Desloratadine is a second generation tricyclic histamine receptor antagonist. It is an active descarboethoxy metabolite of loratadine. Desloratadine is a non-sedating, long-acting acting histamine antagonist with selective peripheral H1-receptor antagonist activity. Desloratadine after oral administration; selectively blocks peripheral histamine H1-receptors because it does not enter the central nervous system; that's why it does not cause drowsiness.
Uses
Used to treat symptoms of allergy like; runny nose, watery eyes, sneezing. Aids in relief of nasal and non-nasal symptoms of seasonal and perennial Allergic Rhinitis. Treats chronic spontaneous Urticaria and Hives.
Dose
Dose must be taken according to doctor’s advice only; doses given below are suggested as supportive literature for better understanding in some areas of requirements. For adults and children of age above 12 years: 5mg daily.
Over Dose
Symptomatic and supportive measures should be taken after overdose. Dose of 250mg/kg or above is lethal.
Missed Dose
In case you missed any dose, take the next dose as soon as you remember, but don't double your next dose to compensate for the missed one.
How To Use
Take orally after a meal or as your doctor prescribed.
When Not Use
Should not be given to patients with hypersensitivity to loratadine or desloratadine or any of its component mixture.
Precautions
Dose should be adjusted in patients with liver or kidney problems.