MACTIFEN CAP

Ketotifen, the active ingredient in Ketotifen tablets, primarily acts as a selective histamine H1-receptor antagonist, effectively blocking the effects of histamine in various tissues. Its mechanism of action involves binding to H1-receptors, thereby preventing histamine-induced responses. This action helps to stabilize mast cells, reducing the release of inflammatory mediators such as histamine, leukotrienes, and prostaglandins. By inhibiting the activation of mast cells, Ketotifen suppresses allergic reactions and exhibits anti-inflammatory properties. Additionally, Ketotifen has been shown to have some affinity for other receptors, including H2 and H3 histamine receptors, and may exert its effects through these pathways as well, contributing to its overall therapeutic action.

Ketotifen

Antihistamine/mast cell stabilizer.

Tablet

The following are the uses of Ketotifen Tablet:

• Used for relieving allergic symptoms like itching, sneezing, and runny nose.
• Used for treating allergic conditions such as hay fever and hives.
• Used to prevent asthma attacks triggered by allergens.
• Used to reduce inflammation in the eyes due to allergies.
• Used for managing chronic urticaria (long-term hives).
• Used to alleviate symptoms of allergic conjunctivitis.
• Used to enhance the effectiveness of other allergy medications.
• Used as a preventive measure for seasonal allergy symptoms.

Tailoring Treatment for Optimal Health, Prescribed Medication Dosage is:

• Ketotifen 1mg is used to treat asthma, allergic rhinitis, urticaria, and conjunctivitis.
• The recommended dosage depends on the condition being treated.
• Asthma- Start with 1 tablet of Ketotifen 1mg daily and increase to a maximum of 4 tablets daily if needed.
• Allergic Rhinitis- Start with 1 tablet of Ketotifen 1mg daily and increase to a maximum of 2 tablets daily if needed.
• Urticaria- Start with 1 tablet of Ketotifen 1mg daily and increase to a maximum of 3 tablets daily if needed.
• Conjunctivitis- Start with 1 tablet of Ketotifen 1mg daily and increase to a maximum of 2 tablets daily if needed.

In the case of an overdose of Ketotifen tablets, it is important to recognize the potential symptoms and take appropriate action. Common signs may include severe drowsiness, difficulty breathing, and increased heart rate. If an overdose is suspected, immediate medical advice should be sought. Promptly contact a healthcare professional or a poison control center for guidance on the necessary steps to address the overdose and ensure the individual's safety.

In the case of a missed dose of Ketotifen Tablet, it is important to take the medication as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one, as this may increase the risk of side effects. If you miss multiple doses, contact your healthcare provider for guidance on how to safely resume your medication regimen. It is advisable to set reminders or use a pill organizer to help you remember to take your medication as prescribed.

To take Ketotifen Tablets, place the tablet on your tongue and allow it to dissolve, preferably without chewing, and can be taken with or without food, following the dosage instructions provided by your healthcare professional, typically once or twice a day, depending on your specific condition and your doctor's recommendation.

Following are the conditions or circumstances when Ketotifen Tablet should not be used:

• Must not be used in patients with a known allergy or hypersensitivity to Ketotifen or any of its excipients.
• Not suitable for individuals with a history of narrow-angle glaucoma.
• Contraindicated in patients with severe liver impairment.
• Should not be administered to children under 3 years of age due to potential risks.
• Avoid using it if you have a history of asthma exacerbation triggered by aspirin or other non-steroidal anti-inflammatory drugs (NSAIDs).
• Not recommended for individuals with a history of porphyria, a disorder affecting the production of heme in the body.
• Do not use if you are breastfeeding, as Ketotifen may pass into breast milk.
• Should not be used in patients with a history of allergic reactions to other antihistamines.

The side effects of Ketotifen Tablet may include:

• Drowsiness or fatigue
• Dry mouth
• Upset stomach or nausea
• Diarrhea
• Dizziness
• Skin rash or itching
• Increased appetite and weight gain
• Difficulty concentrating

Following are the precautions and warnings for Ketotifen Tablet:

• Not suitable for individuals with a known allergy to Ketotifen or any of its ingredients.
• Patients with a history of liver or kidney disease should use with caution and under medical supervision, as it may require dosage adjustments.
• Ketotifen can cause drowsiness and dizziness, so activities requiring alertness, such as driving or operating heavy machinery, should be avoided until the individual knows how the medication affects them.
• Alcohol consumption should be avoided as it can increase the risk of side effects and drowsiness.
• Elderly patients may be more sensitive to the side effects of Ketotifen, so monitoring for adverse reactions is essential.
• Children's use should be under medical supervision, as dosage adjustments are necessary based on age and weight.
• Consult a healthcare professional if you are pregnant, planning to become pregnant, or breastfeeding, as Ketotifen's safety during these periods is not fully established.

Following are the drug interactions for Ketotifen Tablet:

• Avoid using with alcohol, as it may increase drowsiness and impair alertness.
• Ketotifen can interact with certain antihistamines, such as diphenhydramine, potentially causing excessive sedation.
• Concomitant use with central nervous system (CNS) depressants like benzodiazepines or barbiturates can enhance their effects and may lead to respiratory depression.
• Antifungal medications like ketoconazole can increase Ketotifen blood levels, leading to increased side effects.
• It may decrease the effectiveness of certain vaccines, so consult a doctor before getting vaccinated.
• Some antibiotics, such as erythromycin, can affect Ketotifen metabolism, potentially altering its effectiveness.
• Caution is advised when using with other medications that affect the heart rate, as Ketotifen may cause bradycardia.

Following are the food interactions to be aware of when taking Ketotifen Tablets:

• Ketotifen may cause an increase in appetite, leading to potential weight gain. Monitor your food intake and maintain a balanced diet.
• Grapefruit juice should be avoided as it can interfere with the metabolism of Ketotifen, potentially increasing its levels in the body and the risk of side effects.
• Alcohol consumption should be limited as it can enhance the sedative effects of Ketotifen, causing increased drowsiness and dizziness.
• Avoid high-fat meals as they can slow down the absorption of Ketotifen, potentially reducing its effectiveness.
• Caffeine intake should be monitored as it may counteract the sedative effects of Ketotifen, making sleep disturbances more likely.
• Maintain a consistent fluid intake to prevent dehydration, especially if you experience increased thirst as a side effect.
• Consult your healthcare provider for specific dietary recommendations, especially if you have underlying health conditions that require dietary restrictions.

Ketotifen Tablets should be stored in a cool and dry place, preferably at room temperature, away from direct sunlight and moisture. It is crucial to keep the tablets in their original container, ensuring the cap is tightly sealed to maintain their integrity and prevent contamination. Avoid storing them in bathrooms or kitchens, as temperature fluctuations and humidity can impact their effectiveness. Regularly check the expiration date, and if the tablets have passed their expiry, do not use them and dispose of them appropriately. When disposing of unused or expired tablets, do not flush them or throw them into the trash; instead, consult a pharmacist or local waste management guidelines for safe disposal methods. Keep the medication out of children's reach to prevent accidental consumption.

Following are the quick tips for Ketotifen Tablet:

• Consult your doctor before starting the medication for personalized advice.
• Take the tablet as directed by your physician, typically once or twice daily.
• Consume the tablet with a full glass of water for better absorption.
• Maintain a consistent schedule for taking the medication, preferably at the same time each day.
• Do not crush or chew the tablet; swallow it whole for optimal effectiveness.
• Inform your doctor about any allergies or medical conditions before taking Ketotifen.
• Store the medication at room temperature, away from moisture and direct sunlight.

It is important to consult a healthcare professional if you are taking Ketotifen 1mg to undergo any lab tests. Your specific health condition and the purpose of the medication may determine which lab tests are required. Generally, ketotifen 1mg may require various lab tests, which include liver function tests, blood pressure monitoring, eye exams, and allergy tests. Ketotifen may impact liver function, so your healthcare provider may recommend regular liver tests to monitor liver enzyme levels and ensure that the medication is not causing liver damage. Depending on your health condition, blood pressure monitoring may be required, especially if you are prone to blood pressure issues; the doctor may monitor your blood pressure to ensure it remains within a safe range. If you are taking ketotifen 1mg to relieve eye conditions associated with itchy or watery eyes, regular eye exams may be recommended to assess the progression of the condition and determine the medication's effectiveness. Allergy tests may be required if you are taking ketotifen 1mg for allergy treatment, and your doctor may recommend periodic allergy tests to evaluate your response to allergens and adjust your treatment plan. It is important to remember that the lab tests required may vary from person to person, and consulting your doctor or healthcare provider is essential before taking any lab tests while on ketotifen 1mg. Furthermore, it is crucial to inform your healthcare provider about all other medications you may be taking during the treatment with ketotifen 1mg.