Lerace (250mg) 10 Tablets

Levetiracetam is an anticonvulsant drug that has proven effective in treating seizures and epilepsy. It accomplishes this by reducing the excitement of neurons in the brain, which helps control seizures and prevention of epilepsy. The drug's mechanism of action begins with its binding to the synaptic vesicle protein 2A (SV2A). This protein is involved in regulating neurotransmitter release and is widely distributed throughout the central nervous system. Binding to SV2A has been shown to reduce neurotransmitter release, which is believed to contribute to its anticonvulsant effects. Levetiracetam additionally binds to voltage-gated sodium channels and GABA receptors, which assists in the suppression of excitatory neurotransmitter activity, such as that of glutamate. This suppression of neurotransmitters reduces the likelihood of seizures. It is thought that Levetiracetam also inhibits voltage-gated sodium channels, which are significant in generating epileptic activity. Consequently, blocking these channels reduces the influx of sodium into neurons, decreasing excitability and neuron firing. The complex interactions of Levetiracetam with multiple targets in the brain work together to produce its powerful anticonvulsant effect, making it an invaluable treatment option for individuals with epilepsy. It's worth noting that the precise mechanism of action for Levetiracetam is yet fully understood and remains a subject of ongoing scientific inquiry. For more comprehensive and up-to-date information on Levetiracetam, it is recommended to consult a healthcare professional.

Antiepileptic Drug

Unveiling its multifaceted uses and transformative applications as follows:

• Treatment of partial onset seizures, myoclonic seizures and generalized seizures in adults and adolescents aged 12 years and older
• Adjunctive therapy in the treatment of partial onset seizures, primary generalized tonic clonic seizures and myoclonic seizures in adults and children 4 years and older
• Maintenance treatment of Bipolar 1 Disorder to prevent relapse of manic or mixed episodes in adults and adolescents aged 18 years and older

Tailoring Treatment for Optimal Health, Prescribed Medication Dosage is:

• Epilepsy- Initially, 500 mg once daily, then increase to a target dose of 3000• 3600 mg daily in divided doses (e.g. 500 mg, 1000 mg, and 2000 mg taken twice a day)
• Bipolar disorder- Usually between 1000 and 3000 mg daily in divided doses
• Your doctor may gradually increase your dose based on your response to the medication
• Anxiety- Lower doses, ranging from 500 to 1500 mg daily

An overdose of Levetiracetam may cause severe symptoms such as dizziness, nausea, and vomiting. It is crucial to seek immediate medical attention in case of an overdose to prevent the occurrence of more severe symptoms. The treatment involves monitoring vital signs, administering fluids, and treating symptoms. The healthcare team may also induce vomiting to prevent absorption of the drug. However, due to the uniqueness of each overdose case, various interventions may be required to stabilize the patient.

If you miss a dose of levetiracetam, it is important to seek guidance from your medical provider. You may take the missed dose as soon as you remember, unless it is close to the time for your next dose. If so, skip the missed dose and stay on your regular dosage schedule. It is crucial to avoid doubling up on doses to safely use this medication. Follow the dosing schedule exactly as prescribed by your medical professional, as this medication is typically taken multiple times a day to effectively manage your medical condition. If you are unsure about how to take the medication, or if you have missed a dose, contact your medical provider for further guidance. This will ensure optimal management of your condition.

Levetiracetam tablets are a commonly prescribed anti-seizure medication used to treat epilepsy and specific forms of seizures. Before starting your medication, it is crucial to read the Medication Guide, which is provided by your pharmacist and contains essential information about Levetiracetam and proper administration. For adults and children aged 12 and above, the usual starting dose is 500 mg taken twice daily. The dosage for children below 12 years is based on weight and is given twice a day. It is recommended to take Levetiracetam tablets at the same time each day, with or without food, to maintain a consistent level of the drug in the bloodstream. Instead of crushing, breaking, or chewing the tablets, which can impact their absorption, they should be swallowed whole. Continuous use of Levetiracetam is necessary as prescribed by your doctor, even if you feel well. Suddenly stopping the medication may raise the risk of seizures. If a dose is missed, it is advisable to take it as soon as possible. But if it is nearly time for the next scheduled dose, it is better to skip the missed dose and continue with the regular dosing schedule, ensuring never to double up on the dose. LEVETIRACETAM TABLETS should be stored in a cool, dry place away from direct heat and light. The bathroom or proximity to a sink is not ideal for storage. If you encounter any concerns or adverse effects while taking Levetiracetam, it is vital to consult your healthcare professional. Remember, your healthcare provider is your primary source for questions and guidance specific to your condition and treatment regimen. It is essential to consult with them regarding any concerns or side effects you may experience while taking Levetiracetam tablets.

Discerning instances where this medication may not be appropriate:

• You are allergic to levetiracetam or any of the other ingredients in this medication.
• You have kidney disease or kidney failure.
• You have liver disease or liver failure.
• You have a history of depression or suicidal thoughts.
• You are pregnant or planning to become pregnant.
• You are breastfeeding.
• You have a history of substance abuse.
• You have a serious or uncontrolled seizure disorder.
• You have a serious infection.
• You have a serious injury or surgery scheduled.

Unraveling the side effects lurking behind this medications are as follows:

• Mood changes, including depression and suicidal thoughts
• Problems with attention and memory
• Hallucinations (seeing, hearing, or feeling things that are not there)
• Speech problems or struggles with understanding others
• Slow or abnormal eye movements
• Upset stomach and nausea
• Vomiting
• Diarrhea
• Constipation
• Loss of appetite
• Weight gain or weight loss
• Sleepiness or trouble sleeping
• Irritability
• Aggression
• Anxiety
• Confusion
• Back pain
• Muscle aches or weakness
• Joint pain
• Nosebleeds
• Stuffy nose
• Sore throat
• Ear pain or trouble hearing
• Weird tastes in the mouth
• Swelling of the lips, face, or throat
• Very high blood pressure leading to strokes
• Slow or irregular heartbeat
• Tremors
• Seizures

Here are some important precautions and warnings that patients should be aware of:

• Patients with QTc-interval prolongation, pre-existing cardiac disease, or electrolyte disturbances should be closely monitored.
• When switching between oral and IV forms, the total daily dose and administration frequency should be the same or maintained.
• Avoid abrupt withdrawal of the medication to prevent adverse effects.
• Caution is advised for patients with renal and severe hepatic impairment.
• Extra care is necessary when administering the medication to children.
• Special considerations are required during pregnancy and lactation.

Drug interactions with levetiracetam include:

• Other antiepileptics (e.g., phenytoin, carbamazepine) (may require dose adjustments- monitor for changes in seizure control)
• Oral contraceptives (generally no significant interaction, but monitoring is recommended)
• Warfarin (generally no significant interaction, but monitoring for bleeding risk is advisable)
• Alcohol (may increase the risk of CNS side effects- monitor for increased sedation or dizziness)
• Renal impairment (may require dose adjustments- monitor renal function and adjust dosage as needed)
• CNS depressants (e.g., benzodiazepines) (may enhance CNS depressant effects- monitor for increased sedation)

Levetiracetam is an anticonvulsant medication used for the treatment of seizures and epilepsy. It is available in different forms including tablets, liquid, and extended-release capsules. When it comes to storing these medication forms, there are several important guidelines to follow to ensure their effectiveness and safety. To start, levetiracetam should always be stored in its original container, ensuring it is tightly closed or sealed. It should be kept in a cool, dry place, away from children's reach. Areas susceptible to temperature changes, such as near a stove, refrigerator, or any sources of water should be avoided as this may affect the drug's stability due to moisture buildup or temperature fluctuations. Additionally, direct sunlight or exposure to bright light, such as bathroom storage, should be avoided as it can degrade the medication. For the best results, levetiracetam should be stored at room temperature, ideally between 68°F to 77°F (20°C to 25°C). While checking the medication label or the patient information leaflet, one should look for any specific storage instructions provided by the manufacturer. Finally, as with any medication, it is important to dispose of levetiracetam tablets and capsules safely and according to the recommended medication disposal guidelines of your country. By following these storage instructions, you can ensure that levetiracetam remains effective and safe for use. If you have any questions or concerns about storing this medication, it is best to consult your pharmacist or physician.