Klaricid XL (500mg) 5 Tablets

Clarithromycin is a macrolide antibiotic used to treat a variety of bacterial infections. It operates by inhibiting the protein synthesis of susceptible microorganisms, preventing bacterial cell formation, and promoting the death of these bacteria. This antibiotic is absorbed from the gastrointestinal tract and is excreted by the kidneys. It treats various bacterial infections of the skin and respiratory tract, pneumonia, gonorrhea, and Helicobacter pylori infection. It may also treat other conditions such as legionella pneumonia, pertussis, and Lyme disease. Clarithromycin continues to work against pathogens even if they have resistance mechanisms encoded in their genes because it is not efficiently exported from the cell due to its irreversible binding to its target, and its action against foreign molecules in the cell. Because of its broad spectrum of activity, ease of administration, and good clinical response, clarithromycin is a widely used antibiotic, but like many other antibiotics, can cause side effects such as nausea, vomiting, abdominal discomfort, and potentially abnormal liver function tests.

Macrolide Antibiotic

Unveiling its multifaceted uses and transformative applications as follows:

• Clarithromycin is a macrolide antibiotic that stops the growth of bacteria in the body.
• It is effective against a wide range of bacterial pathogens, some of which are resistant to other antibiotic agents.
• Can be used in the treatment of Lyme disease, pneumonia, bronchitis, and sinus infections.
• Useful in combination with other medications for the treatment of community-acquired pneumonia (CAP).

Tailoring Treatment for Optimal Health, Prescribed Medication Dosage is:

• Pneumonia- 500 mg every 12 hours for 7-14 days
• Skin and skin structure infections- 500 mg every 12 hours for 14-21 days
• Tonsillitis/upper respiratory tract infection- 500 mg every 12 hours for 7 days
• Sinusitis- 500 mg every 12 hours for 14 days
• Genitourinary tract infection- 500 mg every 12 hours for 7 days
• Helicobacter pylori infection- 500 mg twice a day for 7 days (in combination with other drugs)

An overdose of Clarithromycin 500mg can lead to unpleasant symptoms such as nausea, vomiting, abdominal pain, and diarrhea. These symptoms may indicate that the body has too much of the medication present, and thus it is essential to seek emergency medical attention promptly.Medical personnel may suggest interventions aimed at relieving symptoms by inducing vomiting or diarrhea to expel the excessive drug from the body. To mitigate adverse effects, additional treatments may be provided, along with the execution of supportive care measures consisting of hydration and efficient pain management.

Skipping a dose of Clarithromycin shouldn't be a problem, just take it as soon as you remember. But if it's almost time for your next dose, skip the missed dose and stay on your regular schedule. Don't take a double dose to make up for the missed one. If you're worried about missing a dose in the future, consult your pharmacist or healthcare provider for their recommendation. It's important to follow your treatment plan and discuss any questions or concerns with your healthcare provider.

Clarithromycin is a medication that is used to treat a variety of bacterial infections. It is important to understand how to properly take this medication in order to ensure its effectiveness and to avoid any potential side effects. Before starting your medication, be sure to read the medication guide provided by your pharmacist. If you have any concerns, ask your doctor or pharmacist. The tablets are typically taken once or twice a day, preferably at the same time each day. The specific dosage depends on individual factors such as age and the condition being treated. Clarithromycin can be taken with or without food, although taking it with food can help prevent an upset stomach. It is also important to drink plenty of fluids while taking Clarithromycin to prevent dehydration. If you miss a dose, take it as soon as you remember, as long as it is within a few hours of the missed dose. If it is closer to the time of your next dose, just skip the missed dose and resume your regular schedule. Do not double up on doses to make up for a missed one.

Discerning instances where this medication may not be appropriate:

• You are allergic to Clarithromycin or any other macrolide antibiotic.
• You have existing medical conditions such as liver or kidney disease.
• You are pregnant or breastfeeding.
• You are already taking certain other medications such as antiviral medicines, antidepressants, or drugs that suppress the immune system.

Unraveling the side effects lurking behind this medications are as follows:

• Abdominal pain
• Black stools
• Vomiting
• Fatigue
• Dizziness
• Dry mouth
• Nosebleed
• Increased sensitivity to sunlight

Here are some precautions and warnings for patients to be aware of:

• Patients with coronary artery disease (CAD), severe cardiac insufficiency, or clinically relevant bradycardia or conduction disturbances should be cautious.
• Those with myasthenia gravis should notify their healthcare provider.
• Patients taking other drugs known to prolong the QT interval (e.g. class IA or III antiarrhythmic agents) should be carefully monitored.
• Caution is advised for patients taking atazanavir or those with renal impairment taking atazanavir or ritonavir-containing regimens.
• Avoid using extended-release tablets in patients with a creatinine clearance (CrCl) <30 mL/min, as the dose cannot be reduced from 500 mg once daily.
• Caution should be exercised in patients with hepatic and moderate to severe renal impairment.
• Children and elderly individuals require special attention during treatment.
• Extra care should be taken during pregnancy and lactation.

Drug interactions with clarithromycin include:

• CYP3A4 inhibitors (e.g., ketoconazole, itraconazole) (may increase clarithromycin levels and risk of side effects)
• CYP3A4 inducers (e.g., rifampin) (may decrease clarithromycin levels and efficacy)
• Anticoagulants (e.g., warfarin) (may increase the risk of bleeding- monitor INR closely)
• Statins (e.g., simvastatin) (may increase the risk of statin toxicity and rhabdomyolysis)
• Other antibiotics (e.g., rifampin) (may affect clarithromycin efficacy)
• QT-prolonging drugs (e.g., certain antipsychotics) (may increase the risk of arrhythmias)
• Theophylline (may increase theophylline levels and risk of toxicity)
• Digoxin (may increase digoxin levels and risk of toxicity)
• Antacids (e.g., magnesium or aluminum hydroxide) (may decrease absorption- take clarithromycin separately)
• Antidiabetic medications (e.g., metformin) (no significant interaction but monitor for unusual blood glucose levels)

• The food interactions that should be considered while using Clarithromycin are:

• Avoid alcohol as it can increase the risk of gastrointestinal irritation
• High-sodium foods may affect the effectiveness and balance of the medication
• High-sugar foods can potentially impact the medication’s action and overall effectiveness.

Clarithromycin is a type of antibiotic that is taken orally in the form of a tablet or liquid suspension, and it is typically prescribed for the treatment of various bacterial infections. When storing Clarithromycin 500mg, it is important to keep the medication in its original container, and to store it at room temperature, between 68°F and 77°F (20°C and 25°C). The medication should be kept away from heat, direct sunlight, and moisture, and out of the reach of children and pets. It is also important to check the expiration date on the medication and to dispose of any expired medication properly. If there are any specific storage instructions on the medication label, one should follow those instructions accordingly. It is recommended to consult the patient's instructions that come with the medication, as well as follow the instructions from your healthcare provider.