IreCon (75mg) 10 Tablets

Irbesartan is an angiotensin II receptor blocker (ARB) that selectively blocks the binding of angiotensin II to AT1 receptors, which are found in many tissues, including vascular smooth muscle and the adrenal glands. Angiotensin II is a potent vasoconstrictor, and by blocking its effects, irbesartan inhibits the vasoconstrictive and aldosterone-secreting effects of angiotensin II. This leads to a decrease in peripheral vascular resistance, resulting in reduced blood pressure. Irbesartan's mechanism of action primarily involves promoting vasodilation, which helps to lower blood pressure by relaxing the blood vessels and improving blood flow.

Irbesartan 75MG

Angiotensin II Receptor Blocker

Tablet

The following are the uses of Irbesartan 75MG Tablet:

• Used for treating high blood pressure, helping to prevent serious conditions like strokes and heart attacks.
• Used to reduce the risk of heart-related issues in diabetic patients, protecting the kidneys and heart.
• Used for managing hypertension, improving blood flow, and easing the heart's workload.
• Used to slow down the progression of kidney disease, especially in diabetic patients.
• Used for lowering blood pressure, reducing strain on the heart and arteries.
• Used in treating heart failure, improving symptoms and enhancing overall heart function.
• Used to increase blood flow to the kidneys, supporting kidney function.
• Used to prevent the worsening of cardiovascular conditions, promoting long-term heart health.

Follow these dosage instructions:

• Initial therapy

Hydrochlorothiazide 12.5 mg-Irbesartan 150 mg orally once a day; may increase after 1 to 2 weeks.

• Replacement Therapy

Hydrochlorothiazide 12.5 to 25 mg-Irbesartan 150 to 300 mg orally once a day

• Maximum dose

Hydrochlorothiazide 25 mg-Irbesartan 300 mg orally once a day

In the case of an overdose of Irbesartan 75MG Tablets, individuals may experience symptoms such as dizziness, increased heart rate, and a sudden drop in blood pressure. It is crucial to remain calm and contact a healthcare professional or poison control center immediately for guidance. They will provide specific instructions to manage the overdose, which may include inducing vomiting or administering activated charcoal to prevent further absorption of the medication. Quick action and medical advice are essential in these situations.

In the case of a missed dose of Irbesartan 75MG Tablet, it is recommended to take the missed dose as soon as you remember. However, if it's close to the time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. It is generally advised not to double the dose to make up for a missed one. If you miss multiple doses, contact your healthcare provider for guidance on how to safely resume your medication regimen without compromising its effectiveness.

To take Irbesartan 75MG Tablet, swallow the tablet whole with a glass of water, preferably at the same time each day, as directed by your healthcare provider, typically once daily, with or without food.

Following are the conditions when Irbesartan 75MG Tablet should not be taken:

• Should not be taken if you are allergic to Irbesartan or any other angiotensin II receptor blockers (ARBs).
• Not suitable for individuals with a rare genetic problem of galactose intolerance, severe lactase deficiency, or glucose-galactose malabsorption.
• Contraindicated in pregnant women, especially during the second and third trimesters, as it can cause harm to the fetus.
• Should not be used in individuals with severe liver disease or biliary obstruction.
• Not recommended for individuals with severe vomiting, diarrhea, or excessive sweating, as it may lead to dehydration.
• Do not take if you have a history of angioedema (swelling of the face, lips, throat, or tongue) after taking Irbesartan or other similar medications.
• Contraindicated in individuals with severe kidney problems or those who are dependent on dialysis.

The side effects of Irbesartan 75MG Tablet may include:

• Dizziness
• Fatigue or tiredness
• Diarrhea
• Nausea and vomiting
• Muscle cramps
• Increased potassium levels in the blood (hyperkalemia)
• Joint pain
• Skin rashes

Following are the precautions and warnings for Irbesartan 75MG Tablet:

• This medication should not be used in patients with a known allergy or hypersensitivity to Irbesartan or any other angiotensin II receptor blockers.
• Patients with a history of liver problems should exercise caution and inform their doctor, as Irbesartan may affect liver function.
• Irbesartan can cause dizziness and lightheadedness, especially when standing up from a sitting or lying position. Elderly patients should be cautious to avoid falls.
• It may cause an excessive drop in blood pressure in patients with reduced fluid volume or those receiving diuretic therapy. Close monitoring is necessary.
• Patients with a history of kidney disease or those on dialysis should be closely monitored, as Irbesartan is primarily excreted by the kidneys.
• This medication is not recommended during pregnancy, especially in the second and third trimesters, as it may cause harm to the fetus.
• Women who are breastfeeding should consult their doctor, as Irbesartan may pass into breast milk.
• Irbesartan may interact with other medications, including diuretics, NSAIDs, and potassium supplements, so patients should inform their doctor of all medications they are taking.

Following are the drug interactions for Irbesartan 75MG Tablet:

• Lithium levels may be increased when used with Irbesartan, leading to lithium toxicity. Close monitoring of lithium levels is necessary.
• The blood pressure-lowering effect of Irbesartan can be reduced by NSAIDs (non-steroidal anti-inflammatory drugs) like ibuprofen.
• When combined with diuretics, particularly potassium-sparing diuretics, Irbesartan may cause hyperkalemia (high potassium levels).
• The antihypertensive effect of Irbesartan may be enhanced by other antihypertensive medications, potentially causing excessive blood pressure drop.
• Irbesartan may increase serum digoxin levels, requiring careful monitoring.
• The risk of angioedema, a serious allergic reaction, is higher when Irbesartan is used with ACE inhibitors.
• The effectiveness of Irbesartan may be reduced when taken with NSAIDs and ARBs (angiotensin II receptor blockers).

Following are the food interactions to be aware of when taking Irbesartan 75MG Tablet:

• Grapefruit and grapefruit juice consumption should be avoided as they can increase the blood levels of Irbesartan, potentially leading to an increased risk of side effects related to the medication.
• Alcohol intake should be limited or avoided as it may decrease blood pressure further, causing excessive drops in blood pressure, especially when standing from a sitting or lying position.
• Avoid high-sodium foods as Irbesartan reduces the body's ability to eliminate sodium, and high sodium intake can counteract the medication's effectiveness in controlling blood pressure.
• Potassium-rich foods like bananas, oranges, and spinach should be consumed in moderation as Irbesartan can increase potassium levels, and excessive potassium can lead to irregular heart rhythms.
• Licorice, a natural sweetener, should be avoided as it may decrease the effectiveness of Irbesartan in lowering blood pressure.
• Maintain a balanced diet, focusing on whole grains, fruits, vegetables, and lean proteins, to support overall health and blood pressure management.
• Stay well-hydrated by drinking adequate water to maintain kidney function and facilitate the medication's excretion.
• Avoid excessive caffeine intake as it may counteract the blood pressure-lowering effects of Irbesartan.

Irbesartan 75MG Tablets should be stored in a secure and dry location, preferably in a medicine cabinet, at room temperature (68°F to 77°F). Protect the tablets from light and moisture by keeping them in their original container with the lid tightly sealed. It's crucial not to expose the medication to extreme temperatures or humidity, so avoid storing it in the bathroom or near the kitchen stove. Always check the expiration date, and if the tablets are past their prime or no longer needed, proper disposal is essential. Do not throw them into the trash or flush them down the toilet. Consult your pharmacist or healthcare provider for guidance on safe disposal methods to protect the environment and prevent misuse. Keep the medication out of children's reach to ensure their safety.

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Following are the quick tips for Irbesartan 75MG Tablet:

• Take the tablet as directed by your doctor, usually once daily.
• Consistency is key; take it at the same time each day for best results.
• Swallow the tablet whole with a full glass of water; do not crush or chew.
• It can be taken with or without food, but be consistent with your choice.
• If you miss a dose, take it as soon as you remember, unless it's close to your next dose.
• Inform your doctor about all medications you're taking to avoid potential interactions.
• Store Irbesartan at room temperature, away from moisture and light.