Lescol XL (80mg) 28 Tablets

Fluvastatin 80mg Tablet primarily works by inhibiting HMG-CoA reductase, a crucial enzyme in the liver responsible for catalyzing the conversion of HMG-CoA (3-hydroxy-3-methylglutaryl-coenzyme A) to mevalonate, an early and rate-limiting step in cholesterol biosynthesis. By blocking this enzyme, fluvastatin significantly reduces the production of mevalonate, which in turn lowers the synthesis of cholesterol in the body. This mechanism is particularly effective in reducing low-density lipoprotein (LDL) cholesterol levels, often referred to as 'bad' cholesterol, as well as triglycerides, while also increasing high-density lipoprotein (HDL) cholesterol, known as 'good' cholesterol. The reduction in LDL cholesterol and triglycerides, and the increase in HDL cholesterol, contribute to the overall cardioprotective effect of fluvastatin, helping to prevent atherosclerosis and reduce the risk of cardiovascular events.

Fluvastatin 80mg

Statin

Tablet

The following are the uses of Fluvastatin 80mg Tablet:

• Used for lowering high cholesterol levels and reducing the risk of heart disease.
• Used to slow down plaque buildup in arteries, preventing heart attacks and strokes.
• Used to manage hyperlipidemia, a condition with high levels of bad cholesterol (LDL).
• Used to increase good cholesterol (HDL) and lower triglyceride levels.
• Used to treat patients with a family history of high cholesterol or heart disease.
• Used to support lifestyle changes for heart health, along with diet and exercise.
• Used to reduce the risk of cardiovascular events in patients with established heart disease.
• Used for long-term management of cholesterol levels under medical supervision.

In the case of an overdose of Fluvastatin 80mg Tablets, individuals may experience a range of symptoms. These can include muscle pain, liver problems, and gastrointestinal issues such as nausea, vomiting, and diarrhea. It is important to recognize that an overdose may lead to serious health complications. Promptly seeking medical advice and care is essential if an overdose is suspected, as treatment options may vary depending on the severity of the symptoms and the individual's overall health condition.

In the case of a missed dose of Fluvastatin 80mg Tablet, it is important to take the medication as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you miss multiple doses, contact your healthcare provider for guidance, as they may recommend adjusting your dosage or provide specific instructions to ensure you receive the intended benefits of the medication.

To take Fluvastatin 80mg Tablet, swallow the tablet whole with a full glass of water, preferably at the same time each day, either with or without food, as directed by your healthcare professional, ensuring you follow the prescribed dosage instructions provided by your doctor.

Following are the conditions when Fluvastatin 80mg Tablet should not be taken:

• Should not be used in individuals with a known allergy to Fluvastatin or any HMG-CoA reductase inhibitors.
• Not recommended for patients with active liver disease or persistent elevations in liver enzymes.
• Contraindicated in individuals with severe kidney disease or those with a history of serious kidney problems.
• Should not be used in pregnant or breastfeeding women.
• Not suitable for individuals with a history of muscle pain or weakness, or those who are at risk of developing rhabdomyolysis.
• Avoid using Fluvastatin if you have a history of autoimmune diseases, such as lupus or scleroderma.
• Contraindicated in patients with a history of unexplained elevated creatine kinase (CK) levels.
• Should not be used in patients with uncontrolled seizures or epilepsy.

The side effects of Fluvastatin 80mg Tablet may include:

• Muscle pain and weakness
• Joint pain
• Stomach pain
• Nausea and vomiting
• Diarrhea
• Increased liver enzymes
• Fatigue
• Headache

Following are the precautions and warnings for Fluvastatin 80mg Tablet:

• Individuals with known allergies to Fluvastatin or related medications should not take this tablet.
• Patients with liver disease or a history of liver problems should use with caution and under medical supervision as it can affect liver function.
• Regular monitoring of liver function tests is recommended during treatment.
• This medication may increase blood sugar levels, so diabetic patients should monitor their blood glucose levels closely.
• Caution is advised when taking Fluvastatin with other medications, especially those that can interact and increase the risk of muscle problems.
• Patients experiencing unexplained muscle pain, tenderness, or weakness should seek medical attention immediately.
• Not recommended for use during pregnancy and breastfeeding unless the potential benefits outweigh the risks.
• Patients with a history of kidney problems should inform their doctor as Fluvastatin dosage may need adjustment.

Following are the drug interactions for Fluvastatin 80mg Tablet:

• Gemfibrozil can increase the risk of muscle-related side effects when taken with Fluvastatin, regular monitoring is advised.
• Fluvastatin may increase blood levels of warfarin, an anticoagulant, potentially affecting the international normalized ratio (INR) and bleeding risk.
• When used with other cholesterol-lowering medications like colestipol or cholestyramine, Fluvastatin should be taken at a different time to ensure proper absorption.
• Cyclosporine levels may be increased by Fluvastatin, leading to potential toxicity.
• The effectiveness of hormonal contraceptives may be reduced by Fluvastatin.
• Interactions with certain HIV protease inhibitors, such as ritonavir, can increase Fluvastatin levels, requiring dosage adjustments.
• Macrolide antibiotics like erythromycin can increase Fluvastatin concentrations, necessitating careful monitoring.

Following are the food interactions to be aware of when taking Fluvastatin 80mg Tablets:

• Grapefruit and grapefruit juice consumption should be avoided as they can increase Fluvastatin levels in the blood, potentially leading to an increased risk of side effects.
• Alcohol intake should be minimized or avoided as it can negatively impact the liver, which is crucial for metabolizing Fluvastatin.
• High-fat meals may slightly delay the absorption of Fluvastatin, but they do not significantly affect its overall effectiveness.
• Avoid cranberry juice as it may affect Fluvastatin's metabolism, leading to increased drug levels in the body.
• Limit green tea consumption as it may interfere with Fluvastatin's metabolism and increase the risk of side effects.
• Licorice consumption should be cautious as it can potentially interact with Fluvastatin, affecting its metabolism.
• Be cautious with garlic supplements as they may have a mild interaction, affecting Fluvastatin's blood levels.
• Always consult your healthcare provider for personalized advice on dietary adjustments while taking Fluvastatin.

Fluvastatin 80mg Tablets should be stored in a secure and dry location, preferably in a medicine cabinet or designated storage area, away from direct sunlight, moisture, and heat. It is crucial to keep the tablets in their original packaging or container, tightly sealed, to maintain their integrity and prevent exposure to external factors. Do not transfer the tablets to a different container as it may lead to mix-ups or contamination. Always check the expiration date before taking any medication, and if the tablets are past their expiry, dispose of them properly. Dispose of any unused or expired medication through designated medication disposal programs or by returning them to a pharmacy, ensuring they are not thrown in the trash or flushed down the toilet to prevent environmental contamination. Keep the medication out of the reach of children and pets to avoid accidental ingestion.

Following are the quick tips for Fluvastatin 80mg Tablet:

• Consult your doctor for the right dosage and duration based on your medical condition.
• Take the tablet at the same time each day to maintain consistent blood levels.
• Swallow the tablet whole with a full glass of water; do not crush, chew, or break it.
• Take the medication regularly to maximize its effectiveness; do not skip doses.
• Inform your doctor about all the medications you are taking to avoid potential drug interactions.
• Do not take this medicine if you are pregnant, breastfeeding, or planning to become pregnant without medical advice.
• Store Fluvastatin 80mg Tablets at room temperature, away from moisture and direct sunlight.