Levaq (125mg/5ml) 60ml Suspension

Levofloxacin 125mg syrup/suspension acts by inhibiting DNA gyrase and topoisomerase IV, essential bacterial enzymes responsible for DNA replication and cell division. It primarily targets these enzymes within bacterial cells, leading to the inhibition of DNA synthesis and subsequent bacterial cell death. This mechanism is highly effective against a broad spectrum of bacteria, making levofloxacin a potent antibiotic for treating various infections.

Levofloxacin 125mg

Fluoroquinolone antibiotic.

Suspension

The following are the uses of Levofloxacin 125mg Syrup/Suspension:

• Used for treating bacterial infections such as pneumonia, bronchitis, and sinusitis.
• Used for managing acute exacerbations of chronic bronchitis.
• Used for treating skin and skin structure infections.
• Used for treating certain urinary tract infections.
• Used for managing community-acquired pneumonia.
• Used for treating respiratory tract infections caused by susceptible bacteria.
• Used for controlling bacterial growth in severe bacterial infections.

In the case of an overdose of Levofloxacin 125mg Syrup/Suspension, individuals may experience severe side effects. These can include gastrointestinal symptoms such as nausea, vomiting, and diarrhea, as well as more serious complications like seizures, confusion, and kidney problems. It is important to recognize the signs of an overdose and seek medical assistance promptly. Timely intervention can help manage the symptoms and prevent potential long-term health consequences.

In the case of a missed dose of Levofloxacin 125mg Syrup/Suspension, it is important to take the missed dose as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one, as this may increase the risk of side effects. If you miss multiple doses, contact your healthcare provider for guidance on how to safely resume your medication. It is crucial to maintain a consistent medication routine for the best treatment outcomes.

To administer Levofloxacin 125mg Syrup/Suspension, shake the bottle well, measure the prescribed dose with the provided measuring device, and give it orally once or twice a day as directed by your healthcare provider, ensuring the entire course is completed.

Following are the conditions/situations when Levofloxacin 125mg Syrup/Suspension should not be used:

• Avoid in individuals with a known allergy or hypersensitivity to Levofloxacin or other quinolone antibiotics.
• Do not use in children and adolescents under 18 years of age, as it can affect growing bones and joints.
• Contraindicated in patients with a history of tendon disorders or tendon rupture, especially those related to previous fluoroquinolone use.
• Not recommended for individuals with myasthenia gravis, as it may worsen muscle weakness.
• Should not be used in patients with a history of central nervous system disorders such as seizures or epilepsy.
• Avoid in patients with prolonged QT intervals or known heart rhythm disorders.
• Do not prescribe to individuals with severe liver impairment, as dosage adjustment is necessary.
• Contraindicated in patients with a history of sensitivity to light (photosensitivity) while taking quinolones.

The side effects of Levofloxacin 125mg Syrup/Suspension may include:

• Nausea and vomiting
• Diarrhea
• Abdominal pain
• Headache
• Dizziness
• Insomnia
• Skin rashes or itching
• Joint or muscle pain

Following are the precautions and warnings for Levofloxacin 125mg Syrup/Suspension:

• Not suitable for individuals with a known allergy to Levofloxacin or other quinolone antibiotics.
• Should be used with caution in patients with kidney or liver disease, as dosage adjustments may be necessary.
• May cause dizziness or lightheadedness; patients should avoid driving or operating machinery until they know how the medication affects them.
• Avoid excessive exposure to sunlight or UV rays, as Levofloxacin may increase skin sensitivity.
• Not recommended for children, adolescents, pregnant or breastfeeding women, and elderly patients without medical advice.
• May cause tendonitis or tendon rupture, especially in patients over 60 years old; any tendon pain or discomfort should be reported to the doctor immediately.
• Discontinue use and seek medical attention if severe diarrhea, seizures, or signs of an allergic reaction occur.
• Inform your doctor about all other medications you are taking to avoid potential drug interactions.

Following are the drug interactions for Levofloxacin 125mg Syrup/Suspension:

• Levofloxacin may interact with antacids containing aluminum, magnesium, or calcium, as well as sucralfate, reducing the absorption of the antibiotic and decreasing its effectiveness.
• Concurrent use with warfarin may increase the risk of bleeding due to Levofloxacin’s potential to enhance the anticoagulant effects of warfarin.
• Caution is advised when using Levofloxacin with other medications that prolong the QT interval (e.g., antiarrhythmics, certain antipsychotics), as this combination may increase the risk of serious heart rhythm disturbances, such as torsades de pointes.
• Levofloxacin can increase the levels of drugs metabolized by the liver, such as cyclosporine, leading to an increased risk of side effects or toxicity.
• Combining Levofloxacin with nonsteroidal anti-inflammatory drugs (NSAIDs) may increase the risk of central nervous system (CNS) side effects, such as seizures.
• Levofloxacin may interact with corticosteroids (e.g., prednisone), increasing the risk of tendonitis or tendon rupture.
• Taking Levofloxacin with caffeine or other stimulants may increase the risk of central nervous system (CNS) side effects, such as agitation or nervousness.
• The use of Levofloxacin with other antibiotics that affect the same bacterial spectrum (e.g., penicillins, cephalosporins) may result in an additive effect, increasing the risk of side effects or toxicity.
• Levofloxacin may reduce the efficacy of oral contraceptives, so additional contraception methods should be considered during treatment.

Following are the food interactions for Levofloxacin 125mg Syrup/Suspension:

• Avoid consuming dairy products like milk, yogurt, or cheese within 2 hours before or after taking the medication, as calcium can interfere with the absorption of Levofloxacin.
• Grapefruit and grapefruit juice should be avoided as they can increase the concentration of Levofloxacin in the blood, potentially leading to an increased risk of side effects.
• Limit caffeine intake from coffee, tea, or energy drinks as it may enhance the stimulant side effects of Levofloxacin, causing jitters or an irregular heartbeat.
• Alcohol consumption should be minimized or avoided as it can increase the risk of liver problems and may also enhance the nervous system side effects of Levofloxacin, such as dizziness and sleep disturbances.
• Avoid high-sugar foods and beverages, especially those containing sucrose or glucose, as they can interact with the medication and reduce its effectiveness.
• Ensure a balanced diet rich in fiber, lean proteins, and complex carbohydrates to support overall health and minimize potential gastrointestinal side effects.
• Stay well-hydrated by drinking plenty of water, especially when taking this medication, to aid in its absorption and reduce the risk of kidney-related side effects.
• There are no specific food restrictions, but maintaining a healthy and varied diet is recommended to support the body's overall well-being during the course of treatment.

Levofloxacin 125mg Syrup/Suspension should be stored in a cool and dry environment, preferably at room temperature, ensuring it is protected from direct sunlight and moisture. Keep the medication securely sealed within its original packaging to maintain its integrity and prevent contamination. Avoid storing it in areas like bathrooms or near heat-emitting appliances, as temperature fluctuations can impact its effectiveness. Prioritize the safe disposal of any unused or expired medication; refrain from flushing it down the toilet or draining it. Consult your pharmacist or healthcare professional for appropriate disposal practices. It is crucial to keep the medication out of children's reach to prevent accidental consumption.

Following are the quick tips for Levofloxacin 125mg Syrup/Suspension:

• Always take the medication as directed by your doctor; do not adjust the dosage without medical advice.
• Ensure the syrup is well shaken before each use to maintain consistency.
• Administer the syrup using the provided measuring device for accurate dosing.
• Consume the syrup at evenly spaced intervals to maintain a steady drug level.
• Store the medication at room temperature, away from excessive heat, light, and moisture.
• Dispose of any unused or expired medication safely and appropriately.
• Inform your doctor if you have any known allergies before taking this medication.