Maiorad (100mg) 30 Tablets

Tiropramide, a medication primarily used for its gastrointestinal effects, acts on the gut by modulating the release of acetylcholine from cholinergic nerve endings. Its primary mechanism involves blocking the presynaptic calcium channels, thereby reducing the amount of acetylcholine released into the synaptic cleft. This action is particularly significant in the gastrointestinal tract, where it helps to decrease intestinal motility and secretions, leading to a reduction in diarrhea and associated symptoms. By inhibiting the excessive release of acetylcholine, Tiropramide effectively calms overactive gastrointestinal muscles and glands, providing relief from various gastrointestinal disorders characterized by increased motility and secretion.

Antispasmodic

Tablet

The following are the uses of Tiropramide Tablet:

• Used for treating abdominal pain and discomfort associated with various gastrointestinal disorders.
• Used for relieving symptoms of irritable bowel syndrome, such as bloating, gas, and diarrhea.
• Used for reducing muscle spasms in the intestinal tract, providing relief from cramping pain.
• Used for managing functional gastrointestinal disorders, improving overall digestive comfort.
• Used for alleviating pain and discomfort during endoscopic procedures, ensuring patient relaxation.
• Used for short-term management of acute gastrointestinal symptoms, offering quick relief.
• Used for normalizing gastrointestinal motility, helping regulate bowel movements.
• Used for supporting overall gut health and well-being, promoting a healthy digestive system.

In the case of an overdose of Tiropramide Tablets, it is important to recognize the potential severity of the situation. Symptoms may include severe drowsiness, confusion, and respiratory depression. If an overdose is suspected, seek medical assistance immediately. Prompt action can help mitigate the risks associated with an overdose, and medical professionals will be able to provide the necessary care and support to manage the situation effectively. Do not delay seeking help as quick response is vital.

In the case of a missed dose of Tiropramide Tablet, it is important to take the medication as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one, as this may increase the risk of side effects. If you miss multiple doses, consult your healthcare professional for advice on how to get back on track with your medication regimen. Remember, maintaining a consistent dosing schedule is crucial for the effectiveness of the treatment.

To take Tiropramide Tablets, swallow the tablet whole with a glass of water, preferably during or after a meal, once or twice a day as directed by your doctor, and do not crush, chew, or break the tablet.

Here are the conditions or situations when Tiropramide Tablet should not be taken:

• Avoid using Tiropramide if you have a known allergy or hypersensitivity to Tiropramide or any of its excipients.
• Do not take this medication if you have severe liver or kidney disease, as it may worsen your condition.
• Contraindicated in patients with a history of epilepsy or seizures, as it may lower the seizure threshold.
• Should not be used in patients with gastrointestinal obstruction or severe constipation, as it can cause further blockage.
• Not suitable for individuals with rare hereditary problems of galactose intolerance, the Lapp lactase deficiency, or glucose-galactose malabsorption.
• Do not administer to children under 12 years of age due to a lack of safety and efficacy data.
• Tiropramide is not recommended for use during pregnancy or breastfeeding, as its safety is not established.
• Avoid if you have a history of porphyria, a group of disorders affecting the skin and nervous system.
• Do not take this medication if you have a history of drug abuse or addiction, as it may have potential for dependence.
• Should not be used in patients with severe respiratory depression or asthma, as it can worsen breathing difficulties.

The side effects of Tiropramide Tablet may include:

• Dizziness
• Fatigue
• Dry mouth
• Constipation
• Nausea and vomiting
• Loss of appetite
• Blurred vision
• Difficulty urinating

Following are the precautions and warnings for Tiropramide Tablet:

• Tiropramide should not be taken if you have a known allergy to its active ingredient or any other components in the tablet.
• Patients with a history of liver or kidney disease should exercise caution and consult a healthcare professional before use, as Tiropramide may require dosage adjustments in such cases.
• This medication may cause drowsiness or dizziness, so patients should avoid driving, operating heavy machinery, or engaging in activities that require mental alertness until they know how the medication affects them.
• Alcohol consumption should be avoided while taking Tiropramide, as it may enhance the sedative effects and increase the risk of accidents.
• If you have a history of gastrointestinal disorders, such as gastrointestinal obstruction or severe constipation, consult your doctor before taking this medication.
• Tiropramide should be used with caution in elderly patients, as they may be more sensitive to its side effects.
• Pregnant and breastfeeding women should consult their doctor before using Tiropramide, as the potential risks and benefits should be carefully considered.
• Keep Tiropramide out of the reach of children and pets, and store it in a safe and secure location.

Following are the drug interactions for Tiropramide Tablet:

• Alcohol may enhance the sedative effects of Tiropramide, leading to increased drowsiness and impaired coordination.
• Tiropramide can interact with opioids, intensifying respiratory depression and sedation. Close monitoring is required.
• Anticonvulsants like phenytoin or carbamazepine may decrease the effectiveness of Tiropramide by increasing its metabolism.
• Anticoagulants, Tiropramide might affect blood clotting, so monitoring is necessary when used with warfarin or similar drugs.
• Antidepressants (e.g., SSRIs, tricyclics) can have additive effects on serotonin levels, potentially leading to serotonin syndrome.
• Central nervous system (CNS) depressants (e.g., benzodiazepines, barbiturates) may potentiate the sedative effects of Tiropramide.
• Tiropramide may increase the risk of cardiac arrhythmias when taken with certain antiarrhythmic medications.
• The effectiveness of hormonal contraceptives may be reduced by Tiropramide, requiring alternative birth control methods.

Following are the food interactions for Tiropramide Tablet:

• Avoid consuming alcohol with Tiropramide as it may increase the risk of dizziness, drowsiness, and other central nervous system side effects.
• Grapefruit and grapefruit juice should be consumed with caution as they may affect the metabolism of Tiropramide, leading to increased levels in the body and potential side effects.
• High-fat meals can delay the absorption of Tiropramide, potentially reducing its effectiveness. It is best to take the medication on an empty stomach or with a light meal.
• Avoid consuming large amounts of caffeine as it may interact with Tiropramide and increase the risk of side effects like jitteriness and anxiety.
• Avoid eating foods rich in tyramine (aged cheeses, cured meats, fermented foods) as Tiropramide may interact with tyramine, leading to elevated blood pressure.
• Consuming a high-fiber diet may reduce the absorption of Tiropramide, so consider taking the medication at least 1-2 hours before or after meals containing high fiber.
• Certain herbal supplements like St. John's Wort may affect the metabolism of Tiropramide and should be used with caution.
• Always follow the advice of your healthcare provider regarding specific food interactions and adjustments to your diet while taking Tiropramide.

Tiropramide Tablets should be stored in a cool and dry environment, preferably at room temperature, ensuring protection from direct sunlight and moisture. Keep the tablets in their original container, tightly sealed, to maintain their integrity and prevent exposure to external elements. It is crucial not to store them in bathrooms or near heat-emitting appliances to preserve their effectiveness. Regularly check the expiration date, and if the medication is no longer needed or has expired, do not dispose of it via household waste or water drainage systems. Consult your pharmacist or healthcare professional for guidance on proper disposal methods to ensure environmental safety. Keep the medication securely stored, away from children, to prevent accidental consumption.

Following are the quick tips for Tiropramide Tablet:

• Ensure you take the tablet as directed by your doctor for best results.
• Maintain a consistent daily dose timing to maximize effectiveness.
• Swallow the tablet whole with water; do not crush or chew.
• Avoid consuming alcohol while taking this medication.
• If you experience dizziness, refrain from driving or operating heavy machinery.
• Store the tablets in a cool, dry place, away from direct sunlight.
• Inform your doctor about any other medications you are taking to prevent potential interactions.
• Do not share your medication with others, even if their symptoms are similar.