LYMEF 400MCG TAB

Dicyclomine primarily exerts its therapeutic effects through its anticholinergic properties. It competitively inhibits the activation of acetylcholine receptors, particularly in the smooth muscles of the gastrointestinal tract. By blocking these receptors, Dicyclomine reduces gastrointestinal motility, relaxes the muscles, and alleviates spasms and associated pain. This mechanism helps in managing conditions like irritable bowel syndrome and other gastrointestinal disorders characterized by excessive intestinal motility and spasms. Mefenamic acid, on the other hand, belongs to the nonsteroidal anti-inflammatory drug (NSAID) class. It acts by inhibiting the enzyme cyclooxygenase (COX), which is responsible for the synthesis of prostaglandins, key mediators of inflammation and pain. By reducing prostaglandin production, Mefenamic acid provides analgesic, anti-inflammatory, and antipyretic effects, helping to alleviate pain, inflammation, and fever associated with various conditions.

Anticholinergic, Non-steroidal anti-inflammatory drug (NSAID)

Tablet

The following are the uses of Dicyclomine, Mefnamic Acid Tablet:

• Used for relieving painful muscle spasms, especially in the stomach and intestines.
• Used to treat gastrointestinal issues like irritable bowel syndrome (IBS) and functional bowel disorders.
• Used for reducing inflammation and pain associated with conditions like arthritis and menstrual cramps.
• Used to manage symptoms of colic in infants.
• Used to alleviate abdominal pain and discomfort.
• Used for providing relief from muscle stiffness and pain.
• Used as a short-term treatment for gastrointestinal and menstrual pain.

In the case of an overdose of Dicyclomine and Mefenamic Acid Tablets, symptoms may include severe drowsiness, confusion, seizures, and gastrointestinal issues such as nausea, vomiting, and diarrhea. Prompt medical attention is necessary, and healthcare professionals should be informed about the specific medications involved. Treatment may involve supportive care, gastric lavage, and administering activated charcoal to prevent further absorption of the drugs. It is crucial to seek medical help immediately if an overdose is suspected.

In the case of a missed dose of Dicyclomine, it is generally recommended to take the missed dose as soon as you remember, provided it is not too close to the time of your next scheduled dose. If it is almost time for your next dose, skip the missed one and continue with your regular dosing schedule. For Mefenamic Acid Tablet, if you miss a dose, take it as soon as you remember, but if it is near the time of the next dose, skip the missed dose and resume your regular dosing schedule. It is important to not double the dose to make up for a missed one.

To take the Dicyclomine, Mefenamic Acid Tablet, swallow the tablet whole with a full glass of water, preferably with or after a meal, as directed by your healthcare professional.

Here are the conditions or situations when Dicyclomine, Mefenamic Acid Tablet should not be taken:

• Avoid if you are allergic to Dicyclomine, Mefenamic Acid, or any other similar medications.
• Do not use if you have a history of gastrointestinal bleeding or perforation.
• Contraindicated in individuals with kidney disease or severe kidney impairment.
• Should not be taken if you have a history of heart disease, high blood pressure, or stroke.
• Not suitable for patients with a history of asthma or other respiratory disorders.
• Avoid if you have a blockage or obstruction in your intestines.
• Do not use if you have a known blood disorder or bleeding disorder.
• Contraindicated during the last trimester of pregnancy.
• Should not be used if you have a history of liver problems or jaundice after taking medications.
• Not recommended for individuals with a history of seizures or epilepsy.

The side effects of Dicyclomine, Mefenamic Acid Tablet may include:

• Dizziness
• Blurred vision
• Dry mouth
• Nausea and vomiting
• Constipation or diarrhea
• Stomach pain or discomfort
• Skin rashes or itching
• Drowsiness or fatigue

Following are the precautions and warnings for Dicyclomine, Mefenamic Acid Tablet:

• This medication should be used with caution in patients with gastrointestinal conditions like ulcerative colitis, gastrointestinal bleeding, or liver disease, as it may aggravate these conditions.
• Patients with a history of heart disease, hypertension, or stroke should exercise caution, as this medication may increase the risk of cardiovascular events.
• It is important to avoid excessive use of this medication, as it may lead to kidney damage or failure, especially in patients with pre-existing kidney issues.
• Dicyclomine may cause blurred vision and dizziness, so patients should be cautious when performing tasks requiring clear vision and alertness.
• Not recommended for individuals with a known allergy to Dicyclomine or Mefenamic Acid or any of its components.
• Should be used with caution in elderly patients, as they may be more susceptible to side effects.
• Women who are pregnant or breastfeeding should consult their doctor before taking this medication, as it may pose risks to the fetus or infant.

Following are the drug interactions for Dicyclomine, Mefenamic Acid Tablet:

• Alcohol and other central nervous system depressants may increase the risk of drowsiness and dizziness when taken with Dicyclomine.
• Antacids containing magnesium or aluminum can reduce the absorption of Mefenamic Acid, so it is advised to take these medications at least 2 hours apart.
• Nonsteroidal anti-inflammatory drugs (NSAIDs) similar to Mefenamic Acid may increase the risk of gastrointestinal bleeding and kidney problems when used together.
• Probenecid, a medication used to treat gout, can increase the blood levels of Mefenamic Acid, potentially leading to increased side effects.
• Dicyclomine may interfere with the absorption of other medications, particularly those that require an acidic stomach environment for optimal absorption.
• Lithium levels may be increased when used with Dicyclomine, requiring close monitoring of lithium levels.
• The use of Mefenamic Acid with angiotensin-converting enzyme (ACE) inhibitors may decrease the effectiveness of the latter in reducing blood pressure.

Following are the food interactions for Dicyclomine, Mefenamic Acid Tablet:

• Alcohol consumption should be avoided as it can increase the risk of gastrointestinal bleeding and liver damage when combined with Mefenamic Acid.
• Grapefruit and grapefruit juice should be consumed with caution as they may interfere with the metabolism of Dicyclomine, potentially leading to increased side effects.
• High-fat meals can delay the absorption of Mefenamic Acid, possibly reducing its effectiveness. It is recommended to take the medication on an empty stomach.
• Dairy products like milk and cheese should be consumed with care as they may decrease the absorption of Mefenamic Acid, affecting its efficacy.
• Caffeine intake should be monitored as it can increase the likelihood of experiencing side effects such as nervousness, insomnia, and rapid heartbeat.
• Spicy foods might irritate the stomach and exacerbate gastrointestinal side effects when taking Mefenamic Acid.
• A balanced diet rich in fiber and fluids is advisable to minimize the risk of constipation, a potential side effect of Dicyclomine.
• Avoid excessive salt intake as Mefenamic Acid may lead to fluid retention, which can be aggravated by high sodium levels.

Dicyclomine, Mefenamic Acid Tablets should be stored in a secure and dry location, preferably in a medicine cabinet or a designated storage area, ensuring they are out of reach of children and pets. Maintain a consistent room temperature, avoiding exposure to direct sunlight, excessive heat, or moisture to prevent degradation. Always keep the tablets in their original container, tightly sealed, to maintain their integrity and effectiveness. It is crucial not to flush or pour the medication down the drain; instead, consult your pharmacist or healthcare provider for appropriate disposal methods to minimize environmental impact. Regularly check the expiration date, and properly discard any expired or unused tablets according to local pharmaceutical waste management guidelines. By following these storage and disposal practices, you can ensure the safety and efficacy of the medication while adhering to responsible environmental practices.

Following are the quick tips for Dicyclomine and Mefenamic Acid Tablet:

• Consult your doctor for the correct dosage and usage instructions.
• Take the tablet with a full glass of water, preferably with food or after meals.
• Do not crush, chew, or break the tablet; swallow it whole.
• Avoid taking antacids or dairy products within 1 hour of taking the tablet.
• Inform your doctor if you have any gastrointestinal or kidney-related medical conditions.
• Do not take this medication if you are pregnant, breastfeeding, or trying to conceive.
• Store the tablets in a cool, dry place, away from direct sunlight and moisture.