Maxum (2g) 10ml, 1 Ampoule Injection

Maxum (2g) 10ml, 1 Ampoule Injection

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  • Manufacturer Highnoon Laboratories Ltd.
  • Generic Name

    Cefepime 2000mg

Healthwire Pharmacy Ratings & Reviews (1500+)

4.9/ 5
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Product Information

  • Description
  • Ingredients
  • Drug Class
  • Dosage Form
  • Uses
  • In case of Overdose
  • Missed Dose
  • How To Use
  • When Not to Use
  • Side Effects
  • Precautions & Warnings
  • Drug Interactions
  • Food Interactions
  • Storage/Disposal
  • Quick Tips, if any
  • Description

    Cefepime, a 2000mg injection, exerts its bactericidal effect by interfering with the synthesis of the bacterial cell wall. It selectively binds to specific penicillin-binding proteins, which are vital for maintaining the structural integrity of the bacterial cell wall. This binding inhibits the cross-linking of peptidoglycan strands, disrupting the cell wall formation and ultimately leading to cell lysis and bacterial death. Cefepime's broad-spectrum activity encompasses a wide range of Gram-positive and Gram-negative bacteria, making it effective against various pathogens.

  • Ingredients

    Cefepime 2000mg

  • Drug Class

    fourth-generation cephalosporin.

  • Dosage Form

    injection

  • Uses

    The following are the uses of Cefepime 2000mg injection:

    • Used for treating severe bacterial infections that require high-dose antibiotic therapy, such as hospital-acquired pneumonia.
    • Used for combating infections caused by multiple drug-resistant bacteria, ensuring effective treatment even when other antibiotics fail.
    • Used for treating complicated skin and skin structure infections, helping to control and eliminate the infection.
    • Used in intra-abdominal infections to prevent and manage potential complications.
    • Used for managing febrile neutropenia, a condition where individuals with low white blood cells experience fever.
    • Used for surgical prophylaxis to prevent infections during and after specific surgical procedures.
    • Used for treating urinary tract infections, particularly those caused by resistant bacteria.
  • In case of Overdose

    In the case of an overdose of Cefepime 2.0g injection, it is important to be aware of potential adverse effects. Symptoms may include severe nausea, vomiting, and seizures. In severe cases, an overdose can lead to neurological issues, such as confusion, dizziness, and decreased consciousness. Immediate medical intervention is necessary, and healthcare professionals should be contacted to provide appropriate treatment and supportive care to manage the overdose effectively.

  • Missed Dose

    In the case of a missed dose of Cefepime 2000mg injection, it is important to administer the medication as soon as possible. If it is almost time for the next scheduled dose, skip the missed dose and continue with the regular dosing schedule. Do not double the dose to make up for a missed one. However, if multiple doses have been missed, it is recommended to contact your healthcare professional for advice on how to safely resume the medication, especially if the missed doses are within a critical treatment window. They will provide guidance based on your specific situation.

  • How To Use

    To administer Cefepime 2.0 g injection, reconstitute the powder with the provided sterile water, gently swirl to dissolve, and inject the entire contents intramuscularly or intravenously as directed by your healthcare provider, ensuring proper aseptic technique.

  • When Not to Use

    Here are the conditions and situations when Cefepime 2.0 g injection should not be used:

    • Should not be administered to individuals with a known allergy to Cefepime or other cephalosporin antibiotics.
    • Contraindicated in patients with a history of severe hypersensitivity reactions to beta-lactam antibiotics.
    • Not suitable for patients with severe renal impairment without appropriate dose adjustment.
    • Should be avoided in patients with a history of seizures or conditions that increase the risk of seizures.
    • Not recommended for patients with a history of severe or life-threatening diarrhea caused by antibiotics.
    • Contraindicated in patients with a documented infection caused by organisms resistant to Cefepime.
    • Should not be used in patients with a history of Stevens-Johnson syndrome or toxic epidermal necrolysis.
  • Side Effects

    Side effects of Cefepime 2000mg Injection:

    • Allergic reactions (e.g., rash, itching, swelling)
    • Diarrhea
    • Nausea
    • Vomiting
    • Fever
    • Headache
    • Dizziness
    • Abdominal pain
    • Seizures (rare)
    • Changes in blood cell counts (e.g., low white blood cells, anemia)
    • Kidney problems (e.g., changes in urine output)
    • Injection site reactions (e.g., pain, redness, swelling)
    • Confusion or agitation (especially in older adults)
  • Precautions & Warnings

    Following are the precautions and warnings for Cefepime 2000mg Injection:

    • Avoid use in patients with known hypersensitivity to cefepime, other cephalosporins, or any other components of the injection.
    • Use with caution in patients with a history of penicillin allergy, as cross-reactivity may occur.
    • Not recommended for use in patients with severe renal impairment without dose adjustment, as the drug is primarily excreted through the kidneys.
    • Monitor renal function closely during treatment, especially in patients with pre-existing renal conditions.
    • May cause gastrointestinal disturbances such as diarrhea, nausea, or vomiting; monitor for signs of Clostridium difficile-associated diarrhea.
    • Use with caution in elderly patients, as they may be more susceptible to adverse reactions such as confusion or seizures.
    • Prolonged use may lead to superinfection or fungal overgrowth; monitor patients for signs of secondary infections.
    • Cefepime may cause false-positive results on certain urine glucose tests; confirm with alternative testing methods.
    • Overuse or misuse of antibiotics can lead to antibiotic resistance; ensure proper use according to healthcare provider’s guidance.
    • Pregnant or breastfeeding women should consult a healthcare provider before using this medication.
    • If allergic reactions (such as rash, swelling, or difficulty breathing) or any severe side effects occur, discontinue use and seek medical attention immediately.
  • Drug Interactions

    Following are the drug interactions for Cefepime 2000mg injection:

    • Probenecid can increase the risk of cefepime toxicity by decreasing its renal excretion.
    • Nephrotoxic drugs like aminoglycosides or diuretics may increase the risk of kidney damage when used with cefepime.
    • Concomitant use with other nephrotoxic agents such as colistin or vancomycin may further elevate the risk of kidney injury.
    • The effectiveness of oral contraceptives may be reduced due to cefepime's potential to decrease estrogen levels.
    • Cefepime may alter the efficacy of anticoagulants, requiring close monitoring of coagulation parameters.
    • Drugs that affect renal function, such as NSAIDs or ACE inhibitors, may influence cefepime elimination.
    • Caution is advised when using cefepime with myelotoxic agents, as it may increase the risk of hematologic adverse effects.
  • Food Interactions

    Following are the food interactions for Cefepime 2000mg injection:

    • Avoid alcohol consumption during the treatment, as it may increase the risk of side effects and affect the antibiotic's effectiveness.
    • Cefepime levels may be reduced by high-fat meals, potentially impacting its efficacy.
    • Grapefruit and grapefruit juice should be avoided as they can interfere with the liver enzymes, affecting Cefepime's metabolism.
    • Avoid consuming foods high in sodium as Cefepime contains sodium, and excessive sodium intake may lead to fluid retention and elevated blood pressure.
    • Maintain adequate hydration and ensure a balanced diet to support overall health during the treatment.
    • There are no specific food restrictions with Cefepime, but it's advisable to follow a healthy diet to aid recovery.
    • Always inform your healthcare provider about your dietary habits to ensure the medication's optimal effectiveness.
  • Storage/Disposal

    Cefepime 2000mg injection should be stored in a controlled environment, preferably in a cool and dry place, maintaining a temperature between 20°C and 25°C (68°F to 77°F). Protect the injection from direct sunlight, excessive heat, and freezing conditions, as these can degrade the medication. Store it in its original packaging, ensuring the container is tightly sealed to maintain sterility. Do not use the injection if the solution appears discolored or contains particles. Proper disposal is crucial; do not discard unused or expired medication in regular trash or flush it down the toilet. Contact your healthcare provider or pharmacist for guidance on safe disposal methods to minimize environmental impact. Keep the injection out of the reach of children and pets to prevent accidental exposure.

  • Quick Tips, if any

    Following are the quick tips for Cefepime 2000mg injection:

    • Cefepime is a powerful antibiotic, ensure its necessity before administration.
    • Administer the injection as directed by your healthcare professional.
    • Verify the dosage and patient's details to ensure accurate administration.
    • Inject the medication slowly to minimize discomfort.
    • Dispose of used needles and syringes safely to prevent injuries and infections.
    • If you experience any allergic reactions or severe side effects, seek immediate medical attention.
    • Store the medication as directed, away from direct sunlight and moisture.

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