Mectin (6mg) 10 Tablets

Ivermectin, an active ingredient in Ivermectin Tablets, acts primarily by binding to specific chloride ion channels in the cell membranes of parasites, particularly in the muscle and nerve cells of certain parasitic roundworms and arthropods. This binding causes an increase in the permeability of these channels to chloride ions, leading to hyperpolarization of the cell membrane. The hyperpolarization results in paralysis and eventual death of the targeted parasites. The drug selectively targets these channels in invertebrates, as the channels present in mammals are less sensitive to ivermectin, thus allowing for a wide margin of safety in therapeutic doses. This mechanism of action is particularly effective against parasitic infections caused by certain nematodes and arthropods, making Ivermectin a valuable antiparasitic agent.

Ivermectin

Antiparasitic Drug

Tablet

The following are the uses of Ivermectin Tablet:

• Used for treating parasitic infections, particularly those caused by roundworms, hookworms, and whipworms.
• Used for controlling and preventing river blindness (Onchocerciasis) in affected areas.
• Used for treating strongyloidiasis, a parasitic infection caused by a type of roundworm.
• Used for addressing scabies infestations, effectively eliminating mites.
• Used for managing certain cases of head lice infestations.
• Used for treating rosacea, a skin condition, by reducing inflammation and improving skin appearance.
• Used for controlling and treating filariasis, a parasitic worm infection.

In the case of an overdose of Ivermectin Tablets, it is important to recognize the signs and symptoms, which may include dizziness, nausea, vomiting, and in severe cases, central nervous system effects such as seizures or coma. Prompt medical attention is advised, and treatment will focus on managing the symptoms and providing supportive care. The severity of the overdose can vary depending on the amount ingested, and individuals should not hesitate to seek medical assistance to ensure appropriate treatment and monitoring.

In the case of a missed dose of Ivermectin Tablet, it is important to take the medication as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you miss multiple doses, contact your healthcare provider for guidance, as they may recommend adjusting your dosage or provide specific instructions to ensure you receive the correct amount of medication.

To take Ivermectin Tablet, swallow the tablet whole with a full glass of water on an empty stomach, preferably after fasting for at least 2 hours, as directed by your healthcare provider or the instructions on the prescription label.

Following are the circumstances in which Ivermectin Tablet should not be taken:

• Do not take if you are allergic to any of the components in the tablet, particularly Ivermectin.
• Avoid using if you have a known history of liver problems or reduced liver function.
• Not suitable for individuals with certain parasitic infections, such as Loa loa (African eye worm) or onchocerciasis (river blindness), unless under strict medical supervision.
• Should not be used in patients with known hypersensitivity to other drugs with a similar mechanism of action.
• Contraindicated in patients with severe uncontrolled infections, as the drug's action may lead to an increased risk of severe side effects.
• Not recommended for individuals with a compromised immune system, such as those with HIV/AIDS, without proper medical evaluation.
• Avoid using Ivermectin if you have a history of seizures or neurological disorders.
• Do not administer to children weighing less than 15 kg or those who are under 5 years old, except under the advice and supervision of a healthcare professional.
• Should not be used in combination with certain medications, such as warfarin, without adjusting the dosage and monitoring for potential interactions.
• Not suitable for individuals with a known history of severe lung or respiratory disorders.

The side effects of Ivermectin Tablet may include:

• Nausea and vomiting
• Diarrhea
• Stomach pain or cramping
• Dizziness
• Itching or skin rash
• Fatigue and weakness
• Facial or limb swelling
• Rapid heart rate

Following are the precautions and warnings for Ivermectin Tablet:

• Do not use in patients with known hypersensitivity to Ivermectin or other ingredients in the formulation.
• Ivermectin is not recommended for use in patients with severe liver disease, as it is primarily metabolized in the liver.
• Caution should be exercised in patients with a history of seizures, as Ivermectin can lower the seizure threshold.
• Elderly patients may be more sensitive to the effects of Ivermectin, so dosage adjustments might be necessary.
• This medication should be used with caution in individuals with a compromised immune system, as they may be more susceptible to infections.
• Ivermectin can cause dizziness; patients should be advised to avoid driving or operating heavy machinery until they know how the medication affects them.
• Patients with certain parasite infections, especially those with high worm loads, may experience serious side effects. Close monitoring is required in such cases.

Following are the drug interactions for Ivermectin Tablet:

• Co-administration with warfarin may increase the risk of bleeding due to potentiated anticoagulant effects.
• Macrolide antibiotics like azithromycin can inhibit the metabolism of ivermectin, leading to increased plasma concentrations.
• Concomitant use with efavirenz or nevirapine may reduce ivermectin exposure, potentially decreasing its efficacy.
• Ivermectin can potentiate the effects of other drugs that cause central nervous system depression, such as benzodiazepines and barbiturates.
• Certain anti-fungal drugs like ketoconazole and itraconazole can increase ivermectin levels in the body.
• Taking ivermectin with tubocurarine or other neuromuscular blockers can prolong the neuromuscular blockade and respiratory depression.
• Rifampicin can decrease the effectiveness of ivermectin by inducing its metabolism.

Following are the food interactions for Ivermectin Tablet:

• Grapefruit juice should be avoided as it can increase the concentration of Ivermectin in the blood, leading to potential side effects.
• Fatty meals may affect the absorption of Ivermectin, so it is recommended to take the tablet on an empty stomach.
• Alcohol consumption should be limited as it can increase the risk of certain side effects, especially when used for treating parasitic infections.
• Dairy products like milk, cheese, and yogurt can potentially decrease the absorption of Ivermectin, so it is advised to separate them by a few hours.
• Vitamin C-rich foods or supplements might reduce the effectiveness of Ivermectin, so it's best to avoid taking them together.
• Green leafy vegetables, when consumed in large amounts, may interfere with Ivermectin's action due to their potential to bind with the drug.
• Avoid caffeine-rich foods and beverages as they might enhance the side effects of Ivermectin, especially nervous system-related symptoms.
• Always follow the advice of your healthcare provider regarding any specific dietary restrictions or recommendations while using Ivermectin.

Ivermectin Tablets should be stored in a cool, dry area at room temperature, ideally between 68°F and 77°F (20°C and 25°C). Protect the tablets from excessive heat, moisture, and direct sunlight, as these conditions can degrade the medication. Keep the tablets in their original container, tightly sealed, to maintain their integrity and prevent exposure to air and humidity. It is crucial to dispose of any unused or expired Ivermectin Tablets properly; do not flush them down the toilet or discard them into drainage systems. Consult your pharmacist or healthcare provider for guidance on safe disposal practices in your area. Ensure that the medication is kept out of the reach of children and pets to prevent accidental consumption, which can be harmful.

Following are the quick tips for Ivermectin Tablet:

• Consult your doctor before taking this medication, especially if you have liver or kidney problems.
• Take the tablet on an empty stomach, at least 1 hour before or 2 hours after a meal.
• Ensure you understand the dosage instructions and take the correct amount as prescribed.
• Do not crush, chew, or break the tablet; swallow it whole with a full glass of water.
• Avoid alcohol consumption while taking this medication as it may increase side effects.
• Store the tablets in a cool, dry place, away from direct sunlight and moisture.
• Inform your doctor about all medications you are currently taking to avoid potential interactions.