Lamnet (100mg) 30 Tablets

Lamivudine 100mg Tablet, a nucleoside reverse transcriptase inhibitor (NRTI), acts by interfering with viral replication in the treatment of HIV and chronic hepatitis B. It selectively inhibits the HIV reverse transcriptase enzyme, preventing the conversion of viral RNA into DNA. Lamivudine is phosphorylated within cells to its active form, which competes with the natural substrate deoxycytidine triphosphate for incorporation into nascent viral DNA chains, resulting in chain termination and inhibition of viral replication. This mechanism effectively reduces the amount of HIV in the body, helping to control the infection and allowing for improved immune function.

Lamivudine 100mg

Nucleoside reverse transcriptase inhibitor (NRTI)

Tablet

The following are the uses of Lamivudine 100mg Tablet:

• Used for treating HIV (Human Immunodeficiency Virus) infection in combination with other anti-HIV medicines.
• Used to suppress the virus and help improve immune function.
• Used in managing chronic Hepatitis B infections, reducing viral load and improving liver health.
• Used for reducing the risk of HIV transmission when taken consistently by individuals with HIV.
• Used to prevent mother-to-child transmission of HIV during pregnancy and childbirth.
• Used for long-term management, helping to maintain viral suppression and prevent disease progression.
• Used in specific treatment regimens tailored to an individual's viral resistance and overall health.

To be taken as per doctor's prescription

In the case of an overdose of Lamivudine 100mg Tablets, it is important to recognize the potential symptoms and take appropriate action. Overdosing on this medication may lead to an increased risk of adverse effects, including gastrointestinal issues, headaches, and, in severe cases, liver problems. If you suspect an overdose, seek medical advice promptly. Contact a healthcare professional or poison control center for guidance on managing the situation effectively and ensuring the patient's well-being.

In the case of a missed dose of Lamivudine 100mg Tablet, it is important to take the medication as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one. However, if you frequently miss doses, it is best to consult your healthcare provider for advice, as they may recommend a different approach to ensure the medication's effectiveness.

To take Lamivudine 100mg Tablet, swallow the tablet whole with a full glass of water, preferably at the same time each day, following the dosage instructions provided by your healthcare professional, typically once or twice daily as part of a combination therapy for HIV or chronic hepatitis B treatment.

Following are the conditions/situations when Lamivudine 100mg Tablet should not be taken:

• Should not be taken by individuals with a known hypersensitivity or allergy to Lamivudine or any of its excipients.
• Not recommended for patients with severe kidney impairment without adjusting the dosage.
• Contraindicated in patients with liver disease, including those with elevated liver enzymes.
• Should be used with caution in patients with a history of pancreatitis, and should be discontinued if pancreatitis develops.
• Not suitable for individuals with a rare hereditary problem of galactose intolerance, severe lactase deficiency, or glucose-galactose malabsorption.
• Should not be taken by patients who are also receiving other medications containing Lamivudine to avoid double dosing.

The side effects of Lamivudine 100mg Tablet may include:

• Nausea and vomiting
• Fatigue and weakness
• Headache
• Diarrhea
• Dizziness
• Insomnia
• Skin rash or itching
• Respiratory issues like shortness of breath

Following are the precautions and warnings for Lamivudine 100mg Tablet:

• This medication is not recommended for patients with a history of severe hypersensitivity or allergic reactions to Lamivudine or any of its components.
• Patients with kidney problems should exercise caution and consult a healthcare professional, as dosage adjustments might be necessary.
• Lamivudine may cause lactic acidosis, a serious medical condition, and should be used with caution in patients at risk, including those with liver disease or obesity.
• Regular monitoring of liver function is recommended, especially for patients with pre-existing liver conditions.
• It is important to continue taking Lamivudine as prescribed, even if you feel well, to ensure the effectiveness of the treatment.
• If you are undergoing HIV treatment, do not stop taking Lamivudine without consulting your healthcare provider to prevent the risk of HIV resistance.
• Pregnant or breastfeeding women should consult their doctor before taking Lamivudine, as it may pass into breast milk and affect the baby.

Following are the drug interactions for Lamivudine 100mg Tablet:

• Co-administration with other nucleoside reverse transcriptase inhibitors (NRTIs) like zidovudine may increase the risk of hematologic toxicity.
• Lamivudine can interact with doxorubicin, potentially increasing its concentration and risk of adverse effects.
• Rifampin may decrease the effectiveness of Lamivudine by inducing its metabolism.
• Probenecid can increase the plasma concentration of Lamivudine by inhibiting renal secretion.
• The risk of pancreatitis may be elevated when combined with didanosine.
• Lamivudine may reduce the therapeutic effect of trimethoprim/sulfamethoxazole when used together.
• When taken with interferon alfa, there may be an increased risk of hepatotoxicity.

Following are the food interactions for Lamivudine 100mg Tablet:

• Lamivudine can be taken with or without food, but maintaining a consistent routine is recommended for optimal absorption.
• Grapefruit and grapefruit juice should be avoided as they may interfere with the metabolism of Lamivudine, potentially leading to increased drug levels and a higher risk of side effects.
• Alcohol consumption should be limited as it may increase the risk of liver-related adverse effects, especially in individuals with underlying liver conditions.
• Avoid high-fat meals as they may decrease the absorption of Lamivudine, affecting its effectiveness.
• Avoid caffeine or limit its intake as it may interact with Lamivudine, potentially causing increased side effects such as nervousness and insomnia.
• Patients should stay well-hydrated and maintain a balanced diet to support overall health and medication effectiveness.
• Consult your healthcare provider for personalized dietary recommendations and any specific food restrictions related to your medical condition.
• Avoid consuming herbal supplements or alternative medicines without medical advice, as they may interact with Lamivudine.

Lamivudine 100mg Tablets should be stored in a cool, dry place, preferably at room temperature, away from excessive heat and moisture. Keep the tablets in their original container, tightly sealed, to maintain their integrity and protect them from light and humidity. It is crucial to adhere to the storage instructions to ensure the medication's effectiveness. Dispose of any unused or expired tablets responsibly; do not flush them down the toilet or discard them into the environment. Consult your pharmacist or local waste management guidelines for appropriate disposal methods. Keep the medication away from children and pets to prevent accidental consumption.

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Following are the quick tips for Lamivudine 100mg Tablet:

• Adhere to the prescribed dosage and treatment duration as advised by your doctor.
• Take the tablet at the same time each day to maintain consistent medication levels.
• Swallow the tablet whole with a full glass of water; do not crush, chew, or break it.
• Lamivudine can be taken with or without food, but taking it with food may reduce stomach upset.
• Avoid missing doses; if you miss a dose, take it as soon as you remember, unless it's almost time for the next dose.
• Inform your doctor about all medications you are taking to prevent potential drug interactions.
• Store the tablets at room temperature, away from moisture and light, and out of reach of children.