Lurisa (80mg) 10 Tablets

Lurasidone Hydrochloride 80mg Tablet primarily exerts its therapeutic effects through a combination of partial agonist activity at dopamine D2 receptors and antagonist activity at serotonin 5-HT2A receptors. It selectively binds to these receptors in the brain, particularly in the mesolimbic and mesocortical pathways. By partially activating dopamine D2 receptors, lurasidone stimulates dopamine transmission, which is believed to contribute to its antipsychotic properties. Simultaneously, its blockade of serotonin 5-HT2A receptors helps regulate serotonin signaling, potentially improving mood and reducing psychotic symptoms. This dual mechanism of action is thought to underlie lurasidone's effectiveness in managing schizophrenia and depressive episodes associated with bipolar I disorder.

Lurasidone Hydrochloride 80mg

Antipsychotic medication.

Tablet

The following are the uses of Lurasidone Hydrochloride 80mg Tablet:

• Used for treating schizophrenia, helping patients manage symptoms like hallucinations and delusions.
• Used to stabilize mood in bipolar disorder, reducing manic and depressive episodes.
• Used for improving social functioning and cognitive abilities in patients with mental health disorders.
• Used to address agitation and irritability associated with psychiatric conditions.
• Used for managing severe anxiety and related symptoms in certain patients.
• Used to enhance overall well-being and quality of life in individuals with mental health challenges.
• Used in combination with other medications for comprehensive mental health treatment.

In the case of an overdose of Lurasidone Hydrochloride 80mg Tablets, symptoms may include drowsiness, rapid heartbeat, and dizziness. It is important to recognize the signs of overdose, as it can lead to severe complications. Seek medical assistance immediately if you suspect an overdose, as prompt treatment can mitigate potential health risks. Ingesting multiple tablets or exceeding the prescribed dosage may result in adverse effects, emphasizing the need for careful medication management and awareness of overdose symptoms.

In the case of a missed dose of Lurasidone Hydrochloride 80mg Tablet, it is important to take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you miss several doses, contact your healthcare provider for advice on how to safely resume your medication regimen. It's crucial to maintain consistency with this medication, so try to set a routine to help you remember to take it at the same time each day.

To take Lurasidone Hydrochloride 80mg Tablet, swallow the tablet whole with a glass of water, preferably at the same time each day, as directed by your healthcare professional, and follow the prescribed dosage and treatment duration for optimal effectiveness.

Following are the conditions when Lurasidone Hydrochloride 80mg Tablet should not be used:

• Should not be taken if you are allergic to Lurasidone or any other similar antipsychotic medications.
• Not suitable for individuals with a history of heart problems or conditions like irregular heartbeat (prolonged QT interval).
• Contraindicated in patients with severe liver or kidney disease.
• Should not be used in elderly patients with dementia-related psychosis as it may increase the risk of death.
• Not recommended for individuals with a history of low white blood cell count or a bone marrow disorder.
• Avoid using if you have had a recent heart attack or have unstable cardiovascular conditions.
• Contraindicated in patients with a history of breast cancer or other hormone-sensitive cancers.
• Should not be used in individuals with a known sensitivity to lactose as the tablet may contain lactose.

The side effects of Lurasidone Hydrochloride 80mg Tablet may include:

• Dizziness or lightheadedness
• Nausea and vomiting
• Headaches
• Fatigue and drowsiness
• Weight gain
• Restlessness or akathisia
• Indigestion and stomach discomfort
• Muscle stiffness

Following are the precautions and warnings for Lurasidone Hydrochloride 80mg Tablet:

• Do not start or stop taking this medication without consulting your doctor, as sudden discontinuation may lead to withdrawal symptoms.
• This medication may cause drowsiness and dizziness, so patients should avoid driving or operating heavy machinery until they know how it affects them.
• Lurasidone can increase the risk of suicidal thoughts or behavior in young adults; monitor for any changes in behavior or mood.
• Elderly patients may be more sensitive to the side effects; regular monitoring is recommended.
• Inform your doctor if you have a history of heart problems, as this medication may affect heart rhythm.
• Patients with diabetes should monitor their blood sugar levels regularly, as Lurasidone can affect glucose control.
• Do not consume alcohol while taking this medication, as it may increase the risk of certain side effects.

Following are the drug interactions for Lurasidone Hydrochloride 80mg Tablet:

• Lurasidone may interact with other antipsychotic medications, such as aripiprazole or risperidone, leading to increased side effects and potential overdose.
• Concomitant use with strong CYP3A4 inhibitors (e.g., ketoconazole, clarithromycin) can increase lurasidone levels, requiring dose adjustments.
• CYP3A4 inducers (e.g., rifampin, St. John's Wort) may decrease lurasidone effectiveness, necessitating close monitoring.
• Lurasidone can enhance the effects of other central nervous system depressants, including alcohol, opioids, and benzodiazepines, leading to increased sedation and respiratory depression.
• Antihypertensive medications may have their effects reduced by lurasidone, requiring blood pressure monitoring.
• Lurasidone may increase the risk of cardiac arrhythmias when used with other medications known to prolong the QT interval, such as certain antibiotics and antipsychotics.
• Caution is advised when combining Lurasidone with diabetes medications, as it may affect glucose metabolism and require adjustments in antidiabetic treatment.

Following are the food interactions for Lurasidone Hydrochloride 80mg Tablet:

• Grapefruit and grapefruit juice consumption should be avoided as they can increase the levels of Lurasidone in the blood, potentially leading to increased side effects.
• Alcohol intake should be minimized or avoided as it may enhance the sedative effects of Lurasidone, increasing the risk of dizziness and drowsiness.
• Fatty meals can slightly decrease the absorption of Lurasidone, so it is recommended to take the medication on an empty stomach or with a light meal.
• Caffeine-rich foods and beverages might interact with Lurasidone, potentially affecting sleep patterns and increasing anxiety.
• Avoid high-sodium foods as Lurasidone can cause sodium retention, leading to increased blood pressure.
• Consuming potassium-rich foods like bananas and oranges may be beneficial as Lurasidone can cause potassium levels to drop.
• Avoid or limit sugar intake, as Lurasidone may increase blood sugar levels, especially in individuals with diabetes.
• Stay hydrated by drinking plenty of water, as dehydration can increase the risk of side effects like dizziness and lightheadedness.

Lurasidone Hydrochloride 80mg Tablets should be stored in a secure and dry location, preferably in a medicine cabinet or a designated storage area. Keep the tablets in their original container, tightly sealed, to maintain their integrity and protect them from moisture and light. It is crucial to store them at room temperature, avoiding exposure to extreme heat or cold, as temperature fluctuations can impact the medication's effectiveness. Do not store the tablets in the bathroom or kitchen, as these areas can have high humidity and temperature variations. Always check the expiration date, and if the tablets are past their expiry, dispose of them carefully. Proper disposal methods include returning them to a pharmacy or healthcare facility for safe disposal, ensuring they do not contaminate the environment or pose a risk to others. Keep the medication out of children's reach to prevent accidental consumption.

Following are the quick tips for Lurasidone Hydrochloride 80mg Tablet:

• Take the tablet as directed by your doctor. Follow the prescription strictly.
• Swallow the tablet whole with a full glass of water. Do not crush, chew, or break it.
• Lurasidone is usually taken once daily with a meal. Maintain consistency in your dosing routine.
• Avoid alcohol consumption while taking this medication as it may intensify side effects.
• Inform your doctor about all medications you are taking to prevent potential drug interactions.
• Store the tablets at room temperature, away from moisture and heat. Keep them in their original container.
• Do not share your medication with others, even if they have similar symptoms.