based kidney problems should exercise caution, as this medication may increase the risk of stone formation.
    • It may cause dizziness or drowsiness, so patients should avoid activities that require mental alertness until they know how the medication affects them.
    • Not suitable for individuals with a known allergy to calcitriol or any of the tablet's components.
    • The long-term use of this medication should be monitored closely by a healthcare professional, as it may lead to an increased risk of side effects.
    • Patients should maintain adequate hydration and follow a balanced diet to support the medication's effectiveness and reduce the risk of side effects.
  • Drug Interactions

    Following are the drug interactions for Calcitriol, Ossein Mineral Complex Tablet:

    • Thiazide diuretics can increase the risk of hypercalcemia when used with Calcitriol, requiring close monitoring of calcium levels.
    • Anticonvulsants like phenytoin and phenobarbital may reduce the effectiveness of Calcitriol by increasing its metabolism.
    • Corticosteroids can cause bone loss and increase the demand for vitamin D, requiring careful monitoring of vitamin D and calcium levels.
    • Cholestyramine and colestipol can decrease the absorption of Calcitriol, reducing its effectiveness.
    • Taking Calcitriol with aluminum-containing antacids may decrease the absorption of both medications.
    • The effects of digoxin may be enhanced by Calcitriol, requiring close monitoring of digoxin levels.
    • Mineral oil laxatives can reduce the absorption of vitamin D and its metabolites, including Calcitriol.
  • Food Interactions

    Following are the food interactions for Calcitriol, Ossein Mineral Complex Tablet:

    • High-calcium foods like milk, cheese, yogurt, and calcium-fortified foods should be consumed in moderation as excessive intake can lead to hypercalcemia when combined with the medication.
    • Phosphate-rich foods such as meat, fish, eggs, and whole grains may require monitoring as this medication can affect phosphate metabolism.
    • Vitamin D-fortified foods, including certain types of milk, orange juice, and cereals, should be consumed in moderation to avoid excessive vitamin D intake.
    • Alcohol should be avoided as it may negatively impact bone metabolism and potentially interfere with the medication's effectiveness.
    • Grapefruit and grapefruit juice are generally safe with this medication, but they may affect liver enzymes and should be consumed in moderation.
    • Foods rich in magnesium, such as leafy greens, nuts, and seeds, can be beneficial as they support bone health, but excessive intake may require monitoring.
    • A balanced diet with a variety of fruits, vegetables, and lean proteins is recommended to ensure overall health and optimal medication absorption.
    • It is advisable to consult a healthcare professional for personalized dietary advice based on your specific needs and medical condition.
  • Storage/Disposal

    Calcitriol, Ossein Mineral Complex Tablets should be stored in a cool, dry location, preferably at room temperature, ensuring protection from light and moisture. The original container should be tightly sealed to maintain its integrity and prevent contamination. It is crucial not to store the tablets in the bathroom or near heat-emitting appliances like ovens or heaters, as these environments can compromise the medication's quality. Dispose of any unused or expired tablets responsibly; refrain from flushing them down the toilet or disposing of them in sinks. Consult your pharmacist or healthcare professional for appropriate disposal methods. Keep the medication away from children to prevent accidental ingestion.

  • Quick Tips, if any

    Following are the quick tips for Calcitriol, Ossein Mineral Complex Tablet:

    • Consult your doctor before taking this medication, especially if you have kidney or liver problems.
    • Take the tablet as directed by your healthcare provider, usually once a day.
    • Swallow the tablet whole with a full glass of water, preferably at the same time each day.
    • Avoid taking other vitamin D supplements unless advised by your doctor.
    • Regularly monitor your calcium levels while on this medication.
    • Do not crush or chew the tablet; ensure proper tablet intake.
    • Store the medication in a cool, dry place, away from direct sunlight.

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