KALDIC SR 100MG TAB

Serratiopeptidase is a proteolytic enzyme that exhibits anti-inflammatory and analgesic properties. Its mechanism of action involves breaking down and reducing the levels of inflammatory mediators, such as bradykinin, prostaglandins, and fibrin, which are involved in pain and inflammation. Serratiopeptidase helps reduce swelling, improve blood flow to the affected area, and facilitate the removal of dead or damaged tissue. Diclofenac Potassium, on the other hand, is a non-steroidal anti-inflammatory drug (NSAID) that inhibits the enzyme cyclooxygenase (COX), particularly COX-2. By blocking COX enzymes, Diclofenac Potassium reduces the production of prostaglandins, which are responsible for pain, inflammation, and fever. This inhibition of prostaglandin synthesis is the primary mechanism through which Diclofenac Potassium exerts its analgesic, anti-inflammatory, and antipyretic effects.

Proteolytic enzyme and NSAID (Non-steroidal anti-inflammatory drug)

Tablet

The following are the uses of Serratiopeptidase, Diclofenac Potassium Tablet:

• Used for reducing inflammation and relieving pain, especially in conditions like arthritis.
• Used for treating acute pain and inflammation after injuries or surgery.
• Used for managing pain and swelling in conditions such as back pain, sprains, and strains.
• Used for reducing inflammation in the throat and providing pain relief in conditions like tonsillitis.
• Used for improving flexibility and reducing stiffness in joints.
• Used for managing pain and inflammation in dental procedures and oral surgeries.
• Used for its potential ability to break down blood clots and support cardiovascular health.
• Used for enhancing the effectiveness of pain management when combined with other medications.

In the case of an overdose of Serratiopeptidase and Diclofenac Potassium Tablets, the symptoms may vary depending on the individual's health and the amount ingested. Common signs include gastrointestinal issues such as nausea, vomiting, and abdominal pain. In more severe cases, individuals may experience dizziness, ringing in the ears, and in extreme cases, kidney or liver damage. It is crucial to seek medical assistance promptly and provide the healthcare provider with information regarding the dosage and timing of the overdose.

In the case of a missed dose of Serratiopeptidase and Diclofenac Potassium Tablet, it is generally recommended to take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one. If you miss multiple doses, contact your healthcare provider for advice on how to safely resume your medication and adjust your dosing schedule.

To take the Serratiopeptidase, Diclofenac Potassium Tablet, swallow the tablet whole with a glass of water, preferably after a meal, as directed by your healthcare professional, ensuring you follow the prescribed dosage and treatment duration for optimal results.

Following are the conditions or situations when Serratiopeptidase, Diclofenac Potassium Tablet should not be used:

• Avoid if allergic to Serratiopeptidase, Diclofenac, or any non-steroidal anti-inflammatory drugs (NSAIDs).
• Not recommended for individuals with a history of gastrointestinal bleeding or perforation.
• Should not be used in patients with severe heart failure or kidney disease.
• Contraindicated in individuals with active peptic ulcers or gastrointestinal bleeding.
• Avoid if you have a history of asthma or severe allergic reactions triggered by aspirin or other NSAIDs.
• Not suitable for patients with bleeding disorders or those taking blood-thinning medications.
• Should not be used in the last trimester of pregnancy.
• Contraindicated in individuals with severe liver impairment.
• Do not use if you have recently undergone coronary artery bypass graft (CABG) surgery.
• Avoid if you have inflammatory bowel disease (IBD) or systemic lupus erythematosus (SLE).

The side effects of Serratiopeptidase, Diclofenac Potassium Tablet may include:

• Nausea and vomiting
• Diarrhea
• Stomach pain or discomfort
• Heartburn or acid reflux
• Skin rash or itching
• Dizziness or vertigo
• Headache
• Increased blood pressure

Following are the precautions and warnings for Serratiopeptidase, Diclofenac Potassium Tablet:

• This medication should be used with caution in patients with a history of gastrointestinal bleeding, ulcers, or other stomach-related disorders, as it may increase the risk of gastrointestinal side effects.
• Patients with kidney or liver problems should be monitored closely as the dosage may need adjustment.
• Not recommended for individuals with heart-related issues, such as heart failure or cardiovascular disease, due to the potential impact of Diclofenac.
• Serratiopeptidase may cause allergic reactions; seek medical attention if you experience any symptoms such as rash, itching, or difficulty breathing.
• Elderly patients may be more sensitive to the effects of this medication and should be monitored for side effects.
• Consult your doctor if you have a history of asthma or allergic disorders before taking this medication.
• Avoid alcohol consumption while using this medication as it may increase the risk of gastrointestinal bleeding and liver toxicity.

Following are the drug interactions for Serratiopeptidase and Diclofenac Potassium Tablet:

• Serratiopeptidase may increase the absorption of Diclofenac, leading to higher blood levels and potentially increased side effects.
• The combination can increase the risk of gastrointestinal bleeding and ulcers, especially in elderly patients or those with a history of gastrointestinal disorders.
• Anticoagulants like Warfarin or other blood thinners may have their effects enhanced, requiring close monitoring of coagulation parameters.
• Diuretics and angiotensin-converting enzyme (ACE) inhibitors might have their blood pressure-lowering effects reduced when used with Diclofenac.
• Other non-steroidal anti-inflammatory drugs (NSAIDs) or corticosteroids may increase the risk of gastrointestinal toxicity and renal impairment.
• Methotrexate levels could be elevated, potentially increasing its toxicity, when used with Diclofenac.
• Lithium levels may be increased, leading to lithium toxicity, when used concurrently with Diclofenac.
• Serratiopeptidase may interact with other antibiotics, affecting their absorption and efficacy.

Following are the food interactions for Serratiopeptidase, Diclofenac Potassium Tablet:

• Alcohol should be consumed in moderation as it may increase the risk of gastrointestinal bleeding and liver-related side effects, especially when taken with Diclofenac.
• Avoid grapefruit and grapefruit juice as they can increase the levels of Diclofenac in the blood, potentially leading to an increased risk of side effects.
• Limit your intake of fatty foods, as Diclofenac is better absorbed with a light meal or snack, and high-fat meals may delay its absorption.
• Avoid excessive caffeine intake, as it may increase the risk of gastrointestinal irritation when combined with Diclofenac.
• There is no specific food interaction with Serratiopeptidase, but it's best to take it with a meal to enhance its absorption.
• Avoid spicy foods, as they may exacerbate gastrointestinal symptoms, especially when taking Diclofenac.
• Maintain a balanced diet, as Diclofenac may cause sodium and fluid retention, and monitoring your salt intake is advisable.

Serratiopeptidase, Diclofenac Potassium Tablets should be stored in a cool and dry place, preferably at room temperature (around 25°C/77°F). Protect the tablets from direct exposure to sunlight, moisture, and heat, as these conditions can degrade the medication. Keep the tablets in their original container, tightly sealed, to maintain their integrity and prevent contamination. It is crucial to dispose of any unused or expired tablets properly by returning them to a pharmacy or healthcare facility for safe disposal. Never flush medications down the toilet or pour them into a drain, as this can cause environmental harm. Always keep the medication out of the reach of children and pets to prevent accidental consumption.

Following are the quick tips for Serratiopeptidase and Diclofenac Potassium Tablet:

• Consult your doctor before taking these medications, especially if you have allergies or are pregnant/breastfeeding.
• Take these tablets as directed by your physician; do not exceed the prescribed dosage.
• Serratiopeptidase may be taken on an empty stomach, while Diclofenac Potassium is best taken with food to prevent stomach upset.
• Ensure you complete the full course of medication as prescribed.
• Avoid alcohol consumption while taking Diclofenac Potassium to reduce the risk of stomach bleeding.
• Store both medications at room temperature, away from moisture and direct sunlight.
• Do not share these medications with others, even if their symptoms are similar.