Lexttor (6mg) 30 Tablets

Lexttor (6mg) 30 Tablets

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  • Manufacturer Wilshire
  • Generic Name Tegaserod

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Product Information

  • Description
  • Ingredients
  • Drug Class
  • Dosage Form
  • Uses
  • Dosage
  • In case of Overdose
  • Missed Dose
  • How To Use
  • When Not to Use
  • Side Effects
  • Precautions & Warnings
  • Drug Interactions
  • Food Interactions
  • Storage/Disposal
  • Quick Tips, if any
  • Laboratory Screening
  • Description

    Tegaserod, a 5-HT4 receptor partial agonist, primarily exerts its effect by activating these receptors in the gastrointestinal tract. This activation enhances the release of neurotransmitters like acetylcholine, which stimulate intestinal motility. Specifically, tegaserod accelerates gastrointestinal motility, reduces visceral sensitivity, and normalizes irregular intestinal muscle layer contractions, thereby improving overall gastrointestinal function. Its selective action on 5-HT4 receptors contributes to the relief of gastrointestinal symptoms without significantly impacting other systems.

  • Ingredients

    Tegaserod
  • Drug Class

    Serotonin receptor agonist.

  • Dosage Form

    Tablet

  • Uses

    The following are the uses of Tegaserod 6MG Tablet:

    • Used for treating chronic constipation, offering relief from symptoms.
    • Used for managing irritable bowel syndrome (IBS) in women by improving bowel movements and reducing abdominal pain.
    • Used for stimulating intestinal muscle contractions, aiding digestion and waste elimination.
    • Used for restoring normal bowel function and reducing straining during defecation.
    • Used for improving overall gastrointestinal health and reducing bloating and discomfort.
    • Used for enhancing the absorption of nutrients from food, promoting better overall health.
    • Used for providing relief from constipation-related symptoms like nausea and fatigue.
  • Dosage

    Dose must be taken according to doctor’s advice only; doses given below are suggested as supportive literature for better understanding in some areas of requirements. For adults and children of age above 12 years: 5mg daily.
  • In case of Overdose

    In the case of an overdose of Tegaserod 6MG Tablets, it is important to recognize the potential symptoms and seek medical advice promptly. Overdosing may lead to severe gastrointestinal disturbances, including intense abdominal pain, nausea, and diarrhea. Additionally, individuals may experience dizziness, rapid heartbeat, and, in extreme cases, seizures. Prompt medical intervention is advised to manage these symptoms effectively and prevent any potential long-term complications associated with excessive Tegaserod intake.

  • Missed Dose

    In the case of a missed dose of Tegaserod 6MG Tablet, it is important to take the medication as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one, as this may increase the risk of side effects. If you frequently miss doses, consider setting reminders or using a pill organizer to help you stay on track with your medication routine. It is advisable to consult your healthcare provider if you have any concerns or if you miss multiple doses.

  • How To Use

    To take Tegaserod 6MG Tablet, swallow the tablet whole with a full glass of water, preferably at the same time each day, as directed by your healthcare professional, without crushing or chewing the tablet.

  • When Not to Use

    Following are the conditions when Tegaserod 6MG Tablet should not be taken:

    • Avoid if allergic to Tegaserod or similar medications.
    • Do not use if you have a history of heart-related conditions such as high blood pressure, heart attack, or stroke.
    • Contraindicated in individuals with severe kidney or liver disease.
    • Not suitable for women who are pregnant or breastfeeding.
    • Should not be used in children and adolescents under 18 years of age.
    • Avoid if you have or have had a bowel obstruction or gastrointestinal perforation.
    • Do not take if you have experienced diarrhea caused by antibiotics or other medications.
    • Contraindicated in individuals with a history of abdominal surgeries or procedures.
  • Side Effects

    The side effects of Tegaserod 6MG Tablet may include:

    • Diarrhea
    • Abdominal pain
    • Nausea and vomiting
    • Headache
    • Dizziness
    • Fatigue
    • Constipation
  • Precautions & Warnings

    Following are the precautions and warnings for Tegaserod 6MG Tablet:

    • This medication is not recommended for individuals with a history of hypersensitivity or allergic reactions to Tegaserod or any of its ingredients.
    • Patients with gastrointestinal conditions such as inflammatory bowel disease, gastrointestinal bleeding, or severe constipation should use this medication with caution, and regular monitoring is advised.
    • Tegaserod may cause dizziness or lightheadedness in some individuals; patients should be cautious when performing tasks that require alertness, such as driving or operating heavy machinery.
    • Elderly patients may be more susceptible to the adverse effects of this medication, and dosage adjustments might be necessary.
    • Patients with a history of cardiovascular disease should be closely monitored as Tegaserod has been associated with an increased risk of cardiovascular events.
    • It is important to maintain adequate hydration while taking this medication to minimize the risk of constipation.
    • If symptoms worsen or persist, or if new abdominal symptoms develop, patients should seek medical advice immediately.
    • Tegaserod is not recommended for use in children and adolescents under 18 years of age.
  • Drug Interactions

    Following are the drug interactions for Tegaserod 6MG Tablet:

    • Tegaserod can interact with other gastrointestinal prokinetic agents, such as Cisapride, potentially leading to cardiac arrhythmias.
    • Concomitant use with strong CYP450 3A4 inhibitors like Ketoconazole may increase Tegaserod levels, leading to enhanced side effects.
    • Tegaserod may reduce the absorption of orally administered medications, such as antibiotics and antifungals, affecting their efficacy.
    • The effectiveness of oral contraceptives may be reduced when taken with Tegaserod, requiring additional contraceptive measures.
    • Use with other medications that prolong QT intervals, like certain antiarrhythmic drugs, should be avoided due to increased cardiac risks.
    • Tegaserod can increase the risk of adverse events when taken with other drugs that have similar side effects, including other 5-HT4 receptor agonists.
    • It may also interact with drugs that affect gastrointestinal motility, potentially altering the absorption and effectiveness of these medications.
  • Food Interactions

    Following are the food interactions for Tegaserod 6MG Tablet:

    • Grapefruit and grapefruit juice consumption should be avoided as they can inhibit the enzyme CYP3A4, leading to increased Tegaserod levels in the blood and potentially causing adverse effects.
    • Alcohol intake is not recommended with Tegaserod as it may enhance the drug's sedative properties, increasing the risk of dizziness and drowsiness.
    • Avoid high-fat meals as they may decrease the absorption of Tegaserod, reducing its effectiveness.
    • Caffeine-rich beverages like coffee and tea might interfere with Tegaserod's action, and moderation is advised.
    • Consuming spicy foods while on Tegaserod may aggravate gastrointestinal symptoms, so it's best to limit their intake.
    • Dairy products with high-fat content can potentially reduce the absorption of Tegaserod, so consider reducing their consumption during treatment.
    • Always adhere to the dosage and dietary instructions provided by your healthcare professional for optimal results.
  • Storage/Disposal

    Tegaserod 6MG Tablets should be stored in a secure and dry location, preferably at room temperature, ensuring it remains untouched by direct sunlight or moisture. Keep the medication in its original container, tightly sealed, to maintain its integrity and prevent contamination. It's crucial to avoid extreme temperatures, so steer clear of storing it in the bathroom or near heat sources like ovens or heaters. Regularly check the expiration date, and if the medication is no longer needed or has expired, proper disposal is essential. Do not dispose of it via toilet flushing or drainage; instead, consult a pharmacist or healthcare professional for guidance on safe disposal methods. Always ensure that the medication is kept out of children's reach to prevent accidental consumption.

  • Quick Tips, if any

    Following are the quick tips for Tegaserod 6MG Tablet:

    • Consult your doctor before starting this medication and provide a complete medical history.
    • Take the tablet as directed by your doctor, typically twice a day.
    • Swallow the tablet whole with a full glass of water; do not crush, chew, or break it.
    • You can take the tablet with or without food, but taking it with food may help prevent nausea.
    • Avoid alcohol consumption while using this medication as it may worsen side effects.
    • Store the tablets at room temperature, away from moisture and direct sunlight.
    • Do not share this medication with others, even if their symptoms are similar.
  • Laboratory Screening

    To monitor organs performance before and with the use of this drug, go for the following tests: For liver; LFT, Ultrasound. For kidney; Renal Function Test, Ultrasound. For heart: ECG

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