Lancerid (30mg) 1 Vial Injection/Infusion

Lansoprazole 30mg injection works by inhibiting the gastric H+/K+-ATPase (proton pump) of the parietal cells, which is the final step of gastric acid secretion. This medication binds covalently to two cysteine residues in the gastric proton pump of the parietal cells, thereby inhibiting acid secretion. By suppressing gastric acid secretion, lansoprazole helps reduce gastric acidity and increase the pH of the stomach, which can aid in the healing of gastric and duodenal ulcers and provide relief from acid-related conditions.

Lansoprazole 30mg

Proton pump inhibitor.

injection

The following are the uses of Lansoprazole 30mg injection:

• Used for treating severe acid reflux and healing stomach ulcers
• Used to manage gastroesophageal reflux disease (GERD)
• Used to reduce stomach acid production
• Used to relieve heartburn and difficulty swallowing
• Used for long-term treatment of Zollinger-Ellison syndrome
• Used for preventing and treating stomach ulcers caused by NSAIDs
• Used for improving digestion and reducing acid-related discomfort
• Used to promote healing of the esophagus in severe cases of acid damage

In the case of an overdose of Lansoprazole 30mg injection, it is important to recognize the potential severity of the situation. Symptoms may include dizziness, headache, and blurred vision. Promptly seek medical advice and inform healthcare professionals about the overdose. They will provide guidance on the necessary steps, which could include monitoring vital signs and providing supportive care to manage any adverse effects. Timely intervention is crucial to ensure the best possible outcome.

In the case of a missed dose of Lansoprazole 30mg injection, it is important to administer the medication as soon as you remember. If it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one. If you miss multiple doses, contact your healthcare provider for guidance, as they may advise you to restart the medication or provide alternative instructions to ensure the treatment remains effective.

To administer Lansoprazole 30mg injection, insert the needle into the vial, withdraw the prescribed dose, and inject it slowly into the vein over 2-3 minutes, ensuring the needle is in the correct position to prevent extravasation.

Following are the conditions when Lansoprazole 30mg injection should not be administered:

• Should not be used in individuals with a known allergy to Lansoprazole or other proton pump inhibitors (PPIs).
• Contraindicated in patients with severe liver impairment or liver disease.
• Not recommended for individuals with low magnesium levels or conditions causing low magnesium levels.
• Should not be used if there is a history of hypersensitivity or severe reactions to any components in the injection.
• Contraindicated in patients with a rare metabolic disorder called phenylketonuria, as some Lansoprazole injections may contain phenylalanine.
• Not suitable for individuals with a history of serious skin reactions to PPIs.

The side effects of Lansoprazole 30mg injection may include:

• Diarrhea
• Abdominal pain
• Nausea and vomiting
• Headache
• Dizziness
• Skin rash or itching
• Fatigue and weakness
• Increased liver enzymes

Following are the precautions and warnings for Lansoprazole 30mg injection:

• This medication should not be used in patients with known hypersensitivity or severe allergic reactions to Lansoprazole or other proton pump inhibitors.
• Lansoprazole should be used with caution in patients with liver problems, as it is primarily metabolized by the liver. Regular monitoring is necessary.
• Prolonged use of Lansoprazole may increase the risk of gastrointestinal infections and osteoporosis. Long-term use should be accompanied by appropriate monitoring.
• Patients with vitamin B12 deficiency or those at risk should be monitored as Lansoprazole may reduce its absorption.
• It may interact with other medications; patients should inform their doctor about all medications they are taking.
• Lansoprazole may mask symptoms of stomach cancer. Proper investigation should be done before starting treatment.
• This medication is not recommended for children and adolescents, as its safety and efficacy have not been established in this age group.
• Lansoprazole may cause dizziness and blurred vision; patients should not drive or operate heavy machinery until they know how this medication affects them.

Following are the drug interactions for Lansoprazole 30mg injection:

• Concomitant use with Clopidogrel may reduce the effectiveness of Clopidogrel, potentially affecting blood clotting.
• Lansoprazole can decrease the absorption of drugs that require acidic pH for absorption, such as Ketoconazole and iron salts.
• It may increase blood levels of certain medications like Diazepam and Phenytoin, leading to potential side effects.
• Lansoprazole can reduce the metabolism of drugs metabolized by the liver enzyme CYP1A2, including Caffeine and Theophylline, increasing their concentrations.
• The effect of anticoagulants like Warfarin may be altered, requiring close monitoring of INR values.
• Drugs that rely on gastric acid for activation, such as Ampicillin esters, may have reduced effectiveness.
• Lansoprazole may increase plasma concentrations of Sucralfate, potentially requiring dosage adjustments.

Following are the food interactions to be aware of with Lansoprazole 30mg injection:

• Avoid consuming alcohol during treatment as it can reduce the effectiveness of Lansoprazole and increase the risk of liver-related side effects.
• Grapefruit and grapefruit juice should be avoided as they can increase the concentration of Lansoprazole in the body, potentially leading to an increased risk of side effects.
• High-fat meals can delay the absorption of Lansoprazole, potentially reducing its effectiveness. It is best to take the medication 30 minutes before a meal.
• Caffeine-rich foods and beverages like coffee, tea, and chocolate may increase stomach acid production and reduce the efficacy of Lansoprazole. Consider reducing caffeine intake.
• Spicy foods can irritate the stomach lining and potentially worsen symptoms, especially in individuals with acid reflux or gastritis. It's advisable to limit spicy food consumption.
• Avoid smoking as it can decrease the effectiveness of Lansoprazole and slow down the healing process of stomach ulcers.
• Dairy products, especially milk, may interact with Lansoprazole and reduce its absorption. It is recommended to separate milk consumption from Lansoprazole dosing by at least 2 hours.
• Some protein-rich foods like red meat and eggs may stimulate stomach acid secretion, potentially reducing the medication's effectiveness. Consider a balanced diet with moderate protein intake.

Lansoprazole 30mg injection should be stored in a controlled environment, preferably between 68°F and 77°F (20°C and 25°C), with brief excursions permitted between 59°F and 86°F (15°C and 30°C). Protect the injection from excessive heat, direct sunlight, and moisture by keeping it in its original packaging until use. Do not freeze the medication as it may affect its potency. Once opened, use the injection promptly and discard any unused portion. For disposal, do not pour it down the drain or flush it into the toilet. Contact your healthcare provider or pharmacist for guidance on proper disposal methods to ensure environmental safety. Keep this medication out of children's reach to prevent accidental exposure.

Following are the quick tips for Lansoprazole 30mg injection:

• Administer the injection under medical supervision for best results.
• Ensure the injection is prepared and stored as per the instructions.
• Lansoprazole injection should be administered by a healthcare professional.
• Inform your doctor if you have any allergies or medical conditions before injection.
• Avoid missing doses; take the injection at the same time each day to maintain effectiveness.
• Do not reuse needles or syringes; dispose of them safely after use.
• Report any side effects or unusual symptoms to your doctor promptly.
• Store the injection as directed on the package or by your pharmacist.