Lovastatin (20mg) 10 Tablets

Lovastatin (20mg) 10 Tablets

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  • Manufacturer ZAFA PHARMACEUTICALS (PVT.) LTD.
  • Generic Name

    Lovastatin 20mg

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Product Information

  • Description
  • Ingredients
  • Drug Class
  • Dosage Form
  • Uses
  • In case of Overdose
  • Missed Dose
  • How To Use
  • When Not to Use
  • Side Effects
  • Precautions & Warnings
  • Drug Interactions
  • Food Interactions
  • Storage/Disposal
  • Quick Tips, if any
  • Description

    Lovastatin 20mg Tablet primarily works by inhibiting an enzyme called HMG-CoA reductase. This enzyme plays a crucial role in the production of cholesterol in the body. By blocking the action of HMG-CoA reductase, lovastatin reduces the production of cholesterol in the liver. Specifically, it decreases the rate of conversion of HMG-CoA (3-hydroxy-3-methylglutaryl-coenzyme A) to mevalonic acid, which is an early and rate-limiting step in cholesterol biosynthesis. This action results in decreased levels of total cholesterol, low-density lipoprotein (LDL) cholesterol, and triglycerides, while increasing high-density lipoprotein (HDL) cholesterol levels in the blood. This mechanism contributes to the medication's effectiveness in lowering blood cholesterol and managing conditions related to high cholesterol.

  • Ingredients

    Lovastatin 20mg

  • Drug Class

    Statin (HMG-CoA reductase inhibitor)

  • Dosage Form

    Tablet

  • Uses

    The following are the uses of Lovastatin 20mg Tablet:

    • Used for lowering high cholesterol levels and reducing the risk of heart disease.
    • Used to slow down the formation of plaque in the arteries.
    • Used to treat high cholesterol in individuals who have not responded to dietary changes alone.
    • Used to prevent cardiovascular events like heart attacks and strokes.
    • Used to manage cholesterol levels in people with a family history of heart disease.
    • Used to lower LDL (bad) cholesterol and triglycerides while raising HDL (good) cholesterol.
    • Used to improve overall heart health and blood circulation.
  • In case of Overdose

    In the case of an overdose of Lovastatin 20mg Tablets, it is important to recognize the potential symptoms, which may include muscle pain, tenderness, or weakness. Nausea, vomiting, and elevated liver enzymes may also occur. If an overdose is suspected, prompt medical advice should be sought, and the individual should be monitored for any signs of liver or muscle damage. It is crucial to act quickly and not delay seeking medical assistance to prevent potential complications.

  • Missed Dose

    In the case of a missed dose of Lovastatin 20mg Tablet, it is recommended to take the medication as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. It is important not to double the dose to make up for a missed one, as this may increase the risk of side effects. If you frequently miss doses, it is advisable to set reminders or use a pill organizer to help you stay on track with your medication regimen.

  • How To Use

    To take Lovastatin 20mg Tablet, swallow the tablet whole with a full glass of water, preferably at the same time each day, following the instructions provided by your healthcare professional, typically taken once daily in the evening, with or without food, as directed by your doctor.

  • When Not to Use

    Following are the conditions when Lovastatin 20mg Tablet should not be taken:

    • Do not take if you are allergic to any component of the medication.
    • Avoid if you have active liver disease or unexplained elevated liver enzymes.
    • Not suitable for individuals with a history of muscle problems caused by a similar type of medication.
    • Should not be used during pregnancy as it may harm the unborn baby.
    • Contraindicated in breastfeeding mothers as it may pass into breast milk and harm the nursing infant.
    • Do not take if you have a genetic muscle disorder or a family history of muscle disorders.
    • Avoid if you have had recent major surgery or trauma.
    • Not recommended for individuals with uncontrolled seizures.
    • Should not be used if you have or have had kidney disease.
    • Do not consume grapefruit juice while taking this medication as it can increase the levels of the drug in the body.
    • Avoid if you have a history of alcohol abuse or liver problems caused by alcohol.
  • Side Effects

    The side effects of Lovastatin 20mg Tablet may include:

    • Muscle pain and weakness
    • Joint pain
    • Constipation or diarrhea
    • Nausea and vomiting
    • Abdominal pain
    • Increased blood sugar levels
    • Liver problems (rare)
    • Skin rash and itching
  • Precautions & Warnings

    Following are the precautions and warnings for Lovastatin 20mg Tablet:

    • Do not take this medication if you are allergic to Lovastatin or any related medications.
    • Regular monitoring of liver function tests is necessary, as Lovastatin can cause liver damage in rare cases.
    • Inform your doctor if you have a history of liver disease or if you consume large quantities of alcohol regularly.
    • This medication may increase blood sugar levels; patients with diabetes should monitor their blood sugar closely.
    • Lovastatin can cause muscle pain and weakness; if you experience severe muscle symptoms, seek medical attention immediately.
    • It may interact with other medications, including certain antibiotics and antifungals; inform your doctor about all medications you are taking.
    • Avoid grapefruit and grapefruit juice while taking Lovastatin, as it can increase the drug's concentration in the body.
    • Consult your doctor if you are pregnant, planning to become pregnant, or breastfeeding, as Lovastatin may have potential risks for the fetus or infant.
  • Drug Interactions

    Following are the drug interactions for Lovastatin 20mg Tablet:

    • Co-administration with cyclosporine, gemfibrozil, or strong CYP3A4 inhibitors (e.g., itraconazole, ketoconazole) can increase the risk of myopathy and rhabdomyolysis.
    • The use of Lovastatin with other HMG-CoA reductase inhibitors (statins) may increase the risk of myopathy and liver enzyme abnormalities.
    • It can interact with anticoagulants like warfarin, possibly increasing the risk of bleeding. Regular monitoring is advised.
    • Lovastatin may increase blood levels of digoxin, requiring dose adjustment.
    • Certain immunosuppressants like ciclosporin can increase Lovastatin levels, leading to increased risk of side effects.
    • Taking Lovastatin with fibrates like gemfibrozil can increase the risk of muscle-related side effects.
    • The use of Lovastatin with niacin may increase the risk of myopathy and rhabdomyolysis.
    • It can interact with certain antibiotics like erythromycin, potentially increasing Lovastatin levels in the body.
  • Food Interactions

    Following are the food interactions for Lovastatin 20mg Tablet:

    • Grapefruit and grapefruit juice consumption should be avoided as they can increase the levels of Lovastatin in the blood, potentially leading to an increased risk of side effects.
    • Alcohol intake should be limited as it can affect the liver's ability to process Lovastatin, increasing the risk of liver-related complications.
    • Avoid excessive consumption of fatty foods, as Lovastatin is better absorbed with a low-fat diet, ensuring optimal therapeutic effect.
    • Avoid eating large amounts of licorice, as it may interfere with the metabolism of Lovastatin, reducing its effectiveness.
    • Limit the intake of red yeast rice products, as they may contain naturally occurring statins, which could lead to an overdose when combined with Lovastatin.
    • Avoid consuming large quantities of cranberry juice, as it may interact with Lovastatin and increase the risk of muscle-related side effects.
    • Be cautious with high-fiber foods; while they are generally healthy, they can interfere with the absorption of Lovastatin, reducing its effectiveness.
    • Always consult your healthcare provider for specific dietary guidelines, as they may provide personalized advice based on your medical history.
  • Storage/Disposal

    Lovastatin 20mg Tablets should be stored in a cool and dry place, preferably at room temperature, ensuring protection from light and moisture. The medication container should be tightly sealed to maintain its integrity and prevent contamination. It is crucial not to store the tablets in the bathroom or near heat sources, as these conditions can degrade the medication. Proper disposal of any unused or expired tablets is essential; avoid flushing or pouring them down the drain. Consult your pharmacist for safe disposal guidelines, and keep the medication away from children to prevent accidental consumption. Always adhere to the recommended storage conditions and exercise caution when handling and disposing of this medication.

  • Quick Tips, if any

    Following are the quick tips for Lovastatin 20mg Tablet:

    • Consult your doctor before starting this medication, especially if you have liver or kidney issues.
    • Take the tablet as directed by your doctor; do not change the dosage without medical advice.
    • Swallow the tablet whole with a full glass of water, preferably at the same time each day.
    • Avoid crushing, chewing, or breaking the tablet, as it may affect its effectiveness.
    • Inform your doctor about all medications you're taking to prevent potential drug interactions.
    • Do not take Lovastatin if you are pregnant, planning to become pregnant, or breastfeeding.
    • Regularly monitor your liver function and report any unusual symptoms to your healthcare provider.

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