Izato (500mg) 20 Tablets

Izato (500mg) 20 Tablets

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  • Manufacturer SAMI Pharmaceuticals (Pvt.) Ltd.
  • Generic Name Nitazoxanide

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Product Information

  • Description
  • Ingredients
  • Drug Class
  • Dosage Form
  • Uses
  • Dosage
  • In case of Overdose
  • Missed Dose
  • How To Use
  • When Not to Use
  • Side Effects
  • Precautions & Warnings
  • Drug Interactions
  • Food Interactions
  • Storage/Disposal
  • Description

    Nitazoxanide is an anti-protozoal drug used to treat infections caused by parasites. It prevents the growth and reproduction of microorganisms by restricting the production of nucleic acids, which are essential for the survival of these parasites. It is active against many protozoa, specifically Giardia lamblia, Cryptosporidium parvum, and Entamoeba histolytica. Additionally, Nitazoxanide is effective against certain bacteria, such as Salmonella and Listeria. Besides its anti-microbial properties, Nitazoxanide also possesses antiviral properties. It has been used to treat viral infections such as chronic hepatitis C and Ebola virus infection. The exact process behind its antiviral activity is not entirely understood, but it is believed that Nitazoxanide inhibits the creation of viral nucleic acids and stimulates the immune system to reduce viral loads. Overall, Nitazoxanide is a versatile anti-microbial agent that influences nucleic acid synthesis to inhibit the growth and reproduction of various microorganisms, including protozoa, bacteria, and viruses.

  • Ingredients

    Nitazoxanide
  • Drug Class

    Anti-Protozal Agent

  • Dosage Form

    Tablet
  • Uses

    Unveiling its multifaceted uses and transformative applications as follows:

    • Treats a variety of parasitic infections, especially those caused by protozoa like Giardia.
    • Decreases inflammation and improves symptoms of diarrhea.
    • Helps with parasitic infections that have resisted treatment with other medications.
    • Useful for treating parasites that live in the intestines.
    • Helps maintain healthy gut function.
    • Increasingly used for the treatment of COVID-19.
    • Reduces manifestations of COVID-19 related pneumonia especially in adult patients.
  • Dosage

    Tailoring Treatment for Optimal Health, Prescribed Medication Dosage is:

    • Adults and children above 12 years of age- Take 500 mg twice a day for 3 days.
    • Children aged 1 to < 12 years- Take 500 mg once a day for 3 days.
    • Children aged < 1 year- 5 mg/kg/day once a day for 3 days.
  • In case of Overdose

    An overdose of Nitazoxanide 500mg may result in adverse effects on the liver, kidneys, or pancreas. These may include allergic reactions, elevated serum transaminase, and nausea. These side effects are not inclusive of all potential side effects, and to understand more, please consult a medical professional. If you are experiencing any adverse effects, it is recommended to contact your doctor or emergency services immediately. This information is not a substitute for professional medical advice and should only be used for general knowledge.

  • Missed Dose

    It is crucial to adhere to the prescribed dosage of Nitazoxanide 500mg to ensure its effectiveness. If you miss a dose, you should take it as soon as you remember, preferably immediately or at the next scheduled interval. However, if it is almost time for the next dose, you should skip the missed dose and follow the regular schedule. To avoid any potential complications, consult your doctor or pharmacist for guidance on how to handle a missed dose and prevent double dosing. They can provide personalized advice based on your medical condition and any other medications you may be taking.

  • How To Use

    Before taking Nitazoxanide, it is important to consider the following instructions and precautions to ensure safe and effective use. Nitazoxanide is suitable for adults and children aged one and above. Since the dosage depends on each individual's weight and age, it is vital to follow the healthcare provider's instructions carefully. To make sure you understand how to use Nitazoxanide effectively, consider the following guidelines:

  • When Not to Use

    Discerning instances where this medication may not be appropriate:

    • You are allergic to Nitazoxanide or any of its ingredients. It is important to inform your doctor of any drug allergies you may have before beginning any new medication.
    • You have severe liver disease or kidney disease. This is because Nitazoxanide can be harsh on the kidneys and may exacerbate pre-existing kidney conditions. Similarly, the drug is metabolized through the liver and can place undue stress on the organ if it is already compromised.
    • You have a history of quinolone antibiotic use and experienced any concerning side effects. Nitazoxanide belongs to the same family of drugs as the quinolones and may carry similar risks.
    • You are pregnant or planning to become pregnant. While rare, there is some risk of birth defects associated with Nitazoxanide. It is therefore not typically prescribed to pregnant women, or to women planning to become pregnant, unless the benefits outweigh the risks.
    • You have a history of tendon problems or experiencing pain in your joints. This is a rare side effect of Nitazoxanide and an important consideration for those who have had tendon issues in the past.
    • You have a planned surgery or medical procedure. It is important to inform your medical team about all medications you are on before undergoing any procedure. In the case of Nitazoxanide, it may be temporarily discontinued depending on the nature of the surgery.
  • Side Effects

    Unraveling the side effects lurking behind this medications are as follows:

    • Gastrointestinal Symptoms
    • Dizziness and Headaches
    • Central Nervous System Symptoms
    • Allergic Reactions
    • Liver Toxicity
  • Precautions & Warnings

    The warnings and precautions for Nitazoxanide are:

    • Patient with HIV and immunodeficiency
    • Pregnancy and lactation
  • Drug Interactions

    The drug interactions with nitazoxanide include:

    • Antacids – Can decrease nitazoxanide absorption.
    • Other Antiprotozoals – Can have additive effects.
  • Food Interactions

    The food interactions that should be considered while using Nitazoxanide are:

    • No significant interactions with food.
    • Taking with food may enhance absorption.
  • Storage/Disposal

    Nitazoxanide is a valuable medication used to treat intestinal infections and symptoms of diarrhea. To ensure maximum effectiveness and safety, it is crucial to adhere to the manufacturer's guidelines and storage instructions provided by your healthcare provider. Storing Nitazoxanide correctly involves keeping it in a cool, dry location, such as a cabinet or drawer, away from direct heat or light. It is important to avoid humid areas, including bathrooms, as well as freezing temperatures, as these conditions can degrade the medication's effectiveness. To prevent accidental consumption, especially by children, it is essential to keep Nitazoxanide and all other medications out of reach. Discarding the medication after the expiration date has passed is necessary to ensure safety and potency. Following these storage guidelines will help ensure that Nitazoxanide remains safe and effective until it is time to take it. Nevertheless, it is always beneficial to consult with a healthcare professional if you have any specific questions or concerns regarding how to store Nitazoxanide, keeping in mind that instructions may vary depending on the product and location.

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