KOPAQ 350MG 50ML

Iohexol 350MG, a commonly used contrast agent, operates by temporarily altering the density of tissues and fluids within the body, thus enabling enhanced visualization during diagnostic imaging procedures. This mechanism is primarily attributed to its high iodine content. When administered, the iodine atoms in Iohexol effectively absorb and attenuate X-rays, leading to increased contrast on radiographic images. This contrast enhancement facilitates the clear delineation of anatomical structures, making it invaluable for medical imaging techniques such as computed tomography (CT) scans and angiography. The iodine in Iohexol does not interact with the body's tissues but simply modifies the way X-rays pass through the body, providing a clearer image for diagnostic purposes.

Iohexol 350MG

Contrast Agent

Injectable solution

The following are the uses of Iohexol 350MG Liquid:

• Used for diagnostic radiography, allowing visualization of blood vessels and tissues.
• Used for angiocardiography to assess heart and blood vessel conditions.
• Used for venography to examine veins and identify blood clots.
• Used for CT urography to visualize the urinary tract and detect abnormalities.
• Used for CT scanning to provide detailed images of internal organs and structures.
• Used for determining blood volume and flow in various medical conditions.

In the case of an overdose of Iohexol 350MG Liquid, prompt medical attention is required. The severity of symptoms may vary, but common effects include nausea, vomiting, and in severe cases, kidney damage. It is important to contact emergency services or seek medical help immediately if an overdose is suspected. Quick action can help mitigate potential health risks and ensure appropriate treatment is provided to manage the overdose effectively. This medication should always be used as directed by a healthcare professional.

In the case of a missed dose of Iohexol 350MG Liquid, it is important to consult your healthcare provider or pharmacist for specific instructions. Generally, if you realize you have missed a dose, take it as soon as you remember, unless it is close to the time for your next scheduled dose. Do not double the dose to make up for a missed one, as this may increase the risk of side effects. If you miss a dose and it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule.

To administer Iohexol 350MG Liquid, measure the prescribed dose using an oral syringe or dosing cup, and swallow it directly; do not mix it with other liquids or food, and follow the dosage instructions provided by your healthcare professional.

Following are the conditions or situations when Iohexol 350MG Liquid should not be used:

• Must not be administered if the patient has a known allergy or hypersensitivity to Iohexol or any other ingredients in the formulation.
• Contraindicated in patients with severe renal impairment or kidney failure, as the drug is primarily eliminated through the kidneys.
• Should not be used in patients with a history of severe anaphylactic reactions to any contrast media.
• Not recommended for patients with a history of laryngeal or bronchial spasms, as it may trigger respiratory distress.
• Avoid in patients with severe cardiovascular instability, as the contrast media may affect blood pressure and heart function.
• Do not use in patients with a history of thyroid disease, as Iohexol may interfere with thyroid function tests.
• Contraindicated in patients with a history of multiple myeloma or other plasma cell dyscrasias.
• Should not be used in patients with a history of sickle cell disease or sickle cell trait.

The side effects of Iohexol 350MG Liquid may include:

• Allergic reactions, such as itching, rash, or hives.
• Nausea and vomiting.
• Headache.
• Dizziness or lightheadedness.
• Mild skin flushing.
• Mild pain or discomfort at the injection site.
• Temporary metallic taste in the mouth.
• Rare cases of kidney damage, especially in patients with pre-existing kidney conditions.

Following are the precautions and warnings for Iohexol 350MG Liquid:

• Do not use if you are allergic to Iohexol or any similar contrast agents.
• This medication should be used with caution in patients with kidney disease, diabetes, multiple myeloma, or heart disease, as it may worsen these conditions.
• Iohexol can cause dehydration, especially in elderly patients, so ensure adequate fluid intake before and after the procedure.
• It may lead to temporary vision changes, dizziness, or headaches. Avoid driving or operating heavy machinery until these effects subside.
• Inform your doctor if you have a history of thyroid problems, as Iohexol may interfere with thyroid function tests.
• Pregnant and breastfeeding women should consult their doctor, as this medication may pose risks to the fetus or infant.
• Some patients may experience a delayed allergic reaction, so monitor for symptoms like itching, rash, or breathing difficulties after the procedure.
• Patients with asthma or a history of severe allergic reactions should be closely monitored, as Iohexol can trigger severe allergic responses.

Following are the drug interactions for Iohexol 350MG Liquid:

• Iohexol may decrease the effectiveness of antidiabetic medications, leading to altered blood sugar control. Regular monitoring of blood glucose levels is advised.
• It can interact with metformin, potentially increasing the risk of lactic acidosis, a serious condition.
• Antihypertensive drugs' effects can be reduced by Iohexol, resulting in elevated blood pressure.
• Iohexol may increase the risk of bleeding when used with anticoagulants or antiplatelet drugs, requiring close monitoring.
• The risk of kidney damage may be elevated when combining Iohexol with nephrotoxic medications.
• Drugs that decrease urine production, such as NSAIDs or diuretics, can increase the risk of adverse renal effects when used with Iohexol.
• Iohexol can enhance the effects of certain medications metabolized by the liver, potentially requiring dosage adjustments.

Following are the food interactions for Iohexol 350MG Liquid:

• It is generally recommended to fast for a certain period before the procedure, typically 4 to 6 hours, to ensure accurate diagnostic results and avoid nausea or vomiting during the test.
• Avoid caffeine-containing beverages like coffee, tea, and energy drinks, as they can interfere with the contrast agent's effects and may lead to increased anxiety or changes in heart rate.
• High-fat meals should be avoided before the procedure as they can delay gastric emptying and potentially affect the timing and quality of the imaging.
• Grapefruit juice should be avoided as it can alter the metabolism of medications and potentially impact the body's response to the contrast agent.
• Alcohol should be strictly avoided before the procedure as it can interfere with the contrast agent's metabolism and may lead to dehydration, affecting the overall test results.
• Avoid sugary foods and drinks, as they can influence the contrast agent's taste and may cause nausea or discomfort during the procedure.
• It is advisable to maintain a clear liquid diet, including water, clear broths, and certain sports drinks, as instructed by your healthcare provider, to ensure optimal hydration and minimize the risk of adverse reactions.

Iohexol 350MG Liquid should be stored in a secure and controlled environment, preferably in a designated storage area with restricted access. It should be kept in a cool, dry place, away from direct sunlight, heat, and moisture to maintain its stability. The liquid should be stored in its original container, tightly sealed, to prevent contamination and ensure its integrity. It is crucial not to freeze the liquid as it may affect its effectiveness. When disposing of Iohexol, it is essential to follow local regulations and guidelines for pharmaceutical waste disposal. Do not pour it down the drain or dispose of it with regular household waste. Contact your healthcare provider or pharmacist for guidance on proper disposal methods to ensure environmental safety. Keep this medication out of children's reach to prevent accidental ingestion.

Following are the quick tips for Iohexol 350MG Liquid:

• Consult your healthcare provider for the correct dosage and administration instructions.
• Ensure the liquid is well-mixed before each use by gently shaking the container.
• Administer the prescribed dose accurately using the provided measuring device.
• Do not mix the liquid with other medications unless instructed by your doctor.
• If you experience any allergic reactions or severe side effects, seek immediate medical attention.
• Store the liquid at room temperature, away from direct sunlight and moisture.
• Always check the expiration date before using, and discard any expired medication properly.
• Keep a record of your medication usage to inform your healthcare provider during follow-up visits.