Hamdard Jernide 120ml Syrup

The primary mechanism of action of Glycyrrhiza Glabra Syrup/Suspension is attributed to its key component, glycyrrhizic acid, which is responsible for most of the pharmacological effects. Glycyrrhizic acid acts by inhibiting the enzyme 11-beta-hydroxysteroid dehydrogenase (11β-HSD), leading to increased levels of the active cortisol in the body. This elevation in cortisol has anti-inflammatory and immunomodulatory effects, helping to reduce inflammation and modulate the immune response. Additionally, glycyrrhizic acid has mucolytic properties, meaning it can help thin and loosen mucus, making it easier to expel, which is beneficial for respiratory conditions. It also exhibits expectorant effects, stimulating the production of respiratory tract secretions, aiding in the clearance of mucus and easing congestion.

Glycyrrhiza Glabra

Expectorant.

Suspension

The following are the uses of Glycyrrhiza Glabra Syrup/Suspension:

• Used for relieving cough and soothing throat irritation due to its expectorant and demulcent properties.
• Used for treating digestive issues such as stomach ulcers and gastritis, as it can help protect the stomach lining.
• Used for managing respiratory conditions like bronchitis and asthma by reducing inflammation in the airways.
• Used for skin conditions, including eczema and psoriasis, due to its anti-inflammatory and soothing effects.
• Used for alleviating symptoms of menopause, such as hot flashes, due to its estrogen-like compounds.
• Used for flavoring and sweetening various pharmaceutical products, making medications more palatable.
• Used for its potential antiviral and antimicrobial effects, showing activity against certain viruses and bacteria.
• Used for supporting liver health and aiding in detoxification processes.

In the case of an overdose of Glycyrrhiza Glabra Syrup/Suspension, it is important to recognize the potential symptoms. These may include irregular heartbeat, high blood pressure, and muscle weakness. Prompt action should be taken, such as contacting a healthcare professional or a poison control center for guidance on managing the overdose. Quick response and appropriate medical care are essential in such situations.

In the case of a missed dose of Glycyrrhiza Glabra Syrup/Suspension, it is generally advised to take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one, as this may increase the risk of side effects. If you miss multiple doses, consult your healthcare professional for guidance on how to get back on track with your medication regimen.

To use Glycyrrhiza Glabra Syrup/Suspension, shake the bottle well, measure the prescribed dose with a measuring device, and take it orally as directed by your healthcare provider, typically once or twice a day, with or without food, following the dosage instructions provided.

Following are the conditions/situations when Glycyrrhiza Glabra Syrup/Suspension should not be used:

• Not suitable for individuals with a known allergy or hypersensitivity to licorice root or any of its constituents.
• Contraindicated in patients with high blood pressure (hypertension) as it can further elevate blood pressure levels.
• Should be avoided in individuals with heart-related conditions such as congestive heart failure or irregular heartbeat.
• Not recommended for long-term use due to the potential risk of pseudoaldosteronism and hypokalemia.
• Contraindicated in pregnant women as it may cause adverse effects on the developing fetus.
• Should not be used by breastfeeding mothers as it can pass into breast milk and potentially affect the infant.
• Not suitable for individuals with kidney disease or those taking diuretics, as it can disrupt the body's fluid balance.
• Avoid use if you have low potassium levels (hypokalemia) or are taking potassium-depleting medications.

The side effects of Glycyrrhiza Glabra Syrup/Suspension may include:

• Increased blood pressure
• Hypokalemia (low potassium levels)
• Fluid retention and swelling (edema)
• Headaches
• Fatigue or muscle weakness
• Irregular heartbeat
• Electrolyte imbalances
• Gastrointestinal issues like nausea or stomach discomfort

Following are the precautions and warnings for Glycyrrhiza Glabra Syrup/Suspension:

• Avoid use if you are allergic to licorice root or any related plants, as it may trigger an allergic reaction.
• This syrup should be used with caution in patients with high blood pressure, as it can cause sodium and water retention, potentially leading to increased blood pressure.
• Glycyrrhiza Glabra can interact with certain medications, including diuretics, corticosteroids, and insulin, so consult your doctor if you are on any medications.
• Not recommended for long-term use due to the potential for hypokalemia and increased blood pressure.
• Avoid excessive consumption, as it may lead to electrolyte imbalances and other health issues.
• Pregnant and breastfeeding women should consult a healthcare professional before use, as it may affect hormone levels.
• Keep out of reach of children, and store in a cool, dry place away from direct sunlight.

Following are the drug interactions for Glycyrrhiza Glabra Syrup/Suspension:

• Licorice can decrease the elimination of caffeine, potentially increasing its stimulant effects and the risk of caffeine-related side effects.
• It may reduce the effectiveness of oral contraceptives, potentially impacting birth control.
• Interactions with diuretic medications can increase potassium loss, leading to hypokalemia.
• Glycyrrhizin in licorice can decrease the metabolism of certain medications, including digoxin, leading to increased drug levels and potential toxicity.
• Licorice can enhance the effects of corticosteroids, potentially causing excessive corticosteroid-related side effects.
• The use of licorice with insulin or oral hypoglycemic drugs may increase the risk of hypokalemia, a condition with low potassium levels.
• It may interfere with the absorption of certain antibiotics, potentially reducing their effectiveness.

Following are the food interactions for Glycyrrhiza Glabra Syrup/Suspension:

• Licorice root, the primary ingredient, can interact with foods containing tyramine, such as aged cheeses, cured meats, and certain types of beer, as it may elevate blood pressure.
• Consuming excessive amounts of licorice-containing foods while taking this syrup can lead to increased blood pressure and potassium depletion.
• Grapefruit juice should be consumed with caution as it may affect the metabolism of certain compounds in the syrup.
• Avoid excessive consumption of salt or salty foods, as licorice can affect sodium and water retention.
• Limit or avoid caffeine-rich foods and beverages, as licorice can enhance the effects of caffeine, potentially causing nervousness and increased heart rate.
• Be cautious with high-potassium foods like bananas, oranges, and spinach, as licorice can cause potassium levels to drop.
• Alcohol may intensify the effects of Glycyrrhiza Glabra, potentially affecting the nervous system and increasing sedation.
• Always consult a healthcare professional for personalized advice regarding specific food interactions and dietary considerations.

Glycyrrhiza Glabra Syrup/Suspension requires proper storage and disposal to maintain its integrity and ensure safety. Store the medication in a cool, dry area at room temperature, ensuring protection from direct sunlight and moisture. Keep the container tightly sealed to prevent contamination. Avoid storage in bathrooms or near heat sources like stoves or radiators, as temperature fluctuations can impact the syrup's quality. Dispose of any unused or expired syrup responsibly; refrain from flushing it or pouring it down the drain. Consult your pharmacist or healthcare professional for guidance on appropriate disposal methods. Lastly, store the medication in a secure location, inaccessible to children, to prevent accidental consumption.

Following are the quick tips for Glycyrrhiza Glabra Syrup/Suspension:

• Follow the dosage instructions provided by your healthcare professional for the best results.
• Before each use, give the bottle a good shake to ensure a consistent mixture.
• Administer the syrup with water; avoid tea, coffee, or dairy for better absorption.
• Maintain a consistent routine by taking your dose at the same time daily.
• If stomach irritation occurs, consider taking the syrup with food to alleviate discomfort.
• Store the syrup safely, keeping it out of children's reach.
• Consult your doctor if you have any concerns or experience unusual symptoms.