KRIN SACHETS

Cranberry extract is believed to work primarily through its ability to prevent urinary tract infections (UTIs) by inhibiting the adhesion of harmful bacteria, particularly *Escherichia coli* (E. coli), to the walls of the urinary tract. The active compounds in cranberry, especially proanthocyanidins, are thought to block the bacteria from attaching to the urinary tract lining, thereby reducing the likelihood of infection. Additionally, cranberry extract has antioxidant properties, which may help to reduce inflammation and promote overall urinary tract health. While cranberry extract is often used as a preventive measure, it is not intended to treat active infections but may help in reducing recurrence.

Cranberry Extract

antioxidant

Sachet

The following are the uses of Cranberry Extract Sachet:

• Prevention of urinary tract infections (UTIs) by inhibiting the adherence of bacteria to the urinary tract walls.
• Support for overall urinary tract health and function.
• Prevention of kidney stones by reducing the formation of certain crystals in the urinary tract.
• Management of bladder and urinary tract discomfort.
• Antioxidant properties to support general immune system health.
• May help reduce the recurrence of UTIs in individuals with a history of recurrent infections.

Following are the doses of Cranberry Extract Sachet:

• The usual dose for adults is one sachet, typically taken once daily.
• For prevention of urinary tract infections, the dose may be adjusted as recommended by a healthcare provider.
• In cases of recurrent UTIs or as advised by a healthcare provider, the dose may be increased, but it is important to follow the exact instructions given by the healthcare provider.
• For children, the dosage should be determined by a healthcare provider based on age and condition.

In case of an overdose of Cranberry Extract Sachet, immediate medical attention should be sought. While cranberry extract is generally considered safe, excessive intake may lead to mild gastrointestinal symptoms such as diarrhea, stomach discomfort, or nausea. If an overdose occurs, it is recommended to stop taking the supplement and drink plenty of water to help flush out the excess. It is important not to induce vomiting or take any other actions without consulting a healthcare provider. If symptoms such as persistent stomach pain or unusual reactions occur, seek medical attention immediately. Always follow the prescribed dosage and usage instructions to avoid overdose.

If you miss a dose of Cranberry Extract Sachet, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take two doses at the same time to make up for the missed dose, as this may increase the risk of side effects or discomfort

To use Cranberry Extract Sachet, follow the instructions provided by your healthcare provider or as indicated on the product label. Typically, one sachet should be dissolved in water and consumed once or twice daily, depending on the recommendation. Stir the powder well to ensure it is fully dissolved. It can be taken with or without food, but it is important to follow the specific directions given by your healthcare provider. Consistency is key, so try to take it at the same time each day to maintain steady levels in your system.

Following are the situations when Cranberry Extract Sachet should not be used:

• Should not be used in individuals with a known allergy to cranberry or any of the components of the extract.
• Contraindicated in patients who have a history of kidney stones, as cranberry may increase the risk of stone formation.
• Not recommended for individuals on blood thinners (e.g., warfarin) without consulting a healthcare provider, as cranberry may interact with these medications.
• Should not be used in children under the age of 12 years without advice from a healthcare provider.
• Not recommended for individuals with a history of severe gastrointestinal issues unless advised by a healthcare provider.
• Should not be used as a substitute for medical treatment in the case of urinary tract infections (UTIs) or other conditions requiring prescribed antibiotics.

The side effects of Cranberry Extract Sachet may include:

• Upset stomach
• Diarrhea
• Increased urination
• Mild headache
• Allergic reactions (rare) such as rash or itching
• Kidney stone formation (in individuals predisposed)

Following are the precautions and warnings for Cranberry Extract Sachet:

• Should not be used in individuals with a known allergy to cranberry or any of the components in the extract.
• Caution is advised in patients with a history of kidney stones, as cranberry extract may increase the risk of forming certain types of stones due to its high oxalate content.
• Patients on blood thinners (e.g., warfarin) should consult a healthcare provider before using cranberry extract, as it may interfere with blood clotting and increase the risk of bleeding.
• Not recommended for individuals with a history of gastrointestinal issues such as acid reflux or ulcers, as cranberry can sometimes irritate the stomach.
• Caution is also advised in diabetic patients, as cranberry extract can sometimes influence blood sugar levels, especially when consumed in large amounts.
• Pregnant or breastfeeding women should consult their healthcare provider before using cranberry extract to ensure its safety.

Following are the drug interactions for Cranberry Extract Sachet:

• May interact with warfarin (a blood-thinning medication), increasing the risk of bleeding due to cranberry’s mild anticoagulant effects.
• High doses of cranberry may interfere with the metabolism of certain drugs through cytochrome P450 enzymes, potentially altering their effectiveness.
• Caution is advised when used with drugs that affect kidney function, as cranberry extract may exacerbate kidney stone formation in susceptible individuals.
• Should not be combined with medications known to lower blood pressure, as cranberry may have a mild diuretic effect, potentially leading to hypotension.
• Use cautiously with certain diabetic medications, as cranberry extract may influence blood sugar levels.

Following are the food interactions for Cranberry Extract Sachet:

• Grapefruit and grapefruit juice should be avoided, as they may interfere with the absorption and effectiveness of cranberry extract.
• Cranberry may enhance the effects of certain blood-thinning medications, so it should be used cautiously with foods high in vitamin K or other anticoagulant-rich foods (e.g., leafy greens, broccoli).
• High-sugar foods or beverages may increase the risk of urinary tract infections (UTIs), counteracting cranberry extract’s potential benefits in UTI prevention.
• Avoid excessive consumption of cranberry extract with alcohol, as it may increase the risk of kidney stones or interact with medications metabolized in the liver.

Cranberry Extract Sachet should be stored in a cool, dry place, away from direct sunlight and moisture to maintain its potency and effectiveness. Keep the sachets tightly sealed in their original packaging to protect them from air and humidity. Ensure the product is stored out of the reach of children and pets to prevent accidental ingestion. If the sachet has a “use by” or expiration date, make sure to use the product before that date to ensure its full effectiveness. For disposal, do not flush the sachets down the toilet or pour them into drains. If no specific disposal instructions are provided, dispose of them in household waste after sealing them in a bag or container to avoid exposure to others.

Take the cranberry extract sachets as directed by your healthcare provider for optimal results. •Dissolve the contents of the sachet in a glass of water or as instructed on the packaging. •Ensure you follow the recommended dosage to avoid potential side effects or complications. •For best results, incorporate the sachets as part of a balanced diet and healthy lifestyle. •Keep the sachets in a cool, dry place and ensure they are securely sealed to maintain their efficacy

Cranberry Extract Sachet does not typically require routine laboratory screening or monitoring. However, in certain cases where there are concerns related to the individual's health or underlying conditions, the following may be considered:

• Regular consultations with a healthcare provider to monitor the effectiveness of the treatment, particularly if used for urinary tract health or other specific concerns.
• If you experience any unusual side effects, such as gastrointestinal discomfort, consult your healthcare provider for further evaluation.
• Patients with a history of kidney problems or those taking other medications should check with their healthcare provider regularly to ensure safe use of cranberry extract.