Loxiget (0.3%) 5ml Eye Drops

Gatifloxacin, a potent fourth-generation fluoroquinolone, exerts its antimicrobial effect by targeting two crucial bacterial enzymes DNA gyrase and topoisomerase IV. These enzymes play a vital role in bacterial DNA replication and cell division. Gatifloxacin binds to these enzymes, inhibiting their activity and subsequently blocking DNA replication, leading to bacterial cell death. This mechanism of action is particularly effective against a broad spectrum of bacteria, including both Gram-positive and Gram-negative strains, making Gatifloxacin a valuable tool in the treatment of various bacterial infections.

Gatifloxacin

Quinolone antibiotic.

drop

The following are the uses of Gatifloxacin Drop:

• Used for treating bacterial conjunctivitis, an infection of the eye's outermost layer.
• Used for reducing inflammation and preventing potential vision complications.
• Used for eye infections, especially those caused by bacteria susceptible to gatifloxacin.
• Used for treating pink eye (conjunctivitis) and other eye infections.
• Used for reducing the risk of infection after eye surgery or eye injuries.
• Used for preventing eye infections in high-risk situations.
• Used for controlling the progression of certain eye infections.
• Used for improving eye comfort and overall eye health during treatment.

In the case of an overdose of Gatifloxacin Drops, it is important to seek medical advice promptly. Symptoms of an overdose may include severe nausea, vomiting, diarrhea, and potential damage to the liver or kidneys. Do not induce vomiting or administer any treatment without professional guidance. Contact a healthcare professional or a poison control center for immediate assistance and guidance on the necessary steps to take.

In the case of a missed dose of Gatifloxacin Drops, it is important to administer the medication as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. However, do not double the dose to make up for the missed one, as this may increase the risk of side effects. If you have missed multiple doses, contact your healthcare provider for guidance on how to get back on track with your treatment plan. It is advisable to set reminders or use a medication tracking app to help you remember future doses.

To use Gatifloxacin eye drops, gently tilt your head back, pull the lower eyelid down to create a pocket, and hold the dropper close to your eye; then, squeeze the prescribed number of drops into the pocket, blinking gently to allow the medication to spread over the eye surface, and keep your eyes closed for a minute or two to prevent the drops from draining out.

Following are the conditions/situations when Gatifloxacin eye drops should not be used:

• Should not be used in individuals with a known allergy or hypersensitivity to Gatifloxacin or other quinolone antibiotics.
• Not suitable for patients with a history of tendon disorders or tendon rupture after using fluoroquinolone antibiotics.
• Contraindicated in individuals with epilepsy or other seizure disorders.
• Should not be used in patients with myasthenia gravis.
• Not recommended for children and adolescents under 18 years of age.
• Avoid using in patients with a history of sensitivity to any eye drop medications.
• Do not use if the patient is wearing contact lenses, as the drops may contain preservatives that can be absorbed by the lenses.

The side effects of Gatifloxacin Eye Drops may include:

• Eye irritation or redness
• Itching or burning sensation in the eyes
• Temporary blurred vision
• Eye fatigue or discomfort
• Increased sensitivity to light (photophobia)
• Dry eyes
• Allergic reactions, such as skin rash or itching

Following are the precautions and warnings for Gatifloxacin Eye Drops:

• Gatifloxacin eye drops are for external use only and should never be taken by mouth.
• Patients with a known allergy to Gatifloxacin or other quinolone antibiotics should not use this medication.
• It is important to inform your doctor about any eye conditions or injuries before using these drops.
• Contact lenses should be removed before applying the drops and can be reinserted after 15 minutes.
• Discontinue use and seek medical attention if you experience severe eye irritation, pain, or vision changes.
• This medication is not recommended for children, pregnant women, or breastfeeding mothers unless under medical supervision.
• Do not share this medication with others, even if they have similar symptoms, as it may not be suitable for everyone.
• Store the eye drops at room temperature, away from direct sunlight and moisture.

Following are the drug interactions for Gatifloxacin Drops:

• Gatifloxacin may increase the effects of anticoagulants like warfarin, potentially leading to bleeding risks.
• It can reduce the effectiveness of live vaccines, such as the measles vaccine.
• The risk of tendonitis and tendon rupture is elevated when combined with corticosteroids.
• May cause hypoglycemia when used with sulfonylureas or insulin in diabetic patients.
• Probenecid can increase gatifloxacin levels, increasing the risk of side effects.
• Concurrent use with non-steroidal anti-inflammatory drugs (NSAIDs) may increase the risk of central nervous system (CNS) stimulation and seizures.
• Avoid combining with other fluoroquinolones or drugs that prolong the QT interval, as this may lead to cardiac issues.

Following are the food interactions for Gatifloxacin Drops:

• Avoid consuming dairy products like milk, yogurt, or cheese, as these can bind with Gatifloxacin and reduce its absorption.
• Avoid consuming calcium-fortified foods like calcium-enriched juices or cereals as they can decrease the effectiveness of the medication.
• It is advisable to limit the consumption of caffeine while using Gatifloxacin, as it may increase the risk of side effects such as nervousness and tremors.
• Grapefruit and grapefruit juice should be avoided as they can interfere with the breakdown of the drug, leading to higher levels in the blood and potential side effects.
• Alcohol consumption should be minimized as it can increase the risk of central nervous system side effects, such as dizziness and lightheadedness.
• Consuming a high-fat meal before taking Gatifloxacin may slightly delay the absorption of the medication but does not significantly affect its overall effectiveness.
• No significant interaction with other specific foods, but maintaining a balanced diet is recommended for overall health.
• Always follow the advice of your healthcare provider regarding dietary restrictions or recommendations during Gatifloxacin therapy.

Gatifloxacin eye drops should be stored with caution to maintain their effectiveness and safety. Keep the bottle tightly closed in a cool, dry place, preferably at room temperature, and away from direct sunlight or excessive heat. Protect the drops from freezing temperatures as this can affect their consistency. Ensure the drops are kept away from children and pets to prevent accidental exposure. Always check the expiration date, and do not use the drops if they have passed their expiry. Dispose of any unused or expired medication responsibly; do not pour it down the drain or flush it, but rather follow local guidelines for pharmaceutical waste disposal or consult a pharmacist for advice on proper disposal methods.

Following are the quick tips for Gatifloxacin Drop:

• Wash your hands thoroughly before administering the eye drops to maintain hygiene.
• Tilt your head back, gently pull down your lower eyelid, and instill the prescribed number of drops into the eye.
• Avoid touching the dropper tip to your eye or any surface to prevent contamination.
• Close your eyes gently and apply light pressure to the inner corner of the eye for a few minutes to minimize drug absorption into the bloodstream.
• If you wear contact lenses, remove them before using the drops and wait at least 15 minutes after administration before reinserting them.
• Do not rinse the dropper; replace the dropper cap tightly after each use to maintain sterility.
• Store the eye drops at room temperature, away from direct sunlight and moisture, and keep them out of the reach of children.