Macpram (10mg) 14 Tablets

Macpram (10mg) 14 Tablets

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  • Manufacturer McOLSON Research Laboratories (Pvt.) Ltd.
  • Generic Name Escitalopram

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Product Information

  • Description
  • Ingredients
  • Drug Class
  • Dosage Form
  • Uses
  • Dosage
  • In case of Overdose
  • Missed Dose
  • How To Use
  • When Not to Use
  • Side Effects
  • Precautions & Warnings
  • Drug Interactions
  • Food Interactions
  • Storage/Disposal
  • Description

    Escitalopram is a type of antidepressant known as a selective serotonin reuptake inhibitor (SSRI). Serotonin is a neurotransmitter that helps to regulate emotions and feelings of well-being, and SSRIs increase the amount of serotonin available in the brain. This increase in serotonin helps to improve mood, energy level, and interest in things, providing an individual with therapeutic relief from depressive symptoms. One of the key mechanisms behind Escitalopram's efficacy is its ability to block the reuptake of serotonin. Typically, once a nerve cell releases serotonin, it is reabsorbed back into the cell, a process known as reuptake. By blocking this process, Escitalopram ensures that more serotonin remains in the brain, providing additional mood-enhancing effects. Given the variable nature of depression and individual brain chemistry, it's crucial to appreciate that Escitalopram may not work identically for every person. While it typically takes several weeks of consistent use to feel the full effects of Escitalopram, some people may experience benefits sooner than others, and individual responses vary. It is always advised to consult a medical professional for guidance on Escitalopram or any concerns you may have.

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  • Ingredients

    Escitalopram
  • Drug Class

    Selective Serotonin Reuptake Inhibitors (Ssris)

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  • Dosage Form

    Tablet

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  • Uses

    Unveiling its multifaceted uses and transformative applications as follows:

    • Escitalopram is an SSRI that regulates serotonin to treat depression and anxiety.
    • It takes several weeks to notice the effects of treatment and stopping escitalopram may result in withdrawal symptoms.

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  • Dosage

    Tailoring Treatment for Optimal Health, Prescribed Medication Dosage is:

    • Depression - 10mg is the usual dosage but may go up to 20mg if required
    • Anxiety - 10mg is the starting point for adults, an increase to 20mg is not necessarily required
    • Enuresis - in adults, the starting dose is usually 10mg daily
    • Musculoskeletal pain - 10mg is the starting point but dose escalation up to 40mg daily has been used

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  • In case of Overdose

    Escitalopram is a medication that is primarily used to treat anxiety and depression. This medication comes in tablet form and is usually ingested orally, often at a dosage of anywhere from 10-20mg daily. While this medication can be quite effective in treating the symptoms of anxiety and depression, an overdose can be dangerous.If you take too much escitalopram, it can lead to several severe side effects such as dizziness, confusion, agitation, sweating, a fast heart rate, tremors, seizures, flushed skin, constipation, and dry mouth. If you believe you have overdosed on escitalopram, it is crucial that you seek medical attention right away.Typically, treatment for such an overdose would include supportive care. This involves monitoring the heart and lungs, as well as dealing with any other symptoms that may arise. In more severe cases, you might need detoxification through dialysis or another method.

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  • Missed Dose

    Maintaining a regular medication schedule is crucial, especially when taking escitalopram. Nevertheless, if a dose is missed, it is safe to take the missed dose shortly after noticing the omission. If it is almost time for the next scheduled dose, it is better to skip the missed dose and revert to the regular schedule to avoid the possibility of an overdose. However, if you experience confusion or abnormal symptoms, it is imperative to seek professional assistance immediately.

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  • How To Use

    Before starting Escitalopram, be sure to read the medication guide provided by your pharmacist. This guide will help you understand the uses, risks, and benefits of the medication, or you can also consult your doctor or pharmacist with any questions or concerns. Escitalopram should be taken exactly as prescribed by your healthcare provider. It is typically taken once daily, either in the morning or evening, with or without food. Swallow the tablet whole with a glass of water—do not crush or chew it. Make sure to take the medication at the same time each day to maintain an even level in your bloodstream. Continue taking it regularly, even if you feel well, as it may take a few weeks to notice the full benefits. If you miss a dose, take it as soon as you remember, unless it is close to your next scheduled dose. Do not double up on doses.

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  • When Not to Use

    Discerning instances where this medication may not be appropriate:

    • You should not take Escitalopram (10mg) if you are allergic to Escitalopram or any of its ingredients.
    • Do not take Escitalopram if you are taking a monoamine oxidase inhibitor (MAOI) such as phenelzine or isocarboxazid, or have taken one within the last 14 days.
    • Avoid taking Escitalopram if you have a history of seizures or epilepsy.
    • The drug is not suitable for you if you have bleeding problems or take blood thinners.
    • Take caution and consult your physician if you have glaucoma or cataracts.
    • Talk to your doctor or pharmacist if you have liver or kidney disease.
    • Escitalopram is categorized as Category D drug by the FDA as to its safety for use during pregnancy. This category demonstrates potential risk to the fetus, and therefore, should only be taken if the physician deems its potential benefits outweigh the risks.
    • Escitalopram is excreted in breast milk and can induce drowsiness and sedation in the nursing infant. Thus, it is advised to exercise caution and inform your physician if you are pregnant, intend to conceive, or are breastfeeding.
    • Interactions and side effects can vary from person to person, and that you should always consult with a medical professional or pharmacist before starting any new medication.
    • It is advisable to only stop or start a drug like Escitalopram under medical supervision.

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  • Side Effects

    Unraveling the side effects lurking behind this medications are as follows:

    • Dry mouth
    • Increased risk of bleeding and bruising
    • Low libido
    • Mood swings & depression
    • Constipation
    • Agitation
    • Sweating
    • Dizziness

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  • Precautions & Warnings

    The warnings and precautions associated with Escitalopram are:

    • Patient with history of seizure disorder or condition predisposing to seizures (e.g. brain damage, alcoholism), controlled epilepsy.
    • History of mania/hypomania or suicide-related events, significant degree of suicidal ideation.
    • Diabetes, known bleeding tendencies, bradycardia, recent acute MI, uncompensated heart failure, electrolyte disturbances (e.g. hypokalaemia, hypomagnesaemia), angle-closure glaucoma or history of glaucoma, metabolic disease.
    • Avoid abrupt withdrawal.
    • Avoid use in patients with unstable epilepsy.
    • Concomitant electroconvulsive therapy.
    • CYP2C19 ultrarapid, intermediate, or poor metabolisers.
    • Hepatic and severe renal (CrCl <30 mL/min) impairment.
    • Children and elderly.

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  • Drug Interactions

    The drug interactions with escitalopram include:

    • MAO Inhibitors – Concurrent use with monoamine oxidase inhibitors (MAOIs) can lead to serotonin syndrome, a potentially life-threatening condition.
    • Other Antidepressants – Combining with other antidepressants, especially SSRIs or SNRIs, can increase the risk of serotonin syndrome.
    • Anticoagulants and Antiplatelet Agents – Escitalopram can increase the risk of bleeding when used with anticoagulants or antiplatelet drugs such as warfarin or aspirin.
    • NSAIDs – Non-steroidal anti-inflammatory drugs (NSAIDs) may increase the risk of gastrointestinal bleeding when used with escitalopram.
    • CYP3A4 Inhibitors – Escitalopram metabolism can be affected by CYP3A4 inhibitors like ketoconazole, leading to increased escitalopram levels and potential side effects.
    • CYP2C19 Inhibitors – Inhibitors of CYP2C19, such as omeprazole, can increase escitalopram levels, potentially leading to an increased risk of side effects.
    • Lithium – Combining escitalopram with lithium may increase the risk of serotonin syndrome and require careful monitoring.
    • Alcohol – Escitalopram can enhance the sedative effects of alcohol, leading to increased drowsiness and impaired coordination.
    • St. John's Wort – This herbal supplement can interact with escitalopram, potentially leading to serotonin syndrome and reducing the effectiveness of escitalopram.
    • Tramadol – The combination with tramadol can increase the risk of serotonin syndrome and requires careful monitoring.

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  • Food Interactions

    The food interactions that should be considered before using Escitalopram are:

    • Alcohol can increase the nervous system side effects of the product such as dizziness drowsiness and difficulty concentrating.
    • Avoid or limit the use of alcohol while being treated with the product.

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  • Storage/Disposal

    Escitalopram is an antidepressant that falls into the category of serotonin-norepinephrine reuptake inhibitors (SNRIs), and it is used to treat depression and generalized anxiety disorder (GAD). It is important to follow guidelines for proper storage of Escitalopram in order to ensure its effectiveness and safety. The medication should be stored in a cool, dry place, away from direct heat and sunlight. The ideal temperature range for storing Escitalopram is between 68°F and 77°F (20°C and 25°C), and it should not be kept in places where the temperature rises above 86°F (30°C) as it can degrade under such conditions. Hence, it is best to avoid storing it in locations such as cars, bathrooms, or any area where it may become hot. It is also necessary to keep the medication in its original container or packaging, and to always keep it securely closed to prevent moisture and light from affecting the drug's effectiveness. Moreover, Escitalopram should be kept out of reach of children, pets, and other individuals who might accidentally take it. It is crucial to follow these guidelines to ensure that Escitalopram is efficient and safe for use. If you have any questions or concerns about storing Escitalopram, it is recommended to consult your doctor or pharmacist for more information.

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