LAC CALCIUM CITRATE MALATE 120S

Calcium Citrate Malate is a calcium supplement that is formulated to enhance calcium absorption in the body. The mechanism of action involves the breakdown of calcium citrate malate into its constituent ions, including calcium, citrate, and malate, in the digestive tract. Citrate and malate ions play a crucial role in facilitating calcium absorption by forming soluble complexes with calcium ions. These complexes are more easily absorbed through the intestinal wall, allowing for enhanced calcium uptake into the bloodstream. The increased calcium absorption is particularly beneficial for individuals with calcium deficiencies or conditions requiring higher calcium intake, as it helps maintain proper bone mineralization, supports muscle function, and contributes to overall calcium homeostasis.

CALCIUM CITRATE MALATE

Calcium salt.

Tablet

The following are the uses of CALCIUM CITRATE MALATE Tablet:

• Used for preventing and treating calcium deficiencies, especially in conditions like osteoporosis and rickets.
• Used for promoting bone health and strength, aiding in the development and maintenance of a strong skeletal structure.
• Used for supporting muscle function and nerve signaling, ensuring proper muscle contractions and nerve communication.
• Used for alleviating heartburn and indigestion, as it can neutralize excess stomach acid.
• Used for enhancing the absorption of other nutrients, particularly in individuals with digestive issues.
• Used for maintaining dental health, as it contributes to strong teeth and may help prevent tooth decay.
• Used for supporting overall enzyme function and metabolic processes in the body.
• Used for aiding in blood clotting mechanisms, ensuring proper wound healing.

In the case of an overdose of Calcium Citrate Malate Tablets, the primary concern is the potential for hypercalcemia, which can lead to symptoms such as nausea, vomiting, constipation, and in severe cases, kidney damage. Prompt medical attention is necessary to manage symptoms and prevent complications. Treatment may include gastric lavage, fluid and electrolyte balance, and monitoring of calcium levels to ensure a safe recovery from the overdose. It is crucial to seek medical advice for specific treatment options.

In the case of a missed dose of CALCIUM CITRATE MALATE Tablet, it is generally advised to take the missed dose as soon as you remember. However, if it's almost time for your next scheduled dose, it's best to skip the missed dose and continue with your regular dosing schedule. Avoid taking a double dose to make up for a missed one, as this may increase the risk of side effects. If you miss several doses or have concerns, it's recommended to consult your healthcare provider for further guidance on how to manage missed doses and ensure you're receiving the appropriate calcium supplementation.

To take Calcium Citrate Malate Tablet, swallow the tablet whole with a full glass of water, preferably with a meal or snack, as directed by your healthcare provider, typically once or twice daily, to enhance calcium absorption and support bone health.

Following are the circumstances when CALCIUM CITRATE MALATE Tablet should not be taken:

• Not suitable for individuals with a known allergy or hypersensitivity to calcium citrate malate or any of its excipients.
• Contraindicated in patients with severe hypercalcemia (high blood calcium levels) or conditions that lead to excessive calcium levels.
• Should not be used in patients with kidney stones or a history of kidney disease, as it may increase the risk of stone formation.
• Not recommended for individuals with hyperparathyroidism, as it can worsen calcium metabolism.
• Avoid in patients with sarcoidosis, as it may lead to excessive calcium levels.
• Contraindicated in patients with conditions causing hypercalciuria (high calcium levels in urine), such as renal tubular acidosis.
• Should not be used in individuals with a history of kidney failure or severe kidney impairment.

The side effects of CALCIUM CITRATE MALATE Tablet may include:

• Constipation
• Nausea and vomiting
• Stomach pain or upset
• Dry mouth
• Increased thirst
• Frequent urination
• Muscle or bone pain
• Fatigue

Following are the precautions and warnings for CALCIUM CITRATE MALATE Tablet:

• Individuals with a known allergy to calcium citrate malate or any of its ingredients should not use this medication.
• Patients with a history of kidney stones or kidney disease should exercise caution and consult a healthcare professional before use, as calcium supplementation may need to be monitored in these cases.
• This medication may cause constipation, so ensure you drink plenty of fluids and maintain a fiber-rich diet to prevent this side effect.
• Patients with a history of gastrointestinal disorders should be monitored for potential exacerbation of symptoms.
• Calcium supplementation may interact with certain medications; consult your doctor if you are taking other medications regularly.
• Do not exceed the recommended dosage, as excessive calcium intake can lead to serious health issues.
• Consult a healthcare professional if you are pregnant, breastfeeding, or planning to become pregnant, as calcium requirements may vary during these periods.
• If you have any underlying medical conditions or are taking other supplements, inform your doctor to ensure safe and effective use.

Following are the drug interactions for CALCIUM CITRATE MALATE Tablet:

• Thiazide diuretics like hydrochlorothiazide can decrease the excretion of calcium, leading to potential hypercalcemia.
• Bisphosphonates, such as alendronate, may have reduced absorption when taken with calcium supplements. Separate doses by at least 2 hours.
• Calcium can decrease the absorption of tetracycline antibiotics, such as doxycycline. Take calcium supplements at least 2 hours apart.
• Calcium supplements may reduce the effectiveness of levothyroxine, a thyroid medication. Separate doses by several hours.
• Antibiotics like ciprofloxacin and norfloxacin may bind with calcium, reducing their absorption. Avoid taking them together.
• Corticosteroids, such as prednisone, can increase calcium excretion, and long-term use may lead to osteoporosis.
• Calcium can decrease the absorption of phenytoin, an anticonvulsant, potentially affecting its effectiveness.
• Proton pump inhibitors (PPIs) like omeprazole may increase calcium absorption, and long-term use of PPIs may impact bone health.

Following are the food interactions to consider with CALCIUM CITRATE MALATE Tablet:

• Consuming calcium-rich foods like dairy products (milk, cheese, yogurt), leafy green vegetables, and calcium-fortified foods can enhance the absorption of calcium from the tablet.
• Vitamin D-rich foods such as fatty fish, egg yolks, and fortified dairy products can improve calcium absorption, as Vitamin D aids in calcium metabolism.
• Avoid excessive intake of high-oxalate foods like spinach, rhubarb, and sweet potatoes, as oxalates can bind with calcium and reduce its absorption.
• Caffeine-containing beverages like coffee and tea may interfere with calcium absorption, so it's advisable to limit their consumption around the time of taking the tablet.
• Ensure a balanced diet with adequate protein, as protein-rich foods can enhance calcium absorption in the body.
• Avoid high-fiber foods or fiber supplements at the same time as taking the tablet, as fiber can potentially reduce mineral absorption.
• Maintaining a healthy, varied diet that includes fruits, vegetables, whole grains, and lean proteins supports overall calcium absorption and bone health.

Calcium Citrate Malate Tablets should be stored in a cool and dry environment, preferably in their original container, away from direct sunlight and moisture. It is crucial to maintain a stable temperature, avoiding exposure to heat sources like radiators or stoves, as extreme temperatures can impact the medication's quality. Always check the expiration date, and if the tablets have passed their expiry, dispose of them responsibly. Do not dispose of them via household waste or down the drain; instead, follow local guidelines or consult your pharmacist for safe disposal methods. Keep the medication away from children to prevent accidental consumption.

Following are the quick tips for Calcium Citrate Malate Tablet:

• Consult your healthcare provider for the right dosage and duration tailored to your needs.
• Swallow the tablet whole with a glass of water, avoiding crushing or chewing for best results.
• Maintain a consistent schedule by taking the tablet at the same time each day.
• Ensure you complete the full course as prescribed, even if you feel better before finishing.
• If you forget a dose, take it as soon as you remember, but avoid doubling up to catch up.
• Store the tablets in a cool, dry place, away from direct sunlight and moisture.
• Keep the medication out of children's reach to prevent accidental consumption.