KOFOUT SYP 120ML

Menthol acts as a cooling agent, providing a soothing sensation by activating TRPM8 receptors in the respiratory tract. Salbutamol, a beta-2 agonist, relaxes the smooth muscles in the airways by stimulating beta-2 adrenergic receptors, leading to bronchodilation. Bromhexine is an expectorant that reduces the viscosity of mucus, enhancing its clearance by inhibiting the synthesis of new mucus and stimulating the release of surfactant. Guaifenesin, another expectorant, increases respiratory tract fluid, thinning bronchial secretions and facilitating their removal through coughing.

Expectorant and bronchodilator

Suspension

The following are the uses of Menthol, Salbutamol, Bromhexine, Guaiphenesin Syrup/Suspension:

• Used for temporary relief of minor throat and mouth irritation, and coughs associated with a cold.
• Used to prevent and treat wheezing, shortness of breath, and troubled breathing caused by asthma, chronic bronchitis, emphysema, and other lung diseases.
• Used to relieve chest congestion, making it easier to cough up mucus.
• Used to thin and loosen mucus in the airways, making it easier to breathe and clear the airways.
• Used to treat symptoms of a stuffy nose, including sinus congestion and pressure.
• Used to temporarily relieve minor aches and pains of muscles and joints associated with the common cold.
• Used to provide a cooling sensation and act as a local anesthetic to relieve minor pain and itching.

In the case of an overdose of Menthol, Salbutamol, Bromhexine, and Guaiphenesin Syrup/Suspension, the severity of symptoms can vary. Excessive menthol may cause skin irritation and respiratory distress. Salbutamol overdose can lead to rapid heart rate and tremors. Bromhexine and Guaiphenesin overdoses may result in nausea, vomiting, and gastrointestinal discomfort. Prompt medical attention is necessary, and treatment should be guided by a healthcare professional to manage symptoms effectively.

In the case of a missed dose of Menthol, Salbutamol, Bromhexine, or Guaiphenesin Syrup/Suspension, it is generally recommended to take the medication as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one, as this may increase the risk of side effects. It is important to maintain a consistent dosing routine, but if you frequently miss doses, consult your healthcare provider for advice on how to manage your medication effectively.

To administer the Menthol, Salbutamol, Bromhexine, and Guaiphenesin Syrup/Suspension, shake the bottle well, measure the prescribed dose with an accurate measuring device, and take it orally as directed by your healthcare provider, typically with or without food, following the dosage instructions for your specific age group.

Here are the conditions or situations when Menthol, Salbutamol, Bromhexine, Guaiphenesin Syrup/Suspension should not be used:

• Not suitable for individuals with a known allergy or hypersensitivity to any of the active ingredients (Menthol, Salbutamol, Bromhexine, Guaifenesin) or excipients in the syrup/suspension.
• Contraindicated in patients with a history of severe cardiovascular diseases, including cardiac arrhythmias or recent myocardial infarction.
• Should not be used in patients with narrow-angle glaucoma.
• Not recommended for individuals with a history of seizures or epilepsy.
• Avoid using in patients with hyperthyroidism or an overactive thyroid gland.
• Not suitable for patients with known severe kidney or liver impairment.
• Should not be used in patients with a history of peptic ulcer disease or gastrointestinal bleeding.
• Contraindicated during breastfeeding, as the active ingredients may pass into breast milk.
• Not recommended for children below 2 years of age due to potential risks and lack of established safety and efficacy.

The side effects of Menthol, Salbutamol, Bromhexine, and Guaiphenesin Syrup/Suspension may include:

• Nausea and vomiting
• Stomach pain or cramps
• Diarrhea
• Dizziness or lightheadedness
• Increased heart rate or palpitations
• Nervousness or restlessness
• Dry mouth
• Skin rash or itching

Following are the precautions and warnings for Menthol, Salbutamol, Bromhexine, Guaiphenesin Syrup/Suspension:

• This medication should not be used in patients with known allergies or hypersensitivity to any of its components, including Menthol, Salbutamol, Bromhexine, or Guaiphenesin.
• Patients with a history of respiratory diseases, heart conditions, high blood pressure, diabetes, or thyroid problems should use this medication with caution and under medical supervision.
• It may cause dizziness or drowsiness; patients are advised to avoid driving or operating heavy machinery until they know how this medication affects them.
• Alcohol consumption should be avoided as it may worsen side effects.
• Not recommended for use in children under 12 years of age without medical advice.
• Pregnant and breastfeeding women should consult a healthcare professional before using this syrup.
• If symptoms persist or worsen, or if you experience rapid or irregular heartbeat, chest pain, severe dizziness, or difficulty breathing, discontinue use and seek medical attention immediately.
• Store this medication out of reach of children and at room temperature, away from direct sunlight and moisture.

Following are the drug interactions for Menthol, Salbutamol, Bromhexine, and Guaiphenesin Syrup/Suspension:

• Menthol may interact with other medications applied to the skin, increasing absorption and potential side effects.
• Salbutamol can interact with beta-blockers, reducing its effectiveness. It may also interact with certain antidepressants and other medications that affect the cardiovascular system.
• Bromhexine can increase the effects of other cough suppressants and may interact with certain antibiotics, affecting their absorption.
• Guaiphenesin may interact with medications that affect the central nervous system, such as sedatives and muscle relaxants, enhancing their effects.
• It may also increase the risk of bleeding when taken with anticoagulants.
• Menthol and Guaiphenesin combination may increase the risk of side effects when taken with other medications that have similar effects, such as other expectorants or cough suppressants.
• Concomitant use of this medication with other respiratory medications should be monitored for potential additive effects.

Following are the food interactions for Menthol, Salbutamol, Bromhexine, Guaiphenesin Syrup/Suspension:

• Citrus fruits and juices, particularly grapefruit, should be used with caution as they may alter the effectiveness of the medication, especially with Salbutamol, due to changes in liver enzyme activity.
• Caffeine intake should be monitored as it may interact with Guaiphenesin, potentially increasing side effects like nervousness, rapid heartbeat, and insomnia.
• Avoid excessive consumption of dairy products, as they can increase mucus production and reduce the effectiveness of Bromhexine.
• Spicy foods might be beneficial as they can help thin the mucus and aid in expectoration, but be cautious if you have a sensitive stomach.
• Alcohol should be avoided as it can increase the risk of side effects, especially with Salbutamol, and may interfere with the medication's effectiveness.
• A balanced diet rich in fluids, vitamins, and antioxidants can support the respiratory system and overall health during treatment.
• There is no specific food restriction for Menthol, but it's best to follow a healthy diet to ensure the medication's effectiveness.
• Always consult your healthcare provider for personalized advice and any specific dietary considerations.

Menthol, Salbutamol, Bromhexine, and Guaiphenesin Syrup/Suspension should be stored in a controlled environment, maintaining a cool and dry atmosphere at room temperature, shielded from direct sunlight and moisture. The medication should be securely sealed within its original packaging to maintain its integrity and prevent contamination. Avoid bathroom storage or proximity to heat sources like stoves, as temperature fluctuations can compromise the medicine's efficacy. Always adhere to proper disposal practices for any unused or expired syrup; refrain from flushing it down the toilet or drains. Consult your pharmacist or healthcare professional for safe disposal guidelines. Additionally, ensure the medication is stored securely away from children to prevent accidental ingestion.

Following are the quick tips for Menthol, Salbutamol, Bromhexine, Guaiphenesin Syrup/Suspension:

• Consult a doctor for proper prescription and dosage instructions.
• Shake the bottle vigorously to ensure a uniform mixture before each use.
• Administer the syrup with water; avoid tea, coffee, or dairy for better absorption.
• Maintain a consistent dosing schedule to ensure steady levels in the body.
• To minimize stomach irritation, consider taking it with food or after meals.
• Store the syrup safely, away from children, to prevent accidental consumption.
• Do not share your medication with others, even if they have similar symptoms.
• Inform your doctor about any other medications you are taking to avoid potential interactions.