Kleenlac 120ml Syrup

Lactulose, a synthetic disaccharide, primarily acts as an osmotic laxative. It is not absorbed in the small intestine and reaches the colon unchanged, where it is fermented by the resident bacteria. This fermentation process results in the production of organic acids, primarily lactic acid and acetic acid, along with gases such as carbon dioxide and hydrogen. These organic acids and gases increase the osmotic pressure within the colon, causing water retention in the stool, which softens it and promotes bowel movements. Additionally, the acidic environment created by the fermentation of lactulose helps to reduce the pH in the colon, which inhibits the growth of ammonia-producing bacteria and promotes the growth of beneficial bacteria, contributing to its therapeutic effects.

Lactulose, Galactose Microparticles

Laxative

Suspension

The following are the uses of Lactulose, Galactose Microparticles Syrup/Suspension:

• Used for treating chronic constipation, particularly in the elderly and those with a history of bowel obstruction.
• Used for improving bowel function in patients with hepatic encephalopathy, a complication of liver disease.
• Used for softening stools and reducing straining in patients with hemorrhoids or post-operative pain.
• Used for clearing the bowel before certain medical procedures or surgeries.
• Used for preventing and treating constipation in patients with limited mobility or spinal cord injuries.
• Used for promoting regularity in children with chronic constipation.
• Used for drawing fluid into the large intestine to ease passage of stool.

In the case of an overdose of Lactulose or Galactose Microparticles Syrup/Suspension, the primary concern is gastrointestinal distress. Symptoms may include severe diarrhea, abdominal pain, bloating, and nausea. In severe cases, dehydration and electrolyte imbalances can occur. Treatment involves managing these symptoms, providing supportive care, and ensuring proper hydration until the excess sugar is eliminated from the body. It is important to seek medical advice if an overdose is suspected.

In the case of a missed dose of Lactulose, it is recommended to take the missed dose as soon as you remember, unless it is almost time for your next scheduled dose. If it is close to the time of your next dose, skip the missed dose and continue with your regular dosing schedule. For Galactose Microparticles Syrup/Suspension, if a dose is missed, take it as soon as possible, but if it is near the time for your next dose, skip the missed dose and continue with your regular dosing regimen.

To administer the Lactulose, Galactose Microparticles Syrup/Suspension, gently shake the bottle, measure the prescribed dose with an oral syringe, and administer it orally, following the dosage instructions provided by your healthcare professional, which may vary based on individual needs.

Here are the conditions and situations when Lactulose, Galactose Microparticles Syrup/Suspension should not be used:

• Not suitable for individuals with galactosemia, a rare genetic disorder affecting galactose metabolism.
• Contraindicated in patients with a known allergy or hypersensitivity to lactulose or any of its excipients.
• Should not be used in patients with severe gastrointestinal conditions like intestinal obstruction, perforation, or acute abdomen.
• Not recommended for individuals with severe dehydration, unless proper rehydration measures are taken.
• Avoid use in patients with a history of severe gastrointestinal reactions to other laxatives.
• Not suitable for infants with low birth weight or premature babies, as it may affect their electrolyte balance.
• Should not be used in patients with fructose intolerance.

The side effects of Lactulose, Galactose Microparticles Syrup/Suspension may include:

• Diarrhea
• Nausea and vomiting
• Stomach cramps or pain
• Bloating and gas
• Dizziness
• Headache
• Fatigue and weakness
• Electrolyte imbalances (low potassium levels)

Following are the precautions and warnings for Lactulose, Galactose Microparticles Syrup/Suspension:

• Not suitable for patients with galactosemia, a rare genetic disorder affecting galactose metabolism.
• Caution is advised for patients with diabetes as it contains sugar and may affect blood glucose levels.
• May cause dehydration due to its laxative effect; ensure adequate fluid intake to prevent this.
• Prolonged use may lead to electrolyte imbalances, especially in elderly patients, requiring monitoring.
• Not recommended for long-term use without medical supervision.
• Patients with existing gastrointestinal conditions should use with caution and under medical advice.
• Discontinue use and consult a doctor if abdominal pain, nausea, or vomiting occurs.

Following are the drug interactions for Lactulose, Galactose Microparticles Syrup/Suspension:

• May reduce the effectiveness of antibiotics by altering gut flora, potentially requiring dosage adjustments.
• Can have additive effects when combined with other osmotic laxatives, increasing the risk of dehydration and electrolyte imbalances.
• Should be taken at least 2 hours apart from other oral medications to prevent interference with absorption.
• May cause fluctuations in blood glucose levels, requiring careful monitoring.
• Central nervous system depressants, Can potentially enhance the effects of sedatives and hypnotics.
• Probiotics, The use of probiotics may enhance the effectiveness of lactulose in certain conditions.
• Anticonvulsants, Lactulose may affect the absorption of anticonvulsant medications, requiring monitoring.
• Drugs affecting gut motility, Can interact with medications that affect gastrointestinal motility, potentially altering the desired effects.

Following are the food interactions for Lactulose, Galactose Microparticles Syrup/Suspension:

• Consuming large amounts of dairy products like milk or yogurt may lead to increased bowel movements due to the lactose content, potentially affecting the treatment's efficacy.
• High-fiber foods like whole grains, legumes, and certain vegetables might slow down the absorption of the medication.
• Fructose-rich foods such as fruits, honey, and some sweeteners may influence the absorption and effectiveness of the medication.
• Probiotic-rich foods like kefir, sauerkraut, and certain types of yogurt can potentially interact, as they may alter the gut microbiota.
• Sugary foods and beverages, including candy, sodas, and desserts, might influence the taste and effectiveness of the medication.
• Avoid excessive consumption of foods high in galactose, such as dairy and certain legumes, as this could potentially impact treatment.
• Foods with a high osmotic load, like salty snacks and processed foods, might affect the balance of fluids in the gut and impact the treatment.
• Alcohol should be consumed in moderation as it may influence the effectiveness of the medication and potentially cause dehydration.

Lactulose, Galactose Microparticles Syrup/Suspension should be stored in a controlled environment, preferably at room temperature (68°F to 77°F), with protection from excessive heat, moisture, and direct sunlight. Keep the bottle tightly sealed to maintain its integrity and prevent contamination. Ensure the medication is stored in a safe place, out of the reach of children and pets. When disposing of unused or expired syrup, do not pour it down the drain or dispose of it in regular household waste. Contact your pharmacist or healthcare provider for guidance on proper disposal methods to minimize environmental impact. Always adhere to local regulations and guidelines for medication disposal.

Following are the quick tips for Lactulose, Galactose Microparticles Syrup/Suspension:

• Consult your healthcare provider for the prescribed dosage of the syrup.
• Before each use, shake the bottle vigorously to ensure a uniform mixture.
• Administer the syrup with a glass of water, avoiding tea, coffee, or dairy products for better absorption.
• Maintain a consistent routine by taking your dose at the same time daily.
• To reduce the likelihood of stomach discomfort, consider taking the syrup with food or after meals.
• Store the syrup in a secure location, out of the reach of children.
• Ensure you finish the entire prescribed course of medication, even if you start feeling better.