Kovastin (10mg) 10 Tablets

Rosuvastatin Calcium 10mg Tablet works primarily by inhibiting an enzyme in the liver called HMG-CoA reductase. This enzyme plays a crucial role in the production of cholesterol in the body. By blocking its action, rosuvastatin significantly reduces the liver's ability to produce low-density lipoprotein (LDL) cholesterol, often referred to as 'bad' cholesterol. This reduction in LDL cholesterol production leads to a decrease in its levels in the blood. Additionally, the medication can slightly increase high-density lipoprotein (HDL) or 'good' cholesterol, further contributing to improved lipid profiles in individuals taking the medication.

Statin (HMG-CoA reductase inhibitor)

Tablet

The following are the uses of Rosuvastatin Calcium 10mg Tablet:

• Used for lowering high cholesterol levels, especially in those who have not been able to control it through diet and exercise alone.
• Used for reducing the risk of heart disease and stroke by managing cholesterol levels.
• Used to treat high cholesterol in individuals with a genetic predisposition, helping to prevent long-term cardiovascular issues.
• Used for managing cholesterol and triglyceride levels in patients with combined lipid disorders.
• Used to slow down the formation of fatty deposits in arteries, improving blood flow.
• Used for patients with a history of heart attack or chest pain to prevent future cardiovascular events.
• Used to support lifestyle changes, ensuring cholesterol levels remain under control.

In the case of an overdose of Rosuvastatin Calcium 10mg Tablets, individuals may experience an increased risk of liver problems, muscle pain, and kidney issues. The severity of symptoms can vary, but immediate medical intervention is necessary. Symptoms may include severe muscle pain, weakness, and dark-colored urine, indicating potential liver or kidney damage. Prompt medical care should be sought to address these concerns and prevent further complications. Timely treatment can help manage the adverse effects and ensure the patient's well-being.

In the case of a missed dose of Rosuvastatin Calcium 10mg Tablet, it is important to take the medication as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one, as this may increase the risk of side effects. If you frequently forget to take your medication, consider setting reminders or using a pill organizer to help you stay on track with your treatment plan. It is crucial to maintain consistency in taking your medication as prescribed.

To take Rosuvastatin Calcium 10mg Tablet, swallow the tablet whole with a full glass of water, preferably at the same time each day, either with or without food, as directed by your healthcare professional.

Following are the conditions when Rosuvastatin Calcium 10mg Tablet should not be taken:

• Avoid if you have a known allergy to Rosuvastatin or any other statin medications.
• Do not take if you are pregnant or breastfeeding, as it may harm the unborn baby.
• Contraindicated in individuals with active liver disease or persistent elevations in liver enzymes.
• Should not be used if you have a history of muscle pain, tenderness, or weakness, especially if caused by previous statin use.
• Not recommended for individuals with uncontrolled hypothyroidism.
• Avoid if you have or have had kidney problems or kidney failure.
• Do not take this medication if you have a condition where your body is unable to remove uric acid (hyperuricemia).

The side effects of Rosuvastatin Calcium 10mg Tablet may include:

• Muscle pain and weakness
• Joint pain
• Nausea and vomiting
• Constipation or diarrhea
• Abdominal pain
• Increased blood sugar levels
• Headache
• Increased liver enzymes (detected in blood tests)

Following are the precautions and warnings for Rosuvastatin Calcium 10mg Tablet:

• Patients with a known allergy to Rosuvastatin or any other statin medication should not take this medication.
• Regular liver function tests are required as Rosuvastatin can affect liver enzymes. Discontinue use if liver enzymes significantly increase.
• Those with a history of liver disease or excessive alcohol consumption should use with caution and under medical supervision.
• Patients with diabetes should monitor blood sugar levels regularly as Rosuvastatin may slightly increase blood sugar.
• May cause muscle pain or weakness; consult a doctor if symptoms occur, especially if accompanied by fever or dark-colored urine.
• Not recommended for pregnant women as it may harm the unborn baby. Effective birth control methods should be used.
• Breastfeeding women should avoid this medication as it may pass into breast milk and harm the nursing infant.

Following are the drug interactions for Rosuvastatin Calcium 10mg Tablet:

• Cyclosporine, a drug used in organ transplants, can increase the risk of myopathy and rhabdomyolysis when taken with Rosuvastatin.
• Concomitant use of fibrates, especially gemfibrozil, may increase the risk of rhabdomyolysis and renal failure.
• The effectiveness of oral contraceptives may be reduced when taken with Rosuvastatin.
• Rosuvastatin can increase the blood levels of warfarin, a blood thinner, potentially affecting INR and bleeding risk.
• When used with other statins or lipid-lowering doses of fibrates, there is an increased risk of myopathy and rhabdomyolysis.
• Antacids containing aluminum or magnesium can decrease the absorption of Rosuvastatin, so it should be taken at least 2 hours apart.
• The concentration of Rosuvastatin may be increased by certain medications like cytochrome P450 2C9 inhibitors (e.g., fluconazole).

Following are the food interactions for Rosuvastatin Calcium 10mg Tablet:

• Avoid consuming large amounts of grapefruit or grapefruit juice as it can increase the concentration of the medication in the blood, potentially leading to an increased risk of side effects.
• Limit alcohol consumption as it can increase the risk of liver-related issues when combined with this medication.
• Do not consume high-fat meals as they may decrease the absorption and effectiveness of the drug.
• Avoid high-sodium foods, as Rosuvastatin is often prescribed to manage cholesterol and reduce sodium intake.
• Consume foods rich in omega-3 fatty acids like fish and nuts, which can complement the medication's effects on heart health.
• Include fiber-rich foods like whole grains, legumes, and fruits to support overall cardiovascular health.
• Avoid or limit the intake of cholesterol-rich foods such as organ meats, egg yolks, and high-fat dairy products.
• Green tea and dark chocolate (in moderation) may have beneficial effects on cholesterol levels and overall cardiovascular health.

Rosuvastatin Calcium 10mg Tablets should be stored in a secure and dry location, preferably in a medicine cabinet or a designated storage area. Maintain a consistent room temperature, avoiding exposure to direct sunlight, excessive heat, or moisture as these conditions can degrade the medication. Always keep the tablets in their original packaging, ensuring the container is tightly sealed to maintain its integrity and prevent contamination. It is crucial to dispose of any unused or expired tablets responsibly; do not flush them down the toilet or discard them in regular household waste. Contact your pharmacist or healthcare provider for guidance on proper disposal methods in your area. Remember to keep all medications out of children's reach to prevent accidental consumption.

Following are the quick tips for Rosuvastatin Calcium 10mg Tablet:

• Always take the tablet as directed by your doctor, typically once daily.
• It can be taken with or without food, but taking it at the same time each day is essential.
• Swallow the tablet whole with a full glass of water; do not crush, chew, or break it.
• Avoid grapefruit juice and alcohol as they may interact with the medication.
• Inform your doctor about all medications you are taking to prevent potential drug interactions.
• Regularly monitor your liver function and blood sugar levels while on this medication.
• Store the tablets in a cool, dry place, away from direct sunlight and moisture.