Lescol (20mg) 28 Capsules

Fluvastatin, the active ingredient in Fluvastatin 20mg Capsules, primarily works by inhibiting HMG-CoA reductase, a key enzyme in the liver responsible for cholesterol production. By competitively blocking this enzyme, fluvastatin reduces the production of cholesterol, including low-density lipoprotein (LDL) cholesterol. This inhibition leads to a decrease in the levels of total cholesterol and LDL cholesterol in the blood. Additionally, fluvastatin can modestly increase high-density lipoprotein (HDL) cholesterol and decrease triglyceride levels, further contributing to its lipid-lowering effects. The overall mechanism of action helps in managing hyperlipidemia and reducing the risk of cardiovascular events by improving the lipid profile in the bloodstream.

Fluvastatin 20mg

Statin

Capsule

The following are the uses of Fluvastatin 20mg Capsule:

• Used for lowering high cholesterol and reducing the risk of heart disease.
• Used for managing hyperlipidemia, a condition with high levels of fats in the blood.
• Used for preventing the progression of atherosclerosis, which is the buildup of plaque in arteries.
• Used for reducing the chances of heart attacks and strokes in high-risk individuals.
• Used for controlling high triglyceride levels in the blood.
• Used for improving overall cardiovascular health and blood circulation.
• Used for long-term management of lipid disorders, under medical supervision.
• Used for patients who haven't responded adequately to lifestyle changes alone.

In the case of an overdose of Fluvastatin 20mg Capsules, it is important to act swiftly. The severity of symptoms can vary, including nausea, dizziness, and muscle pain. Immediate medical assistance is necessary, and healthcare professionals should be contacted without delay. They will provide guidance on the best course of action, which may include inducing vomiting or administering activated charcoal to prevent further absorption. Prompt action can significantly impact the outcome and minimize potential health risks.

In the case of a missed dose of Fluvastatin 20mg Capsule, it is important to take the medication as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one. If you miss multiple doses, contact your healthcare professional for advice, as they may recommend adjusting your dosage or provide specific instructions for catching up on missed doses safely. It is always best to maintain a consistent medication routine to ensure optimal effectiveness.

To take Fluvastatin 20mg Capsules, swallow the capsule whole with a full glass of water, preferably at the same time each day, either with or without food, as directed by your healthcare provider.

Here are the conditions or situations when Fluvastatin 20mg Capsule should not be taken:

• Must not be used in individuals with a known allergy to Fluvastatin or any HMG-CoA reductase inhibitors (statins).
• Contraindicated in patients with active liver disease or unexplained elevated liver enzymes.
• Should not be used in pregnant or breastfeeding women.
• Not recommended for individuals with a history of muscle pain or disorders, such as myopathy or rhabdomyolysis.
• Avoid using in patients with severe kidney disease or those on dialysis.
• Fluvastatin should not be used in individuals with a history of hereditary muscle disorders.
• Contraindicated in individuals who consume excessive amounts of alcohol or have a history of liver disease related to alcohol.
• Not suitable for people with uncontrolled seizures or epilepsy.

The side effects of Fluvastatin 20mg Capsule may include:

• Muscle pain or weakness
• Joint pain
• Nausea and vomiting
• Diarrhea
• Abdominal pain
• Headache
• Increased liver enzymes (seen in blood tests)
• Skin rash or itching

Following are the precautions and warnings for Fluvastatin 20mg Capsule:

• Not recommended for individuals with known allergies to Fluvastatin or other statins. Discontinue use and seek medical attention if allergic reactions occur.
• Regular liver function tests are necessary during treatment, especially for patients with pre-existing liver conditions. Discontinue use if liver enzymes rise significantly.
• Exercise caution in patients with a history of kidney disease, as dosage adjustments might be required for those with impaired renal function.
• May increase blood sugar levels; diabetes patients should monitor their blood glucose regularly.
• Patients experiencing unexplained muscle pain, tenderness, or weakness should report to their doctor immediately.
• Avoid or limit alcohol consumption as it may increase the risk of liver-related side effects.
• Fluvastatin may cause birth defects; pregnant women or those planning to become pregnant should consult their doctor before use.
• Breastfeeding women should consult their healthcare provider as Fluvastatin may pass into breast milk.

Following are the drug interactions for Fluvastatin 20mg Capsule:

• Gemfibrozil can increase the risk of muscle-related side effects when taken with Fluvastatin, regular monitoring is advised.
• Cyclosporine levels may increase when used with Fluvastatin, requiring close monitoring and dosage adjustments.
• Fluvastatin can increase the concentration of warfarin, enhancing its anticoagulant effect, so regular monitoring of INR is necessary.
• The effectiveness of oral contraceptives may be reduced by Fluvastatin, so alternative contraception methods should be considered.
• Antacids containing aluminum or magnesium can decrease the absorption of Fluvastatin, so they should be taken at least 2 hours apart.
• When combined with colchicine, Fluvastatin may increase the risk of muscle and kidney problems, especially in older patients.
• Caution is advised with immunosuppressants like ciclosporin, as Fluvastatin can increase their blood concentration, requiring dosage adjustments.

Following are the food interactions for Fluvastatin 20mg Capsule:

• Grapefruit and grapefruit juice consumption should be avoided as they can significantly increase the levels of Fluvastatin in the blood, potentially leading to an increased risk of side effects.
• Alcohol intake should be limited as it can negatively impact the liver, which is crucial for metabolizing Fluvastatin. Excessive alcohol can also increase the risk of liver-related side effects.
• Consuming a high-fat meal may slightly increase Fluvastatin absorption, but this effect is generally not clinically significant.
• Avoid cranberry juice as it may decrease Fluvastatin's effectiveness by affecting the enzymes responsible for its metabolism.
• Vitamin K-rich foods like leafy greens should be consumed consistently to maintain stable levels, as Fluvastatin can interfere with Vitamin K metabolism.
• Ensure a balanced diet to maintain a healthy weight, as Fluvastatin is often used in conjunction with lifestyle changes for cholesterol management.
• Avoid high-sodium foods as Fluvastatin may interact with sodium levels in the body.
• Always follow dietary advice from your healthcare provider when taking Fluvastatin.

Fluvastatin 20mg capsules should be stored in a cool and dry place, preferably at room temperature, ensuring protection from light and moisture. Keep the medication in its original container, tightly sealed, to maintain its integrity and prevent contamination. Avoid exposure to heat sources like radiators or stoves, as this can impact the medicine's effectiveness. Dispose of any unused or expired capsules responsibly; do not flush them or pour them down the drain. Consult your pharmacist for guidance on proper disposal. It's crucial to keep the medication out of children's reach to prevent accidental consumption. Always refer to the packaging for specific storage instructions and expiration dates.

Following are the quick tips for Fluvastatin 20mg Capsule:

• Take the capsule as directed by your doctor, usually once daily.
• Swallow the capsule whole; do not crush, chew, or open it.
• Take it at the same time each day to maintain consistent blood levels.
• Can be taken with or without food, but taking it with a meal may reduce the risk of stomach upset.
• Avoid grapefruit and grapefruit juice as they can affect how the medication works.
• Inform your doctor if you have any muscle pain, weakness, or dark-colored urine.
• Store the capsules in a cool, dry place, away from direct sunlight and moisture.