Marifen (100mg) 30 Tablets

Mefenamic acid, a non-steroidal anti-inflammatory drug (NSAID), exerts its mechanism of action primarily through the inhibition of cyclooxygenase (COX) enzymes, specifically COX-1 and COX-2. By blocking these enzymes, mefenamic acid interferes with the production of prostaglandins, which are key mediators of inflammation and pain. This inhibition occurs at the site of inflammation, where mefenamic acid acts to reduce the formation of prostaglandin precursors from arachidonic acid. As a result, it effectively diminishes pain, inflammation, and fever by lowering the production of prostaglandins, which are responsible for amplifying the inflammatory response and sensitizing pain receptors. The drug's targeted action on COX enzymes contributes to its analgesic, antipyretic, and anti-inflammatory properties, making it effective in managing various conditions where pain and inflammation are prevalent.

Nonsteroidal anti-inflammatory drug (NSAID)

Tablet

The following are the uses of Mefenamic Acid 100mg Tablet:

• Used for relieving menstrual pain and discomfort.
• Used to reduce inflammation and ease pain associated with mild to moderate muscle aches and injuries.
• Used for treating headaches and migraines, providing pain relief.
• Used to manage pain and inflammation caused by certain joint conditions.
• Used to reduce fever and alleviate pain in conditions like flu or toothaches.
• Used for managing post-operative pain and inflammation.
• Used for its anti-inflammatory properties to treat conditions like rheumatoid arthritis.

In the case of an overdose of Mefenamic Acid 100mg Tablets, symptoms may include nausea, vomiting, diarrhea, and abdominal pain. More severe cases can lead to dizziness, confusion, and even loss of consciousness. It is crucial to seek medical advice promptly if an overdose is suspected. Treatment for overdose may involve supportive care, gastric decontamination, and monitoring of vital signs and kidney function. Early intervention can help manage potential complications effectively.

In the case of a missed dose of Mefenamic Acid 100mg Tablet, it is recommended to take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed one and continue with your regular dosing schedule. Do not double the dose to make up for a missed one, as this may increase the risk of side effects. If you miss multiple doses, contact your healthcare provider for guidance on how to safely resume your medication. It is important to maintain a consistent dosing schedule for the medication's effectiveness.

To take Mefenamic Acid 100mg Tablet, swallow the tablet whole with a full glass of water, preferably with or after food, as directed by your healthcare professional, and follow the prescribed dosage and duration according to your medical condition.

Following are the conditions or situations when Mefenamic Acid 100mg Tablet should not be taken:

• Allergy Do not take if you have a known allergy or hypersensitivity to Mefenamic Acid or any other NSAIDs (Non-Steroidal Anti-Inflammatory Drugs).
• Active Peptic Ulcer Contraindicated in patients with active or recent peptic ulcer, as it can worsen the condition.
• Severe Heart Failure Should not be used in individuals with severe heart failure or cardiovascular disease.
• Severe Renal Impairment Not recommended for patients with severe kidney disease or significantly impaired renal function.
• Aspirin Allergy Avoid if you have a history of allergic reactions to Aspirin or other salicylates.
• Third Trimester of Pregnancy Mefenamic Acid should not be used during the third trimester due to potential harm to the fetus and possible complications.
• Severe Dehydration Not suitable for individuals who are severely dehydrated, as it may affect kidney function.

The side effects of Mefenamic Acid 100mg Tablet may include:

• Nausea and vomiting
• Diarrhea
• Stomach pain or cramps
• Headache
• Dizziness or lightheadedness
• Skin rash or itching
• Ringing in the ears (tinnitus)
• Increased blood pressure

Following are the precautions and warnings for Mefenamic Acid 100mg Tablet:

• Do not use in patients with a known hypersensitivity or allergy to Mefenamic Acid or other non-steroidal anti-inflammatory drugs (NSAIDs).
• Exercise caution in patients with a history of gastrointestinal bleeding, ulcers, or other gastrointestinal disorders, as this medication may increase the risk of gastrointestinal complications.
• Patients with kidney or liver disease should be closely monitored as Mefenamic Acid may affect these organs.
• Avoid using this medication in patients with severe heart failure or high blood pressure unless advised by a doctor.
• Mefenamic Acid may cause dizziness or drowsiness; patients should avoid driving or operating heavy machinery until they know how the medication affects them.
• Not recommended for use during pregnancy, especially in the third trimester. Consult a healthcare professional for advice.
• Breastfeeding women should seek medical advice before taking this medication as it may pass into breast milk.

Following are the drug interactions for Mefenamic Acid 100mg Tablet:

• May decrease the effectiveness of oral contraceptives, requiring additional contraceptive measures.
• Increased risk of gastrointestinal bleeding when combined with other non-steroidal anti-inflammatory drugs (NSAIDs) or corticosteroids.
• Can reduce the renal excretion of lithium and methotrexate, increasing their levels and potential toxicity.
• Potentially elevated blood pressure when used with angiotensin-converting enzyme (ACE) inhibitors or angiotensin II receptor blockers (ARBs).
• Mefenamic acid may interfere with the antiplatelet effect of low-dose aspirin, reducing its cardioprotective benefits.
• Increased risk of bleeding with anticoagulants like warfarin, requiring close monitoring of coagulation parameters.
• Potential reduction in the efficacy of diuretics, especially loop diuretics, due to inhibition of prostaglandin synthesis.

Following are the food interactions for Mefenamic Acid 100mg Tablet:

• Avoid excessive caffeine intake from coffee, tea, or energy drinks as it may increase the risk of side effects like nervousness, insomnia, and rapid heartbeat.
• Grapefruit and grapefruit juice should be limited as they can affect the metabolism of Mefenamic Acid, potentially leading to increased drug levels and side effects.
• Alcohol consumption should be minimized as it may increase the risk of gastrointestinal bleeding and liver toxicity.
• Avoid high-sodium foods, as Mefenamic Acid can cause sodium retention, leading to fluid retention and increased blood pressure.
• Dairy products like milk, cheese, and yogurt may decrease the absorption of Mefenamic Acid, so consider taking the medication with a non-dairy meal.
• Avoid foods rich in vitamin K, such as spinach, kale, and broccoli, as Mefenamic Acid can interfere with blood clotting, and vitamin K can counteract this effect.
• Limit spicy foods as they can irritate the stomach and potentially worsen gastrointestinal side effects associated with Mefenamic Acid.
• Maintain a balanced diet and ensure adequate hydration to minimize potential drug interactions and side effects.

Mefenamic Acid 100mg Tablets should be stored in a secure and dry location, preferably in a medicine cabinet, at room temperature, ensuring it remains protected from light, heat, and moisture. It is crucial to keep the tablets in their original packaging, tightly sealed, to maintain their integrity and prevent contamination. When disposing of unused or expired tablets, it is important to avoid flushing them down the toilet or sink. Instead, consult your pharmacist or local waste management guidelines for environmentally safe disposal methods. Always keep medications out of children's reach to prevent accidental consumption, and ensure that the storage area is inaccessible to them. Proper storage and disposal practices are essential to maintain the effectiveness of the medication and safeguard the well-being of your household.

Following are the quick tips for Mefenamic Acid 100mg Tablet:

• Consult your doctor for the correct dosage and duration of treatment tailored to your condition.
• Swallow the tablet whole with water; do not crush, chew, or break it.
• Take it with or after food to prevent stomach irritation.
• Maintain a consistent schedule by taking the tablet at the same time each day.
• Do not lie down immediately after taking the tablet; stay upright to prevent irritation.
• Inform your doctor about all medications you're taking to avoid potential interactions.
• If you experience severe stomach pain, black stools, or vomiting, seek medical attention promptly.