Lumark Oral Solution 1 s

Levetiracetam is believed to exert its pharmacological action through binding to synaptic vesicle protein 2A (SV2A) in the brain, which is involved in the regulation of synaptic vesicle exocytosis and neurotransmitter release. By binding to SV2A, levetiracetam modulates the release of excitatory neurotransmitters, particularly glutamate. This mechanism is thought to contribute to its antiseizure effects, as it helps reduce excessive neuronal firing and synchronization associated with seizures. The specific binding of levetiracetam to SV2A is considered to be the primary mode of action, although the exact molecular events leading to its therapeutic effects are still being studied.

Levetiracetam 100mg

Anticonvulsant

Solution

The following are the uses of Levetiracetam 100mg Liquid:

• Used for treating partial seizures in adults and children with epilepsy.
• Used to manage seizures associated with Lennox-Gastaut syndrome.
• Used as an adjunctive therapy for myoclonic seizures in patients with juvenile myoclonic epilepsy.
• Used to control and prevent seizures during and after surgery in hospitalized patients.
• Used for short-term treatment of seizures in emergency situations.
• Used to provide rapid control of seizures in acute settings.
• Used in patients who cannot take oral medications, offering a flexible dosing option.

In the case of an overdose of Levetiracetam 100mg Liquid, symptoms may include drowsiness, agitation, aggression, decreased consciousness, respiratory depression, and in severe cases, seizures or loss of consciousness. Prompt medical attention is necessary, and emergency services should be contacted immediately. Treatment for overdose may involve supportive care, monitoring vital signs, and in some instances, administering activated charcoal to prevent further absorption.

In the case of a missed dose of Levetiracetam 100mg Liquid, it is important to take the medication as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not double the dose to make up for a missed one, as this may increase the risk of side effects. If you miss multiple doses, contact your healthcare provider for guidance on how to safely adjust your dosage and get back on track with your medication regimen.

To administer Levetiracetam 100mg Liquid, use the provided measuring device to draw the prescribed amount, and then pour it into a cup or directly into the mouth, ensuring you take the medication as directed by your healthcare provider, typically twice a day, with or without food.

Following are the conditions or situations when Levetiracetam 100mg Liquid should not be taken:

• Do not take if you have a known allergy or hypersensitivity to Levetiracetam or any of its excipients.
• Contraindicated in patients with a history of severe kidney disease or impairment.
• Not recommended for individuals with a history of liver disorders or impaired liver function.
• Avoid if you have a history of blood disorders or low blood cell counts.
• Do not administer if you have a respiratory condition or breathing difficulties.
• Should not be given to patients with a history of psychiatric disorders or suicidal thoughts.
• Contraindicated in individuals with a history of severe allergic reactions or angioedema.

The side effects of Levetiracetam 100mg Liquid may include:

• Dizziness
• Fatigue or weakness
• Irritability and aggression
• Nausea and vomiting
• Diarrhea
• Loss of appetite
• Sleep disturbances, including insomnia or excessive sleepiness
• Skin rash or itching

Following are the precautions and warnings for Levetiracetam 100mg Liquid:

• This medication should not be used if you are allergic to Levetiracetam or any of its ingredients.
• Patients with kidney problems should use with caution and inform their doctor, as dosage adjustments might be necessary.
• Levetiracetam may cause dizziness or drowsiness; avoid driving or operating heavy machinery until you know how the medication affects you.
• Alcohol consumption should be avoided as it may increase the risk of side effects.
• Do not abruptly stop taking Levetiracetam without consulting your doctor, as it may lead to withdrawal seizures.
• Elderly patients should be monitored closely for adverse effects, as they may be more susceptible to certain side effects.
• If you have a history of mental health disorders, inform your doctor as Levetiracetam may cause mood or behavioral changes.
• Store Levetiracetam 100mg Liquid at room temperature, away from direct sunlight and moisture.

Following are the drug interactions for Levetiracetam 100mg Liquid:

• Alcohol consumption may increase the sedative effects of Levetiracetam, leading to impaired coordination and thinking.
• Carbamazepine, phenytoin, and other enzyme-inducing antiepileptic drugs can reduce the effectiveness of Levetiracetam by increasing its metabolism.
• Levetiracetam may decrease the efficacy of hormonal contraceptives, potentially increasing the risk of unintended pregnancy.
• Combining with other CNS depressants like opioids or benzodiazepines can enhance sedation and respiratory depression.
• Warfarin's anticoagulant effect may be altered, requiring close monitoring of INR (International Normalized Ratio).
• Digoxin levels may be affected, requiring monitoring and dose adjustments.
• Drugs that affect renal function can impact Levetiracetam elimination, potentially requiring dosage modifications.

Following are the food interactions for Levetiracetam 100mg Liquid:

• Alcohol should be consumed in moderation as it can impact the effectiveness of Levetiracetam and may increase the risk of side effects.
• Grapefruit and grapefruit juice should be avoided as they can affect the metabolism of Levetiracetam, potentially leading to increased drug levels in the body.
• High-fat meals may slightly decrease the absorption of Levetiracetam, but this effect is generally not clinically significant.
• Levetiracetam can be taken with or without food, but maintaining a consistent routine is advisable.
• Avoid excessive caffeine intake, as it may interact with Levetiracetam and affect seizure control.
• Do not mix the medication with carbonated beverages as it may alter the properties of the liquid medication.
• Herbal supplements like St. John's Wort should be used cautiously as they can influence the effectiveness of Levetiracetam.
• Always consult your healthcare provider for personalized advice regarding dietary restrictions and potential food interactions.

Levetiracetam 100mg Liquid should be stored in a secure and controlled environment, preferably in a locked cabinet or a designated medication storage area. Keep the liquid at room temperature, away from direct sunlight, heat, and moisture, as these conditions can degrade its quality. Ensure the bottle is tightly sealed after each use to maintain its integrity. It is crucial to adhere to the recommended storage guidelines to preserve the medication's effectiveness. When disposing of Levetiracetam Liquid, do not pour it down the drain or flush it in the toilet. Instead, contact your local waste management authority or healthcare provider for instructions on safe disposal methods, ensuring environmental responsibility. Always handle and store medications responsibly, keeping them out of the reach of children and pets to prevent accidental ingestion.

Following are the quick tips for Levetiracetam 100mg Liquid:

• Store the liquid medication at room temperature, away from direct sunlight and moisture.
• Ensure the medication is out of reach of children and pets.
• Always measure the dose accurately using the provided measuring device.
• Administer the liquid slowly and ensure the entire dose is taken.
• Do not mix the medication with other liquids unless instructed by your healthcare provider.
• If you experience difficulty swallowing, you can administer the liquid through a straw.
• Regularly clean the measuring device to maintain hygiene.
• Consult your doctor if you have any concerns or experience persistent side effects.