Magura (0.5mg) 50 Tablets

Magura (0.5mg) 50 Tablets

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  • Manufacturer SAMI Pharmaceuticals (Pvt.) Ltd.
  • Generic Name

    Clonazepam 0.5mg

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Rs. 44.6
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Product Information

  • Description
  • Ingredients
  • Drug Class
  • Dosage Form
  • Uses
  • Dosage
  • In case of Overdose
  • Missed Dose
  • How To Use
  • When Not to Use
  • Side Effects
  • Precautions & Warnings
  • Drug Interactions
  • Food Interactions
  • Storage/Disposal
  • Control Drug
  • Quick Tips, if any
  • Description

    Clonazepam 0.5mg tablets exert their therapeutic effects primarily through positive allosteric modulation of the gamma-aminobutyric acid (GABA) type A receptors in the central nervous system. By binding to specific sites on these receptors, clonazepam enhances the inhibitory effects of GABA, a neurotransmitter that plays a crucial role in reducing neuronal excitability. This modulation leads to an increase in GABAergic neurotransmission, resulting in sedative, hypnotic, anxiolytic, anticonvulsant, and muscle relaxant properties. The potentiation of GABA's inhibitory actions helps to stabilize neuronal membranes, reduce excessive neuronal firing, and mitigate the abnormal electrical activity associated with various conditions, thereby providing therapeutic benefits in the management of anxiety disorders, seizure control, and certain movement disorders.

  • Ingredients

    Clonazepam 0.5mg

  • Drug Class

    Benzodiazepine

  • Dosage Form

    Tablet

  • Uses

    The following are the uses of Clonazepam 0.5mg Tablet:

    • Used for managing and treating panic attacks and other severe anxiety disorders.
    • Used to treat certain types of seizures, effectively controlling abnormal electrical activity in the brain.
    • Used for short-term relief from anxiety symptoms, providing a calming effect.
    • Helps in the treatment of social phobia, reducing fear and improving social interactions.
    • Effective in managing specific movement disorders, such as akathisia.
    • Used as a second-line treatment for bipolar disorder, particularly during acute mania.
    • Can be used as a sedative to induce sleep and treat insomnia.
    • May be utilized in the treatment of restless leg syndrome, providing relief from discomfort.
  • Dosage

    To be taken strictly on the prescription of a doctor for the designated time in correct amounts.

  • In case of Overdose

    In the case of an overdose of Clonazepam 0.5mg tablets, individuals may experience symptoms such as extreme drowsiness, confusion, and impaired coordination. They might also exhibit respiratory depression, with breathing becoming slow and shallow. In severe cases, an overdose can lead to a coma, where the person loses consciousness and responsiveness. It is important to seek medical assistance promptly if an overdose is suspected, as timely intervention can prevent potential complications and ensure appropriate treatment.

  • Missed Dose

    In the case of a missed dose of Clonazepam 0.5mg Tablet, it is important to take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one. If you miss multiple doses, contact your healthcare provider for guidance on how to safely adjust your medication regimen. It is generally recommended to take the missed dose within a few hours of the intended time to maintain therapeutic levels of the medication.

  • How To Use

    To take Clonazepam 0.5mg Tablet, place the tablet in your mouth and swallow it whole with a glass of water, following the dosage instructions provided by your healthcare professional, typically taken two to three times a day or as directed.

  • When Not to Use

    Following are the conditions or circumstances when Clonazepam 0.5mg Tablet should not be taken:

    • Avoid if you have a known allergy or hypersensitivity to Clonazepam or other benzodiazepines.
    • Do not use if you have narrow-angle glaucoma.
    • Contraindicated in patients with severe liver impairment or liver disease.
    • Should not be used if you have severe respiratory depression or breathing problems.
    • Avoid if you have a history of substance abuse or dependence.
    • Not recommended for patients with myasthenia gravis.
    • Do not take if you have a history of depression or suicidal thoughts.
    • Contraindicated in patients with sleep apnea syndrome.
    • Should be avoided if you have acute narrow-angle glaucoma.
    • Not suitable for individuals with certain blood disorders (e.g., porphyria).
  • Side Effects

    The side effects of Clonazepam 0.5mg Tablet may include:

    • Drowsiness or sedation
    • Impaired coordination and balance
    • Confusion or disorientation
    • Slurred speech
    • Memory problems
    • Fatigue and weakness
    • Increased saliva production
    • Changes in appetite and weight
  • Precautions & Warnings

    Following are the precautions and warnings for Clonazepam 0.5mg Tablet:

    • Do not use if you are allergic to Clonazepam or any other benzodiazepines.
    • This medication may cause drowsiness and impair your ability to drive or operate machinery; avoid such activities until you know how the medication affects you.
    • Inform your doctor if you have a history of liver or kidney disease, as dosage adjustments may be necessary.
    • Elderly patients should use with caution, as they may be more sensitive to the effects and side effects of the medication.
    • Do not consume alcohol while taking Clonazepam, as it can increase the sedative effects and impair your ability to function.
    • Pregnant and breastfeeding women should consult their doctor before taking this medication, as it may cause harm to the fetus or infant.
    • Do not abruptly stop taking Clonazepam, as it may lead to withdrawal symptoms; consult your doctor for a proper tapering schedule.
  • Drug Interactions

    Following are the drug interactions for Clonazepam 0.5mg Tablet:

    • Alcohol and other central nervous system depressants like opioids or barbiturates can increase the sedative effects of Clonazepam, leading to severe drowsiness and difficulty breathing.
    • Combining with certain antidepressants (e.g., SSRIs, MAOIs) may result in increased sedation, respiratory depression, and potential serotonin syndrome.
    • The effects of anticonvulsant medications may be altered, requiring close monitoring of blood levels.
    • Drugs that inhibit liver enzymes (e.g., certain antifungal medications) can increase Clonazepam levels, leading to enhanced side effects.
    • Clonazepam may increase the concentration of digoxin, a heart medication, requiring careful monitoring.
    • Blood pressure medications, especially calcium channel blockers, can have their effects potentiated, leading to excessive hypotension.
    • Medications that prolong the QT interval, such as certain antiarrhythmic drugs, should be used cautiously with Clonazepam due to potential cardiac risks.
  • Food Interactions

    Following are the food interactions for Clonazepam 0.5mg Tablet:

    • Avoid alcohol consumption while taking this medication as it can enhance the sedative effects and increase the risk of dizziness and drowsiness.
    • Grapefruit and grapefruit juice should be consumed with caution as they can affect the metabolism of Clonazepam, leading to increased drug levels in the blood and potential side effects.
    • Caffeine intake should be monitored as it can interfere with the calming effects of Clonazepam, reducing its effectiveness.
    • Fatty or greasy foods may slow down the absorption of Clonazepam, potentially affecting its onset of action.
    • Avoid eating large meals immediately after taking Clonazepam, as it may affect the rate at which the medication is absorbed.
    • Some herbal supplements like St. John's Wort may interact with Clonazepam, potentially reducing its effectiveness.
    • Always inform your healthcare provider about your dietary habits and any supplements you take to ensure safe and effective use of Clonazepam.
    • No specific food restrictions are necessary, but maintaining a balanced diet is advisable for overall health.
  • Storage/Disposal

    Clonazepam 0.5mg Tablets should be stored in a secure and dry location, preferably in a medicine cabinet or a designated storage area, ensuring it remains out of reach of children and pets. It is recommended to keep the medication in its original container, tightly sealed, to maintain its integrity and prevent contamination. Avoid exposing the tablets to excessive heat, moisture, or direct sunlight, as these conditions can degrade the medication. Always check the expiration date on the packaging, and do not use the tablets if they appear damaged or discolored. When disposing of unused or expired Clonazepam tablets, do not flush them down the toilet or throw them into the garbage. Instead, consult your pharmacist or local waste management authority for guidance on proper pharmaceutical disposal methods to ensure environmental safety.

  • Control Drug

    Yes

  • Quick Tips, if any

    Following are the quick tips for Clonazepam 0.5mg Tablet:

    • Take the tablet as directed by your doctor, usually 2-3 times daily.
    • Swallow the tablet whole with water; do not crush or chew.
    • Maintain a consistent daily routine for taking the medication.
    • Avoid alcohol and other CNS depressants while on this medication.
    • Do not drive or operate machinery until you know how this medication affects you.
    • Inform your doctor about all medications you're taking to prevent potential interactions.
    • Store the tablets at room temperature, away from moisture and light.

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