LARIMEF 250MG TAB 6'S

LARIMEF 250MG TAB 6'S

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  • Manufacturer IMPORTED
  • Generic Name MEFLOQUIN

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Product Information

  • Description
  • Ingredients
  • Drug Class
  • Dosage Form
  • Uses
  • In case of Overdose
  • Missed Dose
  • How To Use
  • When Not to Use
  • Side Effects
  • Precautions & Warnings
  • Drug Interactions
  • Food Interactions
  • Storage/Disposal
  • Quick Tips, if any
  • Description

    MEFLOQUIN 250MG Tablet, containing the active ingredient mefloquine, is a medication primarily used to treat and prevent malaria. Its mechanism of action involves interfering with crucial processes within the malaria parasite, specifically targeting the asexual stages of the parasite's lifecycle. Mefloquine disrupts the parasite's ability to remove waste products, hindering its growth and survival. It achieves this by inhibiting the plasmodial enzyme heme polymerase, leading to the accumulation of toxic heme products within the parasite. This interference ultimately results in the parasite's demise, thereby treating the malaria infection.

  • Ingredients

    MEFLOQUIN
  • Drug Class

    Antimalarial medication

  • Dosage Form

    Tablet

  • Uses

    The following are the uses of MEFLOQUIN 250MG Tablet:

    • Used for treating and preventing malaria
    • Used to prevent and treat a specific type of infection called falciparum malaria
    • Used to reduce the risk of malaria transmission in areas with known resistance to other antimalarial drugs
    • Used for prophylaxis in travelers visiting regions with known malaria activity
    • Used to manage acute attacks of malaria, especially in severe cases
    • Used as an alternative treatment when other antimalarial medications are ineffective or cannot be used
    • Used for short-term treatment, typically for 3-4 months for prophylaxis and up to 28 days for treatment of acute malaria.
  • In case of Overdose

    In the case of an overdose of Mefloquin 250mg tablets, it is important to recognize the potential severity of the situation. Symptoms may include dizziness, nausea, vomiting, and in severe cases, seizures or difficulty breathing. Promptly seek medical assistance and inform healthcare professionals about the overdose. They will provide necessary guidance and treatment to manage the overdose effectively, ensuring the patient's safety and well-being. It is crucial to act quickly and not delay seeking medical help.

  • Missed Dose

    In the case of a missed dose of MEFLOQUIN 250MG Tablet, it is important to take the medication as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you miss multiple doses, contact your healthcare provider for guidance on how to safely resume your medication regimen. It is recommended to set reminders or use a pill organizer to help you remember to take your medication on time.

  • How To Use

    To take MEFLOQUIN 250MG Tablet, swallow the tablet whole with a full glass of water, preferably at the same time each day, following the dosage instructions provided by your healthcare professional, typically taken once weekly as directed.

  • When Not to Use

    Following are the conditions or circumstances when MEFLOQUIN 250MG Tablet should not be taken:

    • Avoid in individuals with a known hypersensitivity or allergy to mefloquine or related compounds.
    • Do not use if there is a history of seizures or epilepsy.
    • Contraindicated in individuals with major psychiatric disorders or a history of severe mental health problems.
    • Should not be taken by patients with severe liver disease or impaired liver function.
    • Not recommended for individuals with a history of heart rhythm problems or a prolonged QT interval.
    • Avoid in patients with severe kidney disease or poor kidney function.
    • Do not use for malaria prevention or treatment during episodes of psychosis.
    • Not suitable for children under 15 kg (33 lbs) or under 3 months of age.
  • Side Effects

    The side effects of MEFLOQUIN 250MG Tablet may include:

    • Visual disturbances, such as blurred vision or sensitivity to light.
    • Nausea and vomiting.
    • Diarrhea.
    • Dizziness or loss of balance.
    • Headaches.
    • Difficulty sleeping (insomnia).
    • Vivid dreams or nightmares.
    • Confusion or disorientation.
  • Precautions & Warnings

    Following are the precautions and warnings for MEFLOQUIN 250MG Tablet:

    • Not recommended for individuals with a history of seizures, epilepsy, or other neurological disorders, as it may lower the seizure threshold.
    • Patients with a history of mental health issues like depression, anxiety, or psychosis should exercise caution and inform their doctor before starting this medication.
    • Avoid driving or operating heavy machinery as it may cause dizziness, blurred vision, or a loss of balance.
    • Should be used with caution in elderly patients, as they may be more susceptible to side effects and adverse reactions.
    • Not suitable for individuals with liver disease or impairment, as Mefloquine is primarily metabolized by the liver.
    • If any unusual changes in mood or behavior occur, such as anxiety, depression, or confusion, medical advice should be sought immediately.
    • Not recommended for long-term use, and regular medical check-ups are advised to monitor for any adverse effects.
  • Drug Interactions

    Following are the drug interactions for MEFLOQUIN 250MG Tablet:

    • Antacids containing magnesium or aluminum can reduce the absorption of Mefloquine, leading to decreased effectiveness. Take Mefloquine at least 6 hours before or after these antacids.
    • Concomitant use with quinine may increase the risk of seizures and other central nervous system side effects. Monitor for increased adverse reactions.
    • Mefloquine can decrease the effectiveness of oral contraceptives, potentially resulting in unintended pregnancy. Consider using alternative contraceptive methods during and after Mefloquine treatment.
    • The use of Mefloquin with beta-blockers may increase the risk of cardiac conduction abnormalities and heart rhythm issues. Close monitoring is advised.
    • Drug interactions with anti-epileptic medications, such as phenytoin or carbamazepine, can reduce Mefloquine's effectiveness. Regular monitoring of Mefloquine levels may be necessary.
    • Mefloquine may enhance the effects of warfarin, a blood thinner, potentially increasing the risk of bleeding. Regular monitoring of coagulation parameters is recommended.
    • Caution is advised when combining Mefloquine with other medications that prolong the QT interval, as this may increase the risk of cardiac arrhythmias.
  • Food Interactions

    Following are the food interactions for MEFLOQUIN 250MG Tablet:

    • Consuming grapefruit or grapefruit juice should be avoided as it can decrease the elimination of Mefloquine, leading to increased drug levels and potential toxicity.
    • Alcohol consumption should be minimized or avoided as it can enhance the risk of central nervous system side effects like dizziness, confusion, and impaired coordination.
    • Fatty meals might slightly decrease the absorption of Mefloquine, but this effect is not clinically significant, and the drug can be taken with or without food.
    • Caffeine intake should be moderated as Mefloquine may increase caffeine levels in the body, potentially causing jitteriness and sleep disturbances.
    • Dairy products with high-fat content might temporarily delay Mefloquine absorption, but this is not a major concern and the drug can be taken with milk if needed.
    • Avoid large quantities of black pepper as the compound piperine may interfere with Mefloquine metabolism, potentially affecting drug levels.
    • There is no specific interaction with sugar, but maintaining a balanced diet is advisable during MEFLOQUIN therapy.
    • Always follow the advice of your healthcare provider regarding dietary considerations while taking this medication.
  • Storage/Disposal

    MEFLOQUIN 250MG Tablets should be stored in a secure and dry location, away from direct sunlight and moisture. Keep the tablets in their original packaging, ensuring the container is tightly sealed to maintain their integrity. It is crucial to store medications in a controlled environment, avoiding extreme temperatures and humidity. Always check the expiration date before use and dispose of any unused or expired tablets responsibly. Do not dispose of them in household waste or flush them down the toilet; instead, follow local guidelines or consult your pharmacist for appropriate disposal methods. Keep this medication out of children's reach to prevent accidental consumption.

  • Quick Tips, if any

    Following are the quick tips for MEFLOQUIN 250MG Tablet:

    • Take the tablet as directed by your doctor, usually once weekly or as prescribed.
    • Consume the tablet with a full glass of water, preferably with a meal or snack to prevent stomach upset.
    • Start taking this medication 1-2 weeks before traveling to an area where malaria is prevalent.
    • Continue taking the tablet regularly during your stay and for 4 weeks after leaving the area.
    • Store the medication at room temperature, away from moisture and light.
    • Do not share this medication with others, even if they have similar symptoms.
    • Inform your doctor if you have a history of mental health issues or seizures before taking this medication.

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